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The map label for this gene is feoB [H]

Identifier: 218550667

GI number: 218550667

Start: 3435498

End: 3437819

Strand: Direct

Name: feoB [H]

Synonym: EFER_3377

Alternate gene names: 218550667

Gene position: 3435498-3437819 (Clockwise)

Preceding gene: 218550666

Following gene: 218550668

Centisome position: 74.87

GC content: 54.05

Gene sequence:

>2322_bases
ATGAAAAAATTAACCATTGGCTTAATTGGTAATCCAAATTCTGGCAAGACAACGTTATTTAACCAGCTCACTGGTGCACG
TCAGCGTGTAGGTAACTGGGCTGGCGTTACCGTCGAACGTAAAGAAGGGCAATTCTCCACCACCGATCATCAGGTCACGC
TGGTGGACCTGCCCGGCACCTATTCTCTGACCACCATCTCATCGCAGACCTCGCTCGATGAGCAAATCGCCTGCCACTAT
ATTTTGAGTGGTGACGCCGATCTGCTGATTAACGTGGTGGATGCGTCTAACCTTGAGCGTAACCTGTACCTGACACTGCA
ACTGCTGGAACTCGGCATTCCCTGCATCGTGGCGCTGAATATGCTCGACATTGCCGAGAAGCAAAATATTCGCATTGAAA
TTGATGCGCTGTCGGCACGTCTTGGCTGCCCGGTGATCCCGCTGGTATCAACCCGTGGTCGGGGTATTGAAGCGCTCAAG
CTGGCGATTGACCGCTATAAAGCTAACGACAATGTGGAACTGGTGCATTACGCACAGCCGCTGCTCAACGAAGCAGATTC
ACTGGCAAAAGTGATGCCTTCCGACATCCCGCTGAAACAACGTCGCTGGCTGGGCCTGCAAATGCTGGAAGGCGATATCT
ACAGCCGCGCTTACGCCGGTGAAGCGTCGCAGCATCTTGATGCCGCCCTTACCCGTCTGCGTAATGAGATGGACGATCCG
GCGCTACACATTGCCGATGCGCGTTACCAGTGTATTGCCGCCATTTGCGATGTGGTAAGCAACACCCTGACGGCAGAACC
CAGCCGTTTCACCACTGCGGTAGATAAAATCGTGCTCAACCGTTTCCTCGGTCTGCCGATTTTCCTCTTTGTGATGTACC
TGATGTTCCTGCTCGCTATCAACATCGGCGGGGCGTTACAACCGTTGTTTGACGTTGGTTCCGTAGCACTCTTTGTGCAT
GGTATTCAGTGGATTGGCTACACGCTCCACTTCCCGGACTGGCTGACTATCTTCCTTGCCCAGGGCCTGGGTGGCGGCAT
TAACACCGTTCTGCCACTGGTGCCGCAGATCGGTATGATGTACCTGTTCCTCTCCTTCCTTGAGGACTCCGGGTATATGG
CGCGTGCGGCGTTTGTGATGGACCGCCTGATGCAGGCGCTGGGCTTGCCGGGGAAATCCTTTGTACCGCTGATTGTCGGT
TTCGGTTGTAACGTACCGTCGGTAATGGGCGCACGTACGCTTGATGCACCGCGTGAGCGTCTGATGACCATTATGATGGC
ACCGTTTATGTCCTGCGGCGCGCGTCTGGCTATCTTCGCAGTATTTGCGGCTGCCTTCTTCGGGCAGAATGGCGCACTGG
CGGTCTTCTCGCTGTATGTCATCGGTATTGTGATGGCGGTGCTGACTGGCCTGATGCTCAAGTACACCATCATGCGCGGT
GAAGCGACGCCGTTTGTCATGGAGCTGCCGGTCTACCATGTACCACACGTTAAAAGCCTGATTATCCAGACCTGGCAGCG
TCTGAAAGGCTTCGTTCTGCGTGCGGGTAAAGTGATTATCATCGTCAGCATTTTCCTGAGCGCATTCAACAGCTTCTCGC
TGAGCGGGAAAATCGTCGATAACATCAACGACTCGGCACTGGCTTCCGTCAGCCGGGTGATCACCCCGGTCTTCAAGCCG
ATTGGCGTACATGAAGATAACTGGCAGGCAACTGTTGGCCTGTTTACAGGCGCAATGGCGAAAGAAGTGGTGGTGGGTAC
GCTCAACACCCTCTACACCGCAGAAAATATTCAGGACGAAGAGTTCAATCCGGCGGAATTTAACCTCGGTGAAGAGCTAT
TCAGCGCGGTAGATGAAACCTGGCAGAGCCTGAAAGACACCTTCAGTCTTAGCGTACTGATGAACCCCATTGAAGCGAGC
AAAGGCGACGGTGAAATGGGTACCGGAGCGATGGGCGTGATGGATCAGAAATTTGGAAGCGCAGCAGCTGCTTACAGCTA
CCTGATTTTCGTTCTGCTGTATGTACCGTGTATCTCGGTGATGGGCGCTATCGCGCGTGAATCCAGCCGTGGCTGGATGG
GCTTCTCCATCCTGTGGGGGCTAAATATCGCTTACTCGTTGGCAACATTGTTCTACCAGGTCGCCAGCTACAGCCAGCAT
CCAACCTACAGCCTGGTATGCATTCTGGCGGTTATCCTGTTTAACATCGTGGTTATCGGTTTGCTGCGTCGCGCGCGTAG
CCGGGTCGATATCGAACTGCTGGCAACACGCAAATCGGTAAGCAGTTGCTGTGCAGCCAGCACCACTGGCGATTGCCACT
AA

Upstream 100 bases:

>100_bases
ATTCATATCGAAACCCGTCGTGTAAGCCTGGTATTACGCAAAAAAGATCTGGCCTTATTAGAAGTTGAAGCGGTTTCCTG
TTAATACAGTGAGAACAACA

Downstream 100 bases:

>100_bases
TGGCTTCACTTATTCAGGTGCGTGATTTGCTGGCGTTACGGGGCCGTATGGAAGCGGCCCAGATAAGCCAGACACTGAAC
ACCCCGCAACCCATGATTAA

Product: ferrous iron transport protein B

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHY
ILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
LAIDRYKANDNVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALTRLRNEMDDP
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVH
GIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVG
FGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYVIGIVMAVLTGLMLKYTIMRG
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKP
IGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEAS
KGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH

Sequences:

>Translated_773_residues
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHY
ILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
LAIDRYKANDNVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALTRLRNEMDDP
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVH
GIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVG
FGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYVIGIVMAVLTGLMLKYTIMRG
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKP
IGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEAS
KGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH
>Mature_773_residues
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHY
ILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
LAIDRYKANDNVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALTRLRNEMDDP
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVH
GIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVG
FGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYVIGIVMAVLTGLMLKYTIMRG
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKP
IGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEAS
KGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH

Specific function: GTP-driven Fe(2+) uptake system [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the feoB (TC 9.A.8) family [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=773, Percent_Identity=99.2238033635188, Blast_Score=1577, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003373
- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate [H]

EC number: NA

Molecular weight: Translated: 84429; Mature: 84429

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGT
CCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEECCCC
YSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALN
EEEEEECCCCCCCHHHHEEEEECCCCEEEEEEECCCCCCCCCEEEEEHHHHCCHHHHHHH
MLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALKLAIDRYKANDNVELVHYAQP
HHHHHCCCCCEEEEEEEHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEHHHH
LLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALTRLRNEMDDP
HHHHHHHHHHHCCCCCCCHHHHHCCHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAI
CEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMM
CCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
YLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSVMGARTLDAPRER
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCHHHCCCCCCHHHHH
LMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYVIGIVMAVLTGLMLKYTIMRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVD
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEC
NINDSALASVSRVITPVFKPIGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHCH
AAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCC
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGT
CCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEECCCC
YSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALN
EEEEEECCCCCCCHHHHEEEEECCCCEEEEEEECCCCCCCCCEEEEEHHHHCCHHHHHHH
MLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALKLAIDRYKANDNVELVHYAQP
HHHHHCCCCCEEEEEEEHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEHHHH
LLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALTRLRNEMDDP
HHHHHHHHHHHCCCCCCCHHHHHCCHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAI
CEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMM
CCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
YLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSVMGARTLDAPRER
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCHHHCCCCCCHHHHH
LMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYVIGIVMAVLTGLMLKYTIMRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVD
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEC
NINDSALASVSRVITPVFKPIGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHCH
AAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCC
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]