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The map label for this gene is gatC [H]

Identifier: 218550762

GI number: 218550762

Start: 3536031

End: 3537419

Strand: Direct

Name: gatC [H]

Synonym: EFER_3473

Alternate gene names: 218550762

Gene position: 3536031-3537419 (Clockwise)

Preceding gene: 218550761

Following gene: 218550763

Centisome position: 77.06

GC content: 50.76

Gene sequence:

>1389_bases
GTGCGCTCTCGCCTGAAAAAGAGGTTTATTATGAACGATATCGCGCATACCCTCTATAATATTGTGCAATATATATTGGG
ATTTGGCCCGACGGTAATGTTGCCGTTGGTGTTATTTATTCTTGCTCTCTGTTTTAAAGTAAAACCCGCTAAAGCCTTAC
GTTCGTCATTAACAGTCGGCATTGGTTTTGTCGGTATTTATGCCATTTTCGATATTCTTACCAGCAATGTCGGGCCTGCG
GCCCAGGCGATGGTTGAACGCACCGGAATTAATTTACCGGTGGTGGATTTAGGCTGGCCGCCGCTTTCCGCTATTACATG
GGGTTCCCCAATTGCCCCATTTGTTATTCCCCTGACCATTCTGATTAACGTGGCGATGCTGGCGTTAAATAAAACCCGCA
CCGTTGACGTAGATATGTGGAACTACTGGCATTTTGCCCTTGCTGGTACGCTGGTTTATTACAGCACCGGCAGCCTGTTC
TTTGGTTTGCTGGCGGCGGCGATTGCCGCAGTGGTGGTGCTAAAACTCGCCGACTGGTCTGCGCCACTGGTACAAAAATA
CTTTGGCCTGGAAGGGATCTCATTGCCGACGCTCTCTTCGGTGGTGTTCTTCCCGGTCGGTCTGCTGGTCGACAAAATCA
TCGACCATATCCCTGGCCTCAATCGTATTCATATCGACCCGGAAACCGTACAGAAAAAGTTTGGCATCTTCGGCGAACCG
ATGATGGTTGGCACTATTCTGGGCATTCTGCTCGGCGTAATTGCCGGATACGATTTCAAAAAAGTCTTGCTGCTTGGCAT
CAGCATTGGCGGTGTGATGTTCATCCTGCCACGCATGGTACGCATTCTGATGGAAGGTTTATTACCGCTGTCTGAAGCCA
TTAAAAAGTATCTCAATGCCAAATACCCTGACCGTGACGATCTCTATATCGGCCTGGATATCGCCGTTGCCGTAGGTAAC
CCGGCGATTATCTCCACCGCCCTGCTGCTGACGCCAATCTCGGTCTTTATCGCGTTTGTCCTTCCGGGTAATGAAGTCCT
GCCGCTTGGCGACCTTGCCAACCTGGCGGTAATGGCGTCGATGATCGCTTTAGCCAGCCGTGGCAATATTTTCCGCACCG
TTCTGGCGGCGATTCCGGTGATTATTGCCGACCTGTGGATTGCTACCAAAATCGCGCCGTTTATTACCGGAATGGCGAAA
GACGTTAACTTCAAATTTGCCGAAGGCTCCAGCGGCCAGGTTTCCAGTTTCCTTGATGGCGGTAACCCGTTCCGCTTCTG
GCTGCTGGAAATCTTCAACGGCAATCTCATCGCCATTGGTCTGGTGCCGGTTATCGCCCTGGTACTGTATGGCATTTTCC
GAATGACGCGGAGCACGGTTTATGCCTGA

Upstream 100 bases:

>100_bases
GGTATTGGCGAAGAGAAAGTACTGGCGCAAATTGTTTCGATCCTTAAAAAGTAATTAATAATAATTAATTTCAACCCACT
CCATCAGGCGCTAACGCGAG

Downstream 100 bases:

>100_bases
TAACAGCGCAGCTATCGTTATCGATATTGGCACCACCAATTGCAAAGTCACCTGCTTTTCCTGCCTGGACGCAACGACGT
TGGGCGCGCATAAATTCGTG

Product: phosphotransferase system permease IIC

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MRSRLKKRFIMNDIAHTLYNIVQYILGFGPTVMLPLVLFILALCFKVKPAKALRSSLTVGIGFVGIYAIFDILTSNVGPA
AQAMVERTGINLPVVDLGWPPLSAITWGSPIAPFVIPLTILINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSLF
FGLLAAAIAAVVVLKLADWSAPLVQKYFGLEGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPETVQKKFGIFGEP
MMVGTILGILLGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPDRDDLYIGLDIAVAVGN
PAIISTALLLTPISVFIAFVLPGNEVLPLGDLANLAVMASMIALASRGNIFRTVLAAIPVIIADLWIATKIAPFITGMAK
DVNFKFAEGSSGQVSSFLDGGNPFRFWLLEIFNGNLIAIGLVPVIALVLYGIFRMTRSTVYA

Sequences:

>Translated_462_residues
MRSRLKKRFIMNDIAHTLYNIVQYILGFGPTVMLPLVLFILALCFKVKPAKALRSSLTVGIGFVGIYAIFDILTSNVGPA
AQAMVERTGINLPVVDLGWPPLSAITWGSPIAPFVIPLTILINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSLF
FGLLAAAIAAVVVLKLADWSAPLVQKYFGLEGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPETVQKKFGIFGEP
MMVGTILGILLGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPDRDDLYIGLDIAVAVGN
PAIISTALLLTPISVFIAFVLPGNEVLPLGDLANLAVMASMIALASRGNIFRTVLAAIPVIIADLWIATKIAPFITGMAK
DVNFKFAEGSSGQVSSFLDGGNPFRFWLLEIFNGNLIAIGLVPVIALVLYGIFRMTRSTVYA
>Mature_462_residues
MRSRLKKRFIMNDIAHTLYNIVQYILGFGPTVMLPLVLFILALCFKVKPAKALRSSLTVGIGFVGIYAIFDILTSNVGPA
AQAMVERTGINLPVVDLGWPPLSAITWGSPIAPFVIPLTILINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSLF
FGLLAAAIAAVVVLKLADWSAPLVQKYFGLEGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPETVQKKFGIFGEP
MMVGTILGILLGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPDRDDLYIGLDIAVAVGN
PAIISTALLLTPISVFIAFVLPGNEVLPLGDLANLAVMASMIALASRGNIFRTVLAAIPVIIADLWIATKIAPFITGMAK
DVNFKFAEGSSGQVSSFLDGGNPFRFWLLEIFNGNLIAIGLVPVIALVLYGIFRMTRSTVYA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=438, Percent_Identity=40.6392694063927, Blast_Score=342, Evalue=3e-95,
Organism=Escherichia coli, GI1790758, Length=411, Percent_Identity=39.9026763990268, Blast_Score=298, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 50040; Mature: 50040

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRLKKRFIMNDIAHTLYNIVQYILGFGPTVMLPLVLFILALCFKVKPAKALRSSLTVG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGFVGIYAIFDILTSNVGPAAQAMVERTGINLPVVDLGWPPLSAITWGSPIAPFVIPLTI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHH
LINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSLFFGLLAAAIAAVVVLKLADWS
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
APLVQKYFGLEGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPETVQKKFGIFGEP
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCCCH
MMVGTILGILLGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
KYPDRDDLYIGLDIAVAVGNPAIISTALLLTPISVFIAFVLPGNEVLPLGDLANLAVMAS
CCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHH
MIALASRGNIFRTVLAAIPVIIADLWIATKIAPFITGMAKDVNFKFAEGSSGQVSSFLDG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHCC
GNPFRFWLLEIFNGNLIAIGLVPVIALVLYGIFRMTRSTVYA
CCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSRLKKRFIMNDIAHTLYNIVQYILGFGPTVMLPLVLFILALCFKVKPAKALRSSLTVG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGFVGIYAIFDILTSNVGPAAQAMVERTGINLPVVDLGWPPLSAITWGSPIAPFVIPLTI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHH
LINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSLFFGLLAAAIAAVVVLKLADWS
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
APLVQKYFGLEGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPETVQKKFGIFGEP
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCCCH
MMVGTILGILLGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
KYPDRDDLYIGLDIAVAVGNPAIISTALLLTPISVFIAFVLPGNEVLPLGDLANLAVMAS
CCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHH
MIALASRGNIFRTVLAAIPVIIADLWIATKIAPFITGMAKDVNFKFAEGSSGQVSSFLDG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHCC
GNPFRFWLLEIFNGNLIAIGLVPVIALVLYGIFRMTRSTVYA
CCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]