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The map label for this gene is nanR [H]

Identifier: 218550503

GI number: 218550503

Start: 3286065

End: 3286847

Strand: Reverse

Name: nanR [H]

Synonym: EFER_3197

Alternate gene names: 218550503

Gene position: 3286847-3286065 (Counterclockwise)

Preceding gene: 218550504

Following gene: 218550502

Centisome position: 71.63

GC content: 54.53

Gene sequence:

>783_bases
ATGAACGCATTTGATCCGCAAGCTGAAGATTCTACTACTACTATCGGTCGCAACTTGCGCAGCCGCCCGCTGGCGCGTAA
AAAACTCTCCGAAATGGTGGAAGAAGAGCTGGAGCAGATGATCCGCCGCCGCGAGTTTGGCGAAGGTGAGCAGTTGCCGT
CTGAGCGCGAACTGATGGCGTTCTTTAACGTCGGGCGACCTTCGGTGCGTGAAGCGCTGGCAGCATTAAAACGAAAAGGT
CTGGTGCAAATAAACAATGGAGAACGCGCCCGCGTCTCGCGTCCTTCGGCGGACACCATCATCGGCGAGCTTTCCGGCAT
GGCGAAAGATTTCCTTTCTCATCCTGGCGGGATTGCCCATTTCGAACAATTACGTCTGTTCTTTGAATCCAGCCTGGTGC
GCTATGCGGCTGAACATGCCACCGATGAGCAAATTGATTTGCTGGCAAAAGCACTGGAAATCAACAGTCAGTCGCTGGAT
AACAACGCGGCATTCATTCGTTCAGACGTTGATTTCCACCGCGTGTTGGCGGAGATCCCCGGCAACCCGATCTTTATGGC
GATCCATGTTGCCCTGCTCGATTGGCTGATCGCCGCGCGCCCAACCGTAGCTGATCAGGCTCTGCACGAGCATAACAACG
TTAGCTATCAACAGCATATTGCGATCGTTGACGCGATCCGCCGCCACGATCCCGATGAAGCCGATCGCGCGTTGCAATCG
CATCTCAACAGCGTTTCTGCCACCTGGCACGCCTTCGGCCAAACCACCCACAAAAAGAAATAA

Upstream 100 bases:

>100_bases
GTGGCCTGTTTTGCTATCTACCTTCTTTTCGTCTGATTTTGATACTGTGTTACGATAACTTCGTTATTATCCGTTAACGC
ATTTTCCCAGAAAGAGCCTT

Downstream 100 bases:

>100_bases
TGCCACTTTAGTGAAGCAGATCGCATTATAAGCTTTCTGTATGGGGTGTTGCTTAATTGATCTGGTATAACAGGTATAAA
GGTATATCGTTTATCAGACA

Product: transcriptional regulator NanR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKG
LVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLD
NNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQS
HLNSVSATWHAFGQTTHKKK

Sequences:

>Translated_260_residues
MNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKG
LVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLD
NNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQS
HLNSVSATWHAFGQTTHKKK
>Mature_260_residues
MNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKG
LVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLD
NNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQS
HLNSVSATWHAFGQTTHKKK

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=260, Percent_Identity=97.3076923076923, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1789353, Length=232, Percent_Identity=22.8448275862069, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29244; Mature: 29244

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMA
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
FFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAH
HHHCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
FEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHCC
GNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
HLNSVSATWHAFGQTTHKKK
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMA
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
FFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAH
HHHCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
FEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHCC
GNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
HLNSVSATWHAFGQTTHKKK
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA