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The map label for this gene is ybcS [H]

Identifier: 218550016

GI number: 218550016

Start: 2775696

End: 2776193

Strand: Reverse

Name: ybcS [H]

Synonym: EFER_2701

Alternate gene names: 218550016

Gene position: 2776193-2775696 (Counterclockwise)

Preceding gene: 218550017

Following gene: 218550015

Centisome position: 60.5

GC content: 47.79

Gene sequence:

>498_bases
ATGCCTCCATCATTACGAAAAGCTGTTGCTGCTGCTATTGGTGGCGGGGCTATTGCTATAGCATCTGTGTTAATCACTGG
CCCAAGTGGTAACGATGGTCTGGAAGGTGTGAGACATAATCCTTACAAAGACATAGTTGGTGTATGGACTGTATGTTACG
GACACACCGGAAAAGACATTATGCTCGGTAAAACGTATACCGAAGCAGAATGCAAAGCCCTCCTGAATAAAGACCTTGCC
ACTGTCGCCAGACAAATTAACCCGTACATCAAAGTCGATATACCGGAAACAACGCGCGGCGCTCTTTACTCGTTCGTCTA
CAACGTGGGTGCTGGCAATTTCAGAACATCGACGCTTCTTCGCAAAATAAACCAGGGTGATATCAAAGGCGCATGTGATC
AGCTACGGCGCTGGACATACGCTGGCGGTAAGCAATGGAAAGGTCTCATGACTCGTCGTGAGATTGAGCGTGAAATCTGT
TTGTGGGGTCAGCAATGA

Upstream 100 bases:

>100_bases
TAGGTGTGCTGGGTAGCTTGGTATTTGGCCTGCTGACGTACCTGACAAACCTTTATTTCAAGATTAAAGAAGATAAGCGC
AAGGCTGCGAGAGGTGAATA

Downstream 100 bases:

>100_bases
ACAGAGTAACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGAT
AACGCAATCGCCTACAAAGA

Product: lysozyme; DLP12 prophage

Products: NA

Alternate protein names: Endolysin; Lysis protein; Muramidase [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MPPSLRKAVAAAIGGGAIAIASVLITGPSGNDGLEGVRHNPYKDIVGVWTVCYGHTGKDIMLGKTYTEAECKALLNKDLA
TVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREIC
LWGQQ

Sequences:

>Translated_165_residues
MPPSLRKAVAAAIGGGAIAIASVLITGPSGNDGLEGVRHNPYKDIVGVWTVCYGHTGKDIMLGKTYTEAECKALLNKDLA
TVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREIC
LWGQQ
>Mature_164_residues
PPSLRKAVAAAIGGGAIAIASVLITGPSGNDGLEGVRHNPYKDIVGVWTVCYGHTGKDIMLGKTYTEAECKALLNKDLAT
VARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREICL
WGQQ

Specific function: Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity [H]

COG id: COG3772

COG function: function code R; Phage-related lysozyme (muraminidase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 24 family [H]

Homologues:

Organism=Escherichia coli, GI1786768, Length=165, Percent_Identity=96.3636363636364, Blast_Score=304, Evalue=2e-84,
Organism=Escherichia coli, GI1787836, Length=176, Percent_Identity=32.3863636363636, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002196 [H]

Pfam domain/function: PF00959 Phage_lysozyme [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 18057; Mature: 17926

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSLRKAVAAAIGGGAIAIASVLITGPSGNDGLEGVRHNPYKDIVGVWTVCYGHTGKDI
CCCHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEE
MLGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLL
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
RKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREICLWGQQ
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PPSLRKAVAAAIGGGAIAIASVLITGPSGNDGLEGVRHNPYKDIVGVWTVCYGHTGKDI
CCHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEE
MLGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLL
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
RKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREICLWGQQ
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]