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The map label for this gene is envY [H]

Identifier: 218550239

GI number: 218550239

Start: 2999699

End: 3000526

Strand: Direct

Name: envY [H]

Synonym: EFER_2931

Alternate gene names: 218550239

Gene position: 2999699-3000526 (Clockwise)

Preceding gene: 218550233

Following gene: 218550240

Centisome position: 65.37

GC content: 42.03

Gene sequence:

>828_bases
TTGTTGACCTGTTCTCGTGAAACGAGAAAGTCATTTAAGAAAATTTATCCGCCTCAGGAGTATGGTATGCGCCTAAGTAG
TAGCACGCCTTGTGTGGTGATCCTCACGAAGAAAAAGGTTGAGCTTAAAATCAATGAACACTCCCCTATGATCCTCCCGG
AAAATAATCTGACCGTCATTGCCTGCAATAATAACAATATTGAATTCTCCTCAATGAGCAACACGATGGTGGTGCATATC
AGCATGGAGGTAATCAATGATTATCTCCTCTTTCTCAATAAAAATTTAACCTGCGTTAAACCATGGCCACGACAGAAACT
ACCGCTCATTTCCTGCCATAGCCGTACACCCGAAGTATTTGGCCTGGTGTCGTATCTTAATCAGGAAGAAAAAACGACGC
CTTGCGAAATCGCCCTTAACCGCTCACTACTTTTTACTGTGCTTTCGAACTTTCTTGAACATAGCGGATTCATCGCGCTG
CTTATGTATATGTTGCGCAGCAGCGTGCGTGACAGCGTTTGCCGGATTATTCAAAGTGATATTAAGCATTACTGGAGCCT
GCGGCAAATCGCCAGCATTCTTTGCCTCAGCCCGAGTTTACTTAAAAAGAAGTTAAAAAACGAAAGTACCAGTTATAGCC
AGATCATTACCGAGTGCCGAATGCGTTATGCCAGTAAGCAACTATTAATGGATGACAAAAATATTGCTCAAATATCACAA
ATGTGCGGCTATAACAGTACGTCTTATTTTATTTCCGTATTTAAATCTTTTTATGGCGTAACGCCAATGCATTATATTGC
TGAGCATCGCCAGCATGTAATGCCCTGA

Upstream 100 bases:

>100_bases
AAGGGATAAAGTGATGAAGATTTCGCCATCCATAAGAAATGCTAACGTAAAGAGATAAATAACAGGCTATGGAATAAGGG
GAAGTACTGATTCGTGCTTA

Downstream 100 bases:

>100_bases
TCTGCCACCTGACAGCAGGCAATGAACTGCTACACTGCTTCAACACCACCACTCACAAGGCAGGTCATTATGGCAGACAA
TACTTATCAACCCGCGAAAG

Product: envelope protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MLTCSRETRKSFKKIYPPQEYGMRLSSSTPCVVILTKKKVELKINEHSPMILPENNLTVIACNNNNIEFSSMSNTMVVHI
SMEVINDYLLFLNKNLTCVKPWPRQKLPLISCHSRTPEVFGLVSYLNQEEKTTPCEIALNRSLLFTVLSNFLEHSGFIAL
LMYMLRSSVRDSVCRIIQSDIKHYWSLRQIASILCLSPSLLKKKLKNESTSYSQIITECRMRYASKQLLMDDKNIAQISQ
MCGYNSTSYFISVFKSFYGVTPMHYIAEHRQHVMP

Sequences:

>Translated_275_residues
MLTCSRETRKSFKKIYPPQEYGMRLSSSTPCVVILTKKKVELKINEHSPMILPENNLTVIACNNNNIEFSSMSNTMVVHI
SMEVINDYLLFLNKNLTCVKPWPRQKLPLISCHSRTPEVFGLVSYLNQEEKTTPCEIALNRSLLFTVLSNFLEHSGFIAL
LMYMLRSSVRDSVCRIIQSDIKHYWSLRQIASILCLSPSLLKKKLKNESTSYSQIITECRMRYASKQLLMDDKNIAQISQ
MCGYNSTSYFISVFKSFYGVTPMHYIAEHRQHVMP
>Mature_275_residues
MLTCSRETRKSFKKIYPPQEYGMRLSSSTPCVVILTKKKVELKINEHSPMILPENNLTVIACNNNNIEFSSMSNTMVVHI
SMEVINDYLLFLNKNLTCVKPWPRQKLPLISCHSRTPEVFGLVSYLNQEEKTTPCEIALNRSLLFTVLSNFLEHSGFIAL
LMYMLRSSVRDSVCRIIQSDIKHYWSLRQIASILCLSPSLLKKKLKNESTSYSQIITECRMRYASKQLLMDDKNIAQISQ
MCGYNSTSYFISVFKSFYGVTPMHYIAEHRQHVMP

Specific function: Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins ompF and ompC and the lambda receptor, lamB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786778, Length=252, Percent_Identity=68.2539682539683, Blast_Score=351, Evalue=4e-98,
Organism=Escherichia coli, GI1790557, Length=252, Percent_Identity=53.1746031746032, Blast_Score=281, Evalue=5e-77,
Organism=Escherichia coli, GI1789933, Length=210, Percent_Identity=37.6190476190476, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786776, Length=93, Percent_Identity=47.3118279569892, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787776, Length=149, Percent_Identity=39.5973154362416, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789932, Length=153, Percent_Identity=37.9084967320261, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 31760; Mature: 31760

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTCSRETRKSFKKIYPPQEYGMRLSSSTPCVVILTKKKVELKINEHSPMILPENNLTVI
CCCCCHHHHHHHHHCCCCHHHCCEECCCCCEEEEEECCEEEEEECCCCCEEECCCCEEEE
ACNNNNIEFSSMSNTMVVHISMEVINDYLLFLNKNLTCVKPWPRQKLPLISCHSRTPEVF
EECCCCEEEEECCCEEEEEEEHHHHHHHHHHHCCCCEEECCCCCCCCCEEECCCCCHHHH
GLVSYLNQEEKTTPCEIALNRSLLFTVLSNFLEHSGFIALLMYMLRSSVRDSVCRIIQSD
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IKHYWSLRQIASILCLSPSLLKKKLKNESTSYSQIITECRMRYASKQLLMDDKNIAQISQ
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MCGYNSTSYFISVFKSFYGVTPMHYIAEHRQHVMP
HHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTCSRETRKSFKKIYPPQEYGMRLSSSTPCVVILTKKKVELKINEHSPMILPENNLTVI
CCCCCHHHHHHHHHCCCCHHHCCEECCCCCEEEEEECCEEEEEECCCCCEEECCCCEEEE
ACNNNNIEFSSMSNTMVVHISMEVINDYLLFLNKNLTCVKPWPRQKLPLISCHSRTPEVF
EECCCCEEEEECCCEEEEEEEHHHHHHHHHHHCCCCEEECCCCCCCCCEEECCCCCHHHH
GLVSYLNQEEKTTPCEIALNRSLLFTVLSNFLEHSGFIALLMYMLRSSVRDSVCRIIQSD
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IKHYWSLRQIASILCLSPSLLKKKLKNESTSYSQIITECRMRYASKQLLMDDKNIAQISQ
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MCGYNSTSYFISVFKSFYGVTPMHYIAEHRQHVMP
HHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2536924; 8905232; 9278503 [H]