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The map label for this gene is visC [H]

Identifier: 218550154

GI number: 218550154

Start: 2909890

End: 2911092

Strand: Reverse

Name: visC [H]

Synonym: EFER_2843

Alternate gene names: 218550154

Gene position: 2911092-2909890 (Counterclockwise)

Preceding gene: 218550155

Following gene: 218550153

Centisome position: 63.44

GC content: 55.44

Gene sequence:

>1203_bases
ATGCAAAGTGTTGATGTAGCCATTGTTGGCGGCGGCATGGTGGGGCTGGCGGTTGCCTGCGGCTTACAGGGGAGCGGCTT
ACGCGTTGCCGTACTGGAGCAGCGCGTACCGGAACCTCTGGCGGCGGATGCACCACCACAACTGCGCGTTTCGGCTATCA
ATGCCGCCAGCGAAAAATTACTCTCCCGTCTTGGCGTCTGGCAGGAGATCCTCTCCCGCAGGGCCAGTTGCTATCACGGC
ATGGAAGTGTGGGACAAAGACAGTTTTGGTCACATTTCGTTTGACGATCAAAGCATGGGCTATAGCCATCTTGGGCATAT
CGTTGAAAATTCAGTCATTCACTACGCGCTGTGGAACAAAGCACAGCAGTCGTCAGATATCAGCCTGTTAGCCCCTGCAG
AATTACAGCAGGTCGCCTGGGGAGAGAACGAAACCTTCCTGACGCTGAAAGACGGCAGTATGTTAACGGCGCGTCTGGTA
ATTGGCGCAGACGGCGCTAATTCCTGGTTGCGCAACAAAGCCGATATTCCGCTGACTTTCTGGGATTATCAGCATCACGC
GCTGGTGGCGACCATTCGCACGGAAGAACCGCATGATGCGGTGGCGCGACAGGTTTTCCATGGCGGAGGCATTCTGGCCT
TTTTGCCGCTTAGCGATCCGCATCTTTGCTCAATTGTCTGGTCACTGTTCCCAGAGGAAGCACAGCGGATGCAGCAGGCA
GGCGAAGACGAATTTAATCGCGAGTTAAATATCGCTTTTGATAATCGCCTGGGCTTATGCAAGGTTGAGAGTGAACGCCT
GGTGTTCCCGCTGACTGGGCGTTATGCGCGCCAGTTTGCCGCGCACCGTCTGGCGCTGGTGGGCGACGCCGCGCATACCA
TTCACCCGTTGGCGGGGCAGGGGGTGAATCTCGGCTTTATGGATGCTGCAGAGCTGATTGCTGAACTGAAACGGTTGCAT
CGTCAGGGTAAAGACATCGGGCAGTACATTTACCTGCGTCGCTATGAGCGTAGCCGCAAGCACAGTGCGGCGCTGATGCT
GGCAGGTATGCAGGGATTCCGCGATCTGTTTTCCGGGGCTAATCCGGCGAAAAAACTGCTGCGTGATATTGGTCTGAAAC
TGGCCGACACGCTTCCTGGCGTTAAACCACAACTTATCCGTCAGGCAATGGGATTAAACGATTTGCCTGAATGGCTGCGC
TAA

Upstream 100 bases:

>100_bases
GGGCTGATGGCAATGGAATTATTCACTCCGGCACGCGATGTGCTGGCGCAGCGCACCCTCGGTTGGGTGGCGCGTTGAAG
GCGGTTTTAAGGAATAAACA

Downstream 100 bases:

>100_bases
AAATTTCTCTTCTGCTGTTTATTTGATACCCATCACACTTTCATCTCCCGGTTTTTTCGCCGGGAGATTTTCCTCATTTG
AAATAAACTAATTTCACCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLSRLGVWQEILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDISLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGGGILAFLPLSDPHLCSIVWSLFPEEAQRMQQA
GEDEFNRELNIAFDNRLGLCKVESERLVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGANPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR

Sequences:

>Translated_400_residues
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLSRLGVWQEILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDISLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGGGILAFLPLSDPHLCSIVWSLFPEEAQRMQQA
GEDEFNRELNIAFDNRLGLCKVESERLVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGANPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
>Mature_400_residues
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLSRLGVWQEILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDISLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGGGILAFLPLSDPHLCSIVWSLFPEEAQRMQQA
GEDEFNRELNIAFDNRLGLCKVESERLVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGANPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=381, Percent_Identity=33.3333333333333, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI32967307, Length=347, Percent_Identity=32.8530259365994, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1789273, Length=400, Percent_Identity=96.5, Blast_Score=792, Evalue=0.0,
Organism=Escherichia coli, GI1786883, Length=392, Percent_Identity=38.7755102040816, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789274, Length=393, Percent_Identity=30.2798982188295, Blast_Score=166, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI25146631, Length=431, Percent_Identity=32.2505800464037, Blast_Score=181, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6321694, Length=458, Percent_Identity=24.6724890829694, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI19920760, Length=384, Percent_Identity=33.8541666666667, Blast_Score=178, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44205; Mature: 44205

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKL
CCCCEEEEECCCHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEHHHHHHHHHH
LSRLGVWQEILSRRASCYHGMEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNK
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHHHHHHCCEEEEHHHHH
AQQSSDISLLAPAELQQVAWGENETFLTLKDGSMLTARLVIGADGANSWLRNKADIPLTF
HCCCCCCEEECCHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCHHHCCCCCCCEEE
WDYQHHALVATIRTEEPHDAVARQVFHGGGILAFLPLSDPHLCSIVWSLFPEEAQRMQQA
ECCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCHHHHHHHHHC
GEDEFNRELNIAFDNRLGLCKVESERLVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQ
CCHHHCCEEEEEECCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCCC
GVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGA
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
CHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCCCHHHHC
>Mature Secondary Structure
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKL
CCCCEEEEECCCHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEHHHHHHHHHH
LSRLGVWQEILSRRASCYHGMEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNK
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHHHHHHCCEEEEHHHHH
AQQSSDISLLAPAELQQVAWGENETFLTLKDGSMLTARLVIGADGANSWLRNKADIPLTF
HCCCCCCEEECCHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCHHHCCCCCCCEEE
WDYQHHALVATIRTEEPHDAVARQVFHGGGILAFLPLSDPHLCSIVWSLFPEEAQRMQQA
ECCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCHHHHHHHHHC
GEDEFNRELNIAFDNRLGLCKVESERLVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQ
CCHHHCCEEEEEECCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCCC
GVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGA
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
CHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCCCHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]