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The map label for this gene is aaeA [H]

Identifier: 218550525

GI number: 218550525

Start: 3303637

End: 3304569

Strand: Reverse

Name: aaeA [H]

Synonym: EFER_3219

Alternate gene names: 218550525

Gene position: 3304569-3303637 (Counterclockwise)

Preceding gene: 218550526

Following gene: 218550524

Centisome position: 72.02

GC content: 50.8

Gene sequence:

>933_bases
GTGAAAACACTAATAAGAAAACTCACGCGTACGGCGATTACGCTGGTACTGGTTATCCTGGCATTTATTGCCATTTTTCG
CGCCTGGGTCTACTACACGGAGTCACCGTGGACACGCGACGCCCGCTTTAGCGCCGATGTGGTGGCTATCGCCCCGGATG
TTGCCGGACTCATCACTAACGTCAATGTTCATGATAACCAGTTGGTGAAAAAAGGGCAGGTTCTGTTCACTATCGATCAG
CCACGTTATCAAAAAGCACTGGCAGAAGCGGAAGCTGATGTCGCGTATTACAGCGTGCTGGCACAGGAAAAGCGCCAGGA
AGCGAGTCGTCGTAATAGGCTGGGTGTACAGGCGATGTCTCGTGAAGAGATTGACCAGGCGAATAACGTCCTGCAAACGG
TGTTACACCAGTTAGCGAAAGCTCAGGCAACTCGTGACTTAGCTAAACTCGATCTTGAACGTACCGTGATCCGCGCGCCT
GCTGATGGCTGGGTAACTAACCTGAATGTATATACTGGTGAATTTATTACCCGAGGTTCAACGGCGGTTGCACTGGTAAA
ACAGAACACCTTCTATGTGCTGGCCTATATGGAAGAAACAAAGCTGGAAGGGGTTCGTCCTGGTTACCGGGCGGAAATTA
CACCACTGGGCAGTAACCGTGTGTTAAAAGGCACTGTTGATAGTATTGCTGCCGGGGTAACTAATGCCAGCAGTACCCGC
GATGCTAAAGGTATGGCGACCATTGATTCAAATCTGGAGTGGGTTCGCCTGGCACAACGTGTACCCGTACGGATACGCCT
TGACGCACAACCAGAAAATTTGTGGCCCGCAGGTACTACAGCAACGGTGGTGGTTACCGGGAAAGATGATCGTGACGAGA
GTCAGGATTCATTCTTTCGCAAAATGGCTCACCGACTGCGTGAGTTTGGTTAA

Upstream 100 bases:

>100_bases
ACTGGCATCTACGATTTTGTCTGGCATCCCGCGTTGTTTAACACTGCGCTCTATTGCTGTCTCTTCTACTTGATATCGCG
CCTGTTTGTTTGAGGTTTAA

Downstream 100 bases:

>100_bases
TCACGATGGGCATTTTTTCTATAGCTAACCAACATATTCGCTTTGCAGTCAAGCTGGCGAGCGCCATCGTGTTGACGCTG
TTTGTCGGTTTCCATTTTCA

Product: p-hydroxybenzoic acid efflux subunit AaeA

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKTLIRKLTRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITNVNVHDNQLVKKGQVLFTIDQ
PRYQKALAEAEADVAYYSVLAQEKRQEASRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
ADGWVTNLNVYTGEFITRGSTAVALVKQNTFYVLAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSIAAGVTNASSTR
DAKGMATIDSNLEWVRLAQRVPVRIRLDAQPENLWPAGTTATVVVTGKDDRDESQDSFFRKMAHRLREFG

Sequences:

>Translated_310_residues
MKTLIRKLTRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITNVNVHDNQLVKKGQVLFTIDQ
PRYQKALAEAEADVAYYSVLAQEKRQEASRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
ADGWVTNLNVYTGEFITRGSTAVALVKQNTFYVLAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSIAAGVTNASSTR
DAKGMATIDSNLEWVRLAQRVPVRIRLDAQPENLWPAGTTATVVVTGKDDRDESQDSFFRKMAHRLREFG
>Mature_310_residues
MKTLIRKLTRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITNVNVHDNQLVKKGQVLFTIDQ
PRYQKALAEAEADVAYYSVLAQEKRQEASRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
ADGWVTNLNVYTGEFITRGSTAVALVKQNTFYVLAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSIAAGVTNASSTR
DAKGMATIDSNLEWVRLAQRVPVRIRLDAQPENLWPAGTTATVVVTGKDDRDESQDSFFRKMAHRLREFG

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789637, Length=310, Percent_Identity=93.8709677419355, Blast_Score=599, Evalue=1e-173,
Organism=Escherichia coli, GI87081951, Length=273, Percent_Identity=39.9267399267399, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1790519, Length=301, Percent_Identity=30.8970099667774, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788711, Length=309, Percent_Identity=26.2135922330097, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790024, Length=254, Percent_Identity=25.1968503937008, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789041, Length=288, Percent_Identity=24.6527777777778, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 34624; Mature: 34624

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLIRKLTRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHEE
VNVHDNQLVKKGQVLFTIDQPRYQKALAEAEADVAYYSVLAQEKRQEASRRNRLGVQAMS
CCCCCHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
REEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEEECCC
TAVALVKQNTFYVLAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSIAAGVTNASSTR
EEEEEEECCCEEEEEEEECHHCCCCCCCCCEEEEECCCCCEEECCHHHHHHCCCCCCCCC
DAKGMATIDSNLEWVRLAQRVPVRIRLDAQPENLWPAGTTATVVVTGKDDRDESQDSFFR
CCCCEEEECCCHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHH
KMAHRLREFG
HHHHHHHHCC
>Mature Secondary Structure
MKTLIRKLTRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHEE
VNVHDNQLVKKGQVLFTIDQPRYQKALAEAEADVAYYSVLAQEKRQEASRRNRLGVQAMS
CCCCCHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
REEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEEECCC
TAVALVKQNTFYVLAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSIAAGVTNASSTR
EEEEEEECCCEEEEEEEECHHCCCCCCCCCEEEEECCCCCEEECCHHHHHHCCCCCCCCC
DAKGMATIDSNLEWVRLAQRVPVRIRLDAQPENLWPAGTTATVVVTGKDDRDESQDSFFR
CCCCEEEECCCHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHH
KMAHRLREFG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA