Click here to switch to the map view.

The map label for this gene is hflC [H]

Identifier: 218550176

GI number: 218550176

Start: 2931588

End: 2932505

Strand: Direct

Name: hflC [H]

Synonym: EFER_2866

Alternate gene names: 218550176

Gene position: 2931588-2932505 (Clockwise)

Preceding gene: 218550163

Following gene: 218550178

Centisome position: 63.89

GC content: 48.04

Gene sequence:

>918_bases
ATGATTCACATGAAAGCTCCAGTTTCTTTTCCTTCGCTTCGCCCACAAAAATTTATTGGCATTACTGTTGGCGTACTGGC
AGTCATTACGCTGCCATTTCTTTCGTATTACACCGTAAACGAAGGCGAACGCGGCATTTTATTGCGCTATGGCAAGATCG
TTAAAGTTGCCGAACCCGGTCTTGGATTCAAAATTCCCTTTATGGAAAGTGTCGAGAAAATCTCCACACGTAACCAGGCT
GTAGTGTATCAGGGATTACAAGCCTACAGCCGTGACCAGCAACCAGCACAAATGACCGTGTCGGTTAGTTTTCATATTAA
GCCTTCAGAAGCTGGCGCAGTTTATACTACCTACAACACTATAGAATCTTTAAAAGAGCGTCTGATCGTCCGCCAGCTGC
CAACCCAACTGGAGAACGTTTTCGGGCAATATACAGCCATTAGCGCGGTACAAGATCGTACAAAACTGGTGCAGGATCTG
CAAAACGCGATGCGCAAAGCGGTTGTTGGCCCGGTAGTGATAGACGGTGTTCAGATCGAGAACATTGATTTTTCAGATGC
TTATGAGAAATCAATTGAAGACCGAATGAAAGCGGAAGTTGCAATTGCTACTCGCAGGCAAAATCTTGAGACGGAAAAAA
TCCAGGCGCAAATTGCGGTAACTCAGGCCCAGGCTGAAGCTGACAGTAAACTGGCGGCAGCCAAAGCAGAAGCTGAGACC
ATTCGCGTAAAAGGCGCGGCAGAAGCGGAAACTATTCGTTTGAAAAGTGCGGCTGAAGCAGAAGCTATCCGCCTGCGCGG
GGAAGCCCTGCGAGATAATCCAGGCCTTGTTGCCCTTACCACTGCAGAGCGTTGGGACGGTAAGCTACCCGATACCATGA
TCCCCGGCAGTACAGTTCCGTTTATCTCTACTAAGTAA

Upstream 100 bases:

>100_bases
TATTCATCCTTTTTGGTTGCTCCTTTATGGATTCTGAATTCATGGCAACTGGCTGTTCTCCTTTCATTTCGTGTGACATA
TTCCCTTTCTTTGCTCACGG

Downstream 100 bases:

>100_bases
AAAAAGGGCCGCTTTCGCGGCCCTTCTCACAATGCATCTTACCGATTACAGCAACGCTTTTGCTTTCGCAACAACGTTGT
CAACGGTGAAGCCGAACTCT

Product: membrane protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MIHMKAPVSFPSLRPQKFIGITVGVLAVITLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGFKIPFMESVEKISTRNQA
VVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIESLKERLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDL
QNAMRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRRQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAET
IRVKGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVPFISTK

Sequences:

>Translated_305_residues
MIHMKAPVSFPSLRPQKFIGITVGVLAVITLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGFKIPFMESVEKISTRNQA
VVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIESLKERLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDL
QNAMRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRRQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAET
IRVKGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVPFISTK
>Mature_305_residues
MIHMKAPVSFPSLRPQKFIGITVGVLAVITLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGFKIPFMESVEKISTRNQA
VVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIESLKERLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDL
QNAMRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRRQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAET
IRVKGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVPFISTK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=301, Percent_Identity=25.2491694352159, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 33523; Mature: 33523

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHMKAPVSFPSLRPQKFIGITVGVLAVITLPFLSYYTVNEGERGILLRYGKIVKVAEPG
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCEEEEECCC
LGFKIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNT
CCEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEHHH
IESLKERLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDLQNAMRKAVVGPVVIDGVQIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEE
NIDFSDAYEKSIEDRMKAEVAIATRRQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAET
CCCCHHHHHHHHHHHHHHHHHEEHHHCCCCHHHHHEEHEEEHHHHHHHHHHHHHHCCCCE
IRVKGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVP
EEEECCCCCCEEEECCCCHHHHHHHCCHHHCCCCCEEEEEECHHCCCCCCCCCCCCCCCC
FISTK
CEECC
>Mature Secondary Structure
MIHMKAPVSFPSLRPQKFIGITVGVLAVITLPFLSYYTVNEGERGILLRYGKIVKVAEPG
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCEEEEECCC
LGFKIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNT
CCEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEHHH
IESLKERLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDLQNAMRKAVVGPVVIDGVQIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEE
NIDFSDAYEKSIEDRMKAEVAIATRRQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAET
CCCCHHHHHHHHHHHHHHHHHEEHHHCCCCHHHHHEEHEEEHHHHHHHHHHHHHHCCCCE
IRVKGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVP
EEEECCCCCCEEEECCCCHHHHHHHCCHHHCCCCCEEEEEECHHCCCCCCCCCCCCCCCC
FISTK
CEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]