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The map label for this gene is aapQ [H]

Identifier: 218550553

GI number: 218550553

Start: 3336215

End: 3337396

Strand: Direct

Name: aapQ [H]

Synonym: EFER_3248

Alternate gene names: 218550553

Gene position: 3336215-3337396 (Clockwise)

Preceding gene: 218550552

Following gene: 218550554

Centisome position: 72.7

GC content: 49.58

Gene sequence:

>1182_bases
ATGTCTCATCGCCGCCCGTCCGTTAAAGGCTCACTCTCCTTTGCCAACCCTACGGTTCGCGCCTGGTTATTCCAGATCCT
TGCCGTTGTTGCTGTTGTCGGCATTATTGGTTGGTTATTTCACAACACCGTAACGAATCTCAGTAATCGCGGCATTACTT
CAGGTTTTGCCTTCCTGGACCGCGGCGCTGGCTTCGGTATTATCCAGCATTTGATCGATTACCAGCAGGGTGATACCTAC
GGACGCGTTTTCATTGTTGGCTTACTCAATACGCTACTGGTTTCGGCATTGTGTATTGTGTTCGCTTCTGTTCTGGGCTT
TTTTATCGGTCTGGCGAGACTTTCGGATAACTGGCTGCTACGAAAGCTTTCCACAATTTATATTGAGATCTTCCGTAATA
TTCCGCCCCTGCTGCAAATCTTCTTCTGGTACTTTGCCGTATTGCGCAATTTGCCCGGACCACGCCAGGCAGTGAGTGCA
TTTGATCTGGCCTTTTTAAGCAATCGTGGGCTTTATATTCCGTCGCCGCAGCTGGGAGACGGGTTCCTTGCATTTATCCT
GGCTGTTGTTATGGCTATAGCCCTTTCTGTTGGGCTATATCGCTTTAATAAAAAACACCAGATAAAGACCGGACAACTGC
GCCGAACCTGGCCGTTCGCCGTTGGGTTAATCATTGGCTTGCCTTTACTGGCGCAATGGCTTTTTGGCGCAGCACTGCAC
TGGGATGTTCCAGCCCTACAAGGTTTTAATTTCCGCGGCGGAATGGTTTTAATTCCTGAACTGGCAGCCTTAACGATGGC
GCTTTCGGTTTATACCTCTGCATTTATCGCCGAGATTATCCGCGCCGGGATTCAGGCAGTGCCTTATGGTCAACATGAAG
CTGCCAGGTCACTGGGATTGCCCAACCCGGTTACGCTACGCCAGGTCATTATTCCTCAGGCACTGCGAGTGATTATTCCT
CCATTAACCAGCCAGTATCTCAACATCGTCAAAAACTCCTCTCTTGCCGCCGCTATTGGCTATCCGGATATGGTTTCGCT
GTTTGCTGGCACCGTACTAAACCAGACAGGGCAAGCCATCGAGACGATAGCTATGACCATGTCGGTCTATCTGATTATCA
GTCTGACTATCTCGCTGCTGATGAATATTTATAACCGCCGCATCGCGATCGTTGAACGCTAA

Upstream 100 bases:

>100_bases
GGCGGTATTCAGTACGCGCCGCCCGTGCGTTAAGTCGGTGTGAGGTAATGAGCGTCGCTACGGCGGCGCTCTCTTCAGCG
TTATGGTTTCCGAGGTTTCT

Downstream 100 bases:

>100_bases
GGAGTCATGATGACAAAAGTATTGCTATCTCATCCCCCGCGCCCGACGAGCCATAACTCAAGTCGCGCTATGGTGTGGGT
GCGAAAAAATCTGTTCTCCA

Product: amino-acid ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSHRRPSVKGSLSFANPTVRAWLFQILAVVAVVGIIGWLFHNTVTNLSNRGITSGFAFLDRGAGFGIIQHLIDYQQGDTY
GRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
FDLAFLSNRGLYIPSPQLGDGFLAFILAVVMAIALSVGLYRFNKKHQIKTGQLRRTWPFAVGLIIGLPLLAQWLFGAALH
WDVPALQGFNFRGGMVLIPELAALTMALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIP
PLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER

Sequences:

>Translated_393_residues
MSHRRPSVKGSLSFANPTVRAWLFQILAVVAVVGIIGWLFHNTVTNLSNRGITSGFAFLDRGAGFGIIQHLIDYQQGDTY
GRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
FDLAFLSNRGLYIPSPQLGDGFLAFILAVVMAIALSVGLYRFNKKHQIKTGQLRRTWPFAVGLIIGLPLLAQWLFGAALH
WDVPALQGFNFRGGMVLIPELAALTMALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIP
PLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER
>Mature_392_residues
SHRRPSVKGSLSFANPTVRAWLFQILAVVAVVGIIGWLFHNTVTNLSNRGITSGFAFLDRGAGFGIIQHLIDYQQGDTYG
RVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSAF
DLAFLSNRGLYIPSPQLGDGFLAFILAVVMAIALSVGLYRFNKKHQIKTGQLRRTWPFAVGLIIGLPLLAQWLFGAALHW
DVPALQGFNFRGGMVLIPELAALTMALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPP
LTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER

Specific function: Probably part of the binding-protein-dependent transport system ydhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=393, Percent_Identity=96.1832061068702, Blast_Score=735, Evalue=0.0,
Organism=Escherichia coli, GI1786874, Length=123, Percent_Identity=39.0243902439024, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788226, Length=191, Percent_Identity=33.5078534031414, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786873, Length=130, Percent_Identity=34.6153846153846, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082239, Length=120, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787030, Length=134, Percent_Identity=31.3432835820896, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788645, Length=205, Percent_Identity=26.3414634146341, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43258; Mature: 43127

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
>Mature Secondary Structure 
SHRRPSVKGSLSFANPTVRAWLFQILAVVAVVGIIGWLFHNTVTNLSNRGITSGFAFLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RGAGFGIIQHLIDYQQGDTYGRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSAFDLAFLSNRGLYIPSPQLGD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCCCCCC
GFLAFILAVVMAIALSVGLYRFNKKHQIKTGQLRRTWPFAVGLIIGLPLLAQWLFGAALH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WDVPALQGFNFRGGMVLIPELAALTMALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGL
CCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
PNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAI
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHH
ETIAMTMSVYLIISLTISLLMNIYNRRIAIVER
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]