Click here to switch to the map view.

The map label for this gene is yggW [H]

Identifier: 218550202

GI number: 218550202

Start: 2958703

End: 2959839

Strand: Direct

Name: yggW [H]

Synonym: EFER_2894

Alternate gene names: 218550202

Gene position: 2958703-2959839 (Clockwise)

Preceding gene: 218550201

Following gene: 218550203

Centisome position: 64.48

GC content: 53.21

Gene sequence:

>1137_bases
ATGGTTAAATTACCGCCGCTGAGTCTCTACATTCACATCCCGTGGTGCGTGCAGAAATGCCCGTACTGCGATTTCAACTC
TCACGCGTTGAAAGGAGAAGTGCCGCACGACGATTATGTTCAGCATCTGCTTAACGATCTGGACAACGATGTGGCTTACG
CTCAGGGCCGTGAAGTGCAGACAATCTTTATTGGCGGTGGCACGCCGAGCCTGCTTTCCGGCCCGGCGATGCAAACGCTG
CTGGACGGCGTGCGTGCGCGTTTGCCGCTGGCAGCGGATGCAGAAATTACTATGGAAGCGAACCCAGGCACGGTAGAAGC
CGATCGCTTTGTCGATTATCAGCGTGCTGGTGTAAACCGCATCTCTATTGGTGTGCAGAGTTTTAGTGAAGAAAAGCTAA
AACGACTTGGACGTATTCATGGCCCGCAAGAAGCGAAACGGGCGGCAAATCTGGCAAGCGGGCTGGGGCTGCGTAGTTTT
AACCTCGATTTGATGCATGGGTTGCCTGATCAATCACTGGAAGAGGCGCTTGGCGATCTACGCCAGGCCATTGAACTGAA
TCCGCCGCATCTTTCCTGGTATCAACTGACCATCGAACCTAATACGTTGTTTGGCTCACGCCCTCCTGTACTGCCGGACG
ACGATGCATTGTGGGATATCTTCGAGCAAGGGCATCAGTTATTAACGGCTGCGGGTTATCAGCAATATGAAACCTCCGCT
TACGCCAAACCGGGTTATCAGTGCCAGCACAATCTCAACTACTGGCGATTTGGCGACTACATCGGCATCGGCTGCGGGGC
GCACGGCAAAGTCACCTTCCCGGATGGGCGCATTCTGCGCACCACCAAAACGCGGCACCCGCGTGGTTTTATGCAGGGGC
GTTATCTGGAAAGCCTGCGTGATGTCGAAGCCGCAGATAAGCCGTTTGAGTTCTTTATGAACCGCTTTCGCTTGCTGGAG
GCCGCACCACGCGCAGAGTTTAGTGCGTATACCGGGCTTTGCGAAGATGTGATTCGCCCACAGTTAGACGAGGCTATCGC
TCAGGGTTATCTCACAGAATGTGCGGATTACTGGCAGATAACCGAGCACGGTAAATTATTCTTAAACTCACTTCTTGAAT
TATTCCTCGCTGAGTAA

Upstream 100 bases:

>100_bases
CCTTCCGAAGGTAAAACCGCTGCCGAACTGACCCGCGAAGAAAAGAGCGCTATTTCCCACCGTGGTCAGGCATTGAAACT
GCTGTTGGACGCTTTACGAA

Downstream 100 bases:

>100_bases
TCATTAATGCGCCTGCGGGCGCATTAATCACTTCTTTTATCCCCCCGTTAATTAACTTCGGCAAAAATATATTTCTTACT
GAATAAATATCGACGATATT

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQTIFIGGGTPSLLSGPAMQTL
LDGVRARLPLAADAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAANLASGLGLRSF
NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
YAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESLRDVEAADKPFEFFMNRFRLLE
AAPRAEFSAYTGLCEDVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE

Sequences:

>Translated_378_residues
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQTIFIGGGTPSLLSGPAMQTL
LDGVRARLPLAADAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAANLASGLGLRSF
NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
YAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESLRDVEAADKPFEFFMNRFRLLE
AAPRAEFSAYTGLCEDVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE
>Mature_378_residues
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQTIFIGGGTPSLLSGPAMQTL
LDGVRARLPLAADAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAANLASGLGLRSF
NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
YAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESLRDVEAADKPFEFFMNRFRLLE
AAPRAEFSAYTGLCEDVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=284, Percent_Identity=35.9154929577465, Blast_Score=173, Evalue=2e-43,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=98.4126984126984, Blast_Score=774, Evalue=0.0,
Organism=Escherichia coli, GI87082341, Length=244, Percent_Identity=33.1967213114754, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42472; Mature: 42472

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQ
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCEEE
TIFIGGGTPSLLSGPAMQTLLDGVRARLPLAADAEITMEANPGTVEADRFVDYQRAGVNR
EEEECCCCCHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCE
ISIGVQSFSEEKLKRLGRIHGPQEAKRAANLASGLGLRSFNLDLMHGLPDQSLEEALGDL
EEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECHHHHCCCCCHHHHHHHHHH
RQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
YAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESLR
CCCCCCCCCCCCCEEEECCEEEECCCCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHH
DVEAADKPFEFFMNRFRLLEAAPRAEFSAYTGLCEDVIRPQLDEAIAQGYLTECADYWQI
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEHGKLFLNSLLELFLAE
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQ
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCEEE
TIFIGGGTPSLLSGPAMQTLLDGVRARLPLAADAEITMEANPGTVEADRFVDYQRAGVNR
EEEECCCCCHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCE
ISIGVQSFSEEKLKRLGRIHGPQEAKRAANLASGLGLRSFNLDLMHGLPDQSLEEALGDL
EEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECHHHHCCCCCHHHHHHHHHH
RQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
YAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESLR
CCCCCCCCCCCCCEEEECCEEEECCCCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHH
DVEAADKPFEFFMNRFRLLEAAPRAEFSAYTGLCEDVIRPQLDEAIAQGYLTECADYWQI
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEHGKLFLNSLLELFLAE
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]