Click here to switch to the map view.

The map label for this gene is hexR [H]

Identifier: 218550364

GI number: 218550364

Start: 3130505

End: 3131410

Strand: Direct

Name: hexR [H]

Synonym: EFER_3056

Alternate gene names: 218550364

Gene position: 3130505-3131410 (Clockwise)

Preceding gene: 218550362

Following gene: 218550368

Centisome position: 68.22

GC content: 52.65

Gene sequence:

>906_bases
ATGGTACAAAGTACCAATTGTCTTCGAATCAGTGATACTCCCATGGCTTATAGCATCGATATCATCTCCTGTATTACCGA
ACGGTTTATGGCGTTAACCGCCACTGAAAAGCGTATCGCACAATTTATTCTTGATGATGTCCCCGCCGCGGTGGAACTGC
CCATTGCTGAGCTGGCACGGTTAACGCAAACCAGTCAGGCGTCGGTGACGCGTTTTGCCCGTGCTCTGGGGTGTAAAGAT
GTCCGCGAGCTGAAAGTCAAACTGGCGCAGTCACTGGCTATCGGGCAGCGATTTATTCTCGATGTACCGGATCTTGACGG
TGTTCAGGGGATCTACGAATCAATTATCAGCGTGCTGGAAACGCATCGTCGTTCGCTGGATATGAACGCCATCAGCCAGG
CTGTAAGCTGGTTAAGTCAGGCGCGGCAAATTCTTGCATTGGGAACTGGCGGCGGTTCCACCATCTGTTCACAGGAGATT
CAGTACCGTTTATTCCGTCTGGGGCTACCTGTGGTTAGTCAGAATGATGCCCTGATGATGAGAATGATGTGCTCGGCAGT
GATGCCGCAGGATGTGGTGATTGTGCTGTCGCTGGGCGGTTATACACCGGAAATCATCGAAAGTGCGGCAATCGCCCGTC
AGTATGGCGCGCGTGTTATTGCCATTACGCCAGCACAAACACCGCTGGCGGAACAGGTGGATCTGGTATTGCCGTTACTG
GTTCAGGAAAGTGATTACATCTTTAAGCCCACCCCTTCCCGCTACGCGATGTTAGCCATGGTCGATGTACTGGCAACAGA
ACTGGCAATGGCAAATAAAGCGCAGGCGAAAGATCGCCTGCGGCGGATAAAACTGGTGTTAGACAGCCACCGTGGGGGCG
CTAACCGCCAGCCACTTGGCGATTAG

Upstream 100 bases:

>100_bases
CCTGAGACGAAAAAACTTTATGTTTTGGCACGTTCAAAAGGCGGATTTTATCGCTGTCAGCCTGCGTTTTTAGCGATGTC
ACACTCTGTCGCGGCTGTTT

Downstream 100 bases:

>100_bases
CATTGTCGGTTATGCTTCTTCAGGTTTGGTGATCACGACACTCTGGTTTTCACGCTCATTGGTGATAATAGCCAAAGCTT
CTTCCCGGCTGACCTGACTT

Product: transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MVQSTNCLRISDTPMAYSIDIISCITERFMALTATEKRIAQFILDDVPAAVELPIAELARLTQTSQASVTRFARALGCKD
VRELKVKLAQSLAIGQRFILDVPDLDGVQGIYESIISVLETHRRSLDMNAISQAVSWLSQARQILALGTGGGSTICSQEI
QYRLFRLGLPVVSQNDALMMRMMCSAVMPQDVVIVLSLGGYTPEIIESAAIARQYGARVIAITPAQTPLAEQVDLVLPLL
VQESDYIFKPTPSRYAMLAMVDVLATELAMANKAQAKDRLRRIKLVLDSHRGGANRQPLGD

Sequences:

>Translated_301_residues
MVQSTNCLRISDTPMAYSIDIISCITERFMALTATEKRIAQFILDDVPAAVELPIAELARLTQTSQASVTRFARALGCKD
VRELKVKLAQSLAIGQRFILDVPDLDGVQGIYESIISVLETHRRSLDMNAISQAVSWLSQARQILALGTGGGSTICSQEI
QYRLFRLGLPVVSQNDALMMRMMCSAVMPQDVVIVLSLGGYTPEIIESAAIARQYGARVIAITPAQTPLAEQVDLVLPLL
VQESDYIFKPTPSRYAMLAMVDVLATELAMANKAQAKDRLRRIKLVLDSHRGGANRQPLGD
>Mature_301_residues
MVQSTNCLRISDTPMAYSIDIISCITERFMALTATEKRIAQFILDDVPAAVELPIAELARLTQTSQASVTRFARALGCKD
VRELKVKLAQSLAIGQRFILDVPDLDGVQGIYESIISVLETHRRSLDMNAISQAVSWLSQARQILALGTGGGSTICSQEI
QYRLFRLGLPVVSQNDALMMRMMCSAVMPQDVVIVLSLGGYTPEIIESAAIARQYGARVIAITPAQTPLAEQVDLVLPLL
VQESDYIFKPTPSRYAMLAMVDVLATELAMANKAQAKDRLRRIKLVLDSHRGGANRQPLGD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=278, Percent_Identity=34.1726618705036, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI87082369, Length=270, Percent_Identity=22.962962962963, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788767, Length=271, Percent_Identity=25.830258302583, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32962; Mature: 32962

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQSTNCLRISDTPMAYSIDIISCITERFMALTATEKRIAQFILDDVPAAVELPIAELAR
CCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHH
LTQTSQASVTRFARALGCKDVRELKVKLAQSLAIGQRFILDVPDLDGVQGIYESIISVLE
HHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHH
THRRSLDMNAISQAVSWLSQARQILALGTGGGSTICSQEIQYRLFRLGLPVVSQNDALMM
HHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCEECCCHHHHH
RMMCSAVMPQDVVIVLSLGGYTPEIIESAAIARQYGARVIAITPAQTPLAEQVDLVLPLL
HHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHH
VQESDYIFKPTPSRYAMLAMVDVLATELAMANKAQAKDRLRRIKLVLDSHRGGANRQPLG
HCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
D
C
>Mature Secondary Structure
MVQSTNCLRISDTPMAYSIDIISCITERFMALTATEKRIAQFILDDVPAAVELPIAELAR
CCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHH
LTQTSQASVTRFARALGCKDVRELKVKLAQSLAIGQRFILDVPDLDGVQGIYESIISVLE
HHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHH
THRRSLDMNAISQAVSWLSQARQILALGTGGGSTICSQEIQYRLFRLGLPVVSQNDALMM
HHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCEECCCHHHHH
RMMCSAVMPQDVVIVLSLGGYTPEIIESAAIARQYGARVIAITPAQTPLAEQVDLVLPLL
HHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHH
VQESDYIFKPTPSRYAMLAMVDVLATELAMANKAQAKDRLRRIKLVLDSHRGGANRQPLG
HCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 1704005; 7567469 [H]