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The map label for this gene is ygjG [H]

Identifier: 218550333

GI number: 218550333

Start: 3095512

End: 3096918

Strand: Direct

Name: ygjG [H]

Synonym: EFER_3025

Alternate gene names: 218550333

Gene position: 3095512-3096918 (Clockwise)

Preceding gene: 218550331

Following gene: 218550334

Centisome position: 67.46

GC content: 54.37

Gene sequence:

>1407_bases
GTGATACGCGAGCCACCGGAGCATATTTTGAACAGGTTACCTTCGAGCGCATCGGCTTTAGCGTGCAGCGCCCACGCCCT
TAATCTCATAGAGAAACAAACACTTGATCATGAGGAGATGAAAGCACTAAACCGGGAGGTGATTGAATACTTTAAAGAGC
ATGTCAATCCGGGATTTTTAGAGTATCGCAAATCTGTTACCGCTGGCGGGGATTACGGAGCCGTAGAGTGGCAAGCGGGA
GGTTTAAATACGCTTGTCGACACCCAGGGACAGGAGTTTATCGACTGCCTGGGAGGTTTTGGAATTTTCAACGTGGGGCA
CCGTAATCCAGTTGTGGTTTCCGCCGTACAGAATCAACTTGCGAAACAACCGCTGCACAGCCAGGAACTGCTTGATCCAT
TACGGGCGATGCTGGCAAAAACACTTGCTGCACTGACGCCCGGTAAACTGAAATACAGCTTCTTTTGTAATAGCGGCACC
GAGTCCGTGGAAGCGGCACTGAAACTGGCGAAAGCGTACCAGTCACCGCGCGGTAAGTTTACCTTTATAGCCACCAGCGG
CGCGTTCCATGGTAAATCGCTGGGCGCACTGTCGGCCACGGCAAAATCGACCTTCCGCAAGCCGTTTATGCCGTTGCTGC
CGGGTTTCCGTCATGTACCGTTTGGTCATATCGAGGCCATGCGTACTGCTCTTAGCGAGTGCAAAAAAACCGGTGACGAT
GTTGCCGCAGTGATCCTCGAGCCGATTCAGGGCGAAGGTGGCGTCATTCTGCCGCCGCCAGGTTATCTCACCGCTGTGCG
TAAGCTGTGTGATGAGTTTGGCGCCCTGATGATCCTCGATGAAGTGCAAACCGGTATGGGGCGCACGGGCAAAATGTTCG
CCTGCGAGCATGAGAACGTGCAGCCGGATATCCTCTGCCTTGCCAAAGCGCTCGGCGGCGGCGTAATGCCAATTGGCGCA
ACCATCGCCACCGAAGAGGTGTTCTCGGTGCTGTTCGATAACCCGTTCCTGCACACCACCACCTTTGGCGGCAACCCGCT
GGCCTGTGCGGCAGCGCTGGCGACCATCAATGTGTTGCTGGAGCAGAACTTACCGGCTCAGGCTGAACAGAAAGGCGACA
TGCTGCTGGACGGTTTCCGTCAACTGGCGCGGGAATATCCCGATCTGGTACAGGAAGCGCGTGGCAAAGGGATGTTGATG
GCGATTGAATTTGTCGATAACGAAATCGGCTACAACTTTGCCAGCGAGATGTTCCGCCAGCGAGTACTGGTTGCCGGAAC
ACTCAACAACGCTAAAACGATCCGTATTGAACCACCACTGACACTGACCATTGAACAGTGTGAACTGGTCATCAAAGCGG
CACGAAAAGCGCTGGCCGCCATGCGGGTAAGTGTCGAAGAAGCATAA

Upstream 100 bases:

>100_bases
ATTAAATGTTGCAACAAAGTATCTTTTTAAGCTGTTTATCCCGATTTTCACGATCACAACCGGAGTGGCGCAATCCCTGC
AATACTTAAATCGGTATCAT

Downstream 100 bases:

>100_bases
TTCAACCCATTATCGGGCCAGAACTTATCACCCGGCCCGATAATTCTCCCCCAGCCCTAACGCTTCGTCTCCTCGCAAAA
CTGCATTTTAGTCACGACTG

Product: putrescine--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Putrescine--2-oxoglutaric acid transaminase; PAT; PATase [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MIREPPEHILNRLPSSASALACSAHALNLIEKQTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAG
GLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGT
ESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGHIEAMRTALSECKKTGDD
VAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGA
TIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLM
AIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA

Sequences:

>Translated_468_residues
MIREPPEHILNRLPSSASALACSAHALNLIEKQTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAG
GLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGT
ESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGHIEAMRTALSECKKTGDD
VAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGA
TIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLM
AIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
>Mature_468_residues
MIREPPEHILNRLPSSASALACSAHALNLIEKQTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAG
GLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGT
ESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGHIEAMRTALSECKKTGDD
VAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGA
TIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLM
AIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA

Specific function: Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithi

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=33.59375, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI284507298, Length=312, Percent_Identity=35.8974358974359, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI13994255, Length=463, Percent_Identity=30.6695464362851, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI37574042, Length=408, Percent_Identity=27.9411764705882, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI226442705, Length=408, Percent_Identity=27.6960784313726, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI226442709, Length=388, Percent_Identity=28.0927835051546, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=26.9607843137255, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI188536080, Length=433, Percent_Identity=23.7875288683603, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38679950, Length=433, Percent_Identity=23.7875288683603, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38679946, Length=433, Percent_Identity=23.7875288683603, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI145693181, Length=459, Percent_Identity=98.9106753812636, Blast_Score=932, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=369, Percent_Identity=34.6883468834688, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1789759, Length=325, Percent_Identity=36.9230769230769, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=35.0125944584383, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1789016, Length=338, Percent_Identity=34.3195266272189, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1786991, Length=394, Percent_Identity=31.2182741116751, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=29.3413173652695, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=369, Percent_Identity=33.3333333333333, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI25144274, Length=260, Percent_Identity=38.0769230769231, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI32564660, Length=425, Percent_Identity=28.2352941176471, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=419, Percent_Identity=26.7303102625298, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=435, Percent_Identity=22.7586206896552, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324432, Length=387, Percent_Identity=35.4005167958656, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6323470, Length=390, Percent_Identity=30.7692307692308, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6324386, Length=336, Percent_Identity=29.4642857142857, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321456, Length=429, Percent_Identity=23.5431235431235, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=34.025974025974, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=31.6176470588235, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI28574759, Length=449, Percent_Identity=28.5077951002227, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI161085790, Length=456, Percent_Identity=28.5087719298246, Blast_Score=168, Evalue=8e-42,
Organism=Drosophila melanogaster, GI281366494, Length=310, Percent_Identity=26.1290322580645, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24667139, Length=310, Percent_Identity=26.1290322580645, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24667143, Length=310, Percent_Identity=26.1290322580645, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR017747
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.82 [H]

Molecular weight: Translated: 50685; Mature: 50685

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREPPEHILNRLPSSASALACSAHALNLIEKQTLDHEEMKALNREVIEYFKEHVNPGFL
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHH
EYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQL
HHHHHHCCCCCCCCEEEECCCCCHHHCCCCHHHHHHHCCCCEEECCCCCCEEHHHHHHHH
AKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKF
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCE
TFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGHIEAMRTALSECKKTGDD
EEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCH
VAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENV
HHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHCCEEEEHHHHHCCCCCCCEEEECCCCC
QPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLL
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
EQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQ
HCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
RVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
HHHEEEECCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIREPPEHILNRLPSSASALACSAHALNLIEKQTLDHEEMKALNREVIEYFKEHVNPGFL
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHH
EYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQL
HHHHHHCCCCCCCCEEEECCCCCHHHCCCCHHHHHHHCCCCEEECCCCCCEEHHHHHHHH
AKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKF
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCE
TFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGHIEAMRTALSECKKTGDD
EEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCH
VAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENV
HHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHCCEEEEHHHHHCCCCCCCEEEECCCCC
QPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLL
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
EQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQ
HCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
RVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
HHHEEEECCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA