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The map label for this gene is hopD [H]

Identifier: 218550597

GI number: 218550597

Start: 3369741

End: 3370214

Strand: Direct

Name: hopD [H]

Synonym: EFER_3306

Alternate gene names: 218550597

Gene position: 3369741-3370214 (Clockwise)

Preceding gene: 218550566

Following gene: 218550609

Centisome position: 73.44

GC content: 46.84

Gene sequence:

>474_bases
ATGGACGCTACCCTTCCCTTTCTGACTTTGTACGCTTGTTTAACAGCCCTACTTTTTTTCTGGGATGCAAAGCATGGCTT
GTTACCTGACAGATTTACGTGCCCATTACTCTGGTCAGGTCTTATGTTCTATCAAATTTGTCATCCTGACAATTTAGCCG
ATGCGTTATGGGGGGCGATTATTGGTTACGGCACATTCGCAGTCATTTACTGGGGATATCGCATACTGCGTCATAAAGAA
GGATTAGGTTATGGCGATGTGAAGTTTCTCGCGGCCCTTGGCGCCTGGCATACATGGGCATTCCTGCCACGGCTGGTTTT
CCTTGCTGCTTCATTCGCTTGCGGAGCCGTAGTTATTGGTCTGCTTATGAGAGGAAAAGAATCATTAAAAAACCCGCTGC
CTTTTGGACCATACCTGGCGACTGCGGGTTTCGTTGTAGGTTGGGACAGCCTGCTTTCTGAATTTAATCTTTAA

Upstream 100 bases:

>100_bases
AGCGTTTTTCACCGGAACCAGGTTAACAAAGCCGCGATTTCTCTGTTGCTGAGTATCAGGAATTATTCGATGGTGCTACT
CCAATTACAGAGGATGTTTT

Downstream 100 bases:

>100_bases
CTTTGATTTGTGATTGCAGGTAATTTTGCAGGCCAATTTTGCCAATGAGATCTAACTCTGTTTCGAGCCAGTCGATATGC
CCTTCTTCATCAGCAAGGAT

Product: bifunctional prepilin peptidase HopD: leader peptidase; methyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MDATLPFLTLYACLTALLFFWDAKHGLLPDRFTCPLLWSGLMFYQICHPDNLADALWGAIIGYGTFAVIYWGYRILRHKE
GLGYGDVKFLAALGAWHTWAFLPRLVFLAASFACGAVVIGLLMRGKESLKNPLPFGPYLATAGFVVGWDSLLSEFNL

Sequences:

>Translated_157_residues
MDATLPFLTLYACLTALLFFWDAKHGLLPDRFTCPLLWSGLMFYQICHPDNLADALWGAIIGYGTFAVIYWGYRILRHKE
GLGYGDVKFLAALGAWHTWAFLPRLVFLAASFACGAVVIGLLMRGKESLKNPLPFGPYLATAGFVVGWDSLLSEFNL
>Mature_157_residues
MDATLPFLTLYACLTALLFFWDAKHGLLPDRFTCPLLWSGLMFYQICHPDNLADALWGAIIGYGTFAVIYWGYRILRHKE
GLGYGDVKFLAALGAWHTWAFLPRLVFLAASFACGAVVIGLLMRGKESLKNPLPFGPYLATAGFVVGWDSLLSEFNL

Specific function: Cleaves Type-4 Fimbrial Leader Sequence And Methylates The N-Terminal (Generally Phe) Residue (By Similarity). [C]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI1789732, Length=138, Percent_Identity=40.5797101449275, Blast_Score=81, Evalue=3e-17,
Organism=Escherichia coli, GI87082194, Length=124, Percent_Identity=37.9032258064516, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF01478 Peptidase_A24 [H]

EC number: 3.4.23.43

Molecular weight: Translated: 17471; Mature: 17471

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATLPFLTLYACLTALLFFWDAKHGLLPDRFTCPLLWSGLMFYQICHPDNLADALWGAI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWAFLPRLVFLAASFACGAVVIG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMRGKESLKNPLPFGPYLATAGFVVGWDSLLSEFNL
HHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDATLPFLTLYACLTALLFFWDAKHGLLPDRFTCPLLWSGLMFYQICHPDNLADALWGAI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWAFLPRLVFLAASFACGAVVIG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMRGKESLKNPLPFGPYLATAGFVVGWDSLLSEFNL
HHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA