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The map label for this gene is adrA [H]

Identifier: 218549953

GI number: 218549953

Start: 2708391

End: 2709590

Strand: Reverse

Name: adrA [H]

Synonym: EFER_2638

Alternate gene names: 218549953

Gene position: 2709590-2708391 (Counterclockwise)

Preceding gene: 218549954

Following gene: 218549951

Centisome position: 59.05

GC content: 49.5

Gene sequence:

>1200_bases
GTGAGACACGCAAACGCCTCACCCGAAATATCATACTTTCTCCCTCACCCCCCCTCCTATAATTTGGGAAATTTGTTTCT
AAATATTCCCAAAAAAATAATGAATGATGAAAACTTCCTTAAAAAAGCGGTCGCACCGGGTGAAGAACCACCTTCTTCAC
CTCAAAACGAACATCAACGTTCCGGGTTACGCTTTGCCCGTCGTGTGAGGCTACCAAGAGTTGTCGGTTTTGGCGGTATG
TTCTTCCCCATCGCCTCGGCGCTGGTGGAGCAACCGATCGCTGGATGGTGGTGGTTGATCCTTGTTGGCTGGTCATTCGT
TTGGCCACATCTGGCCTGGCAAATGTCCAGTCGTGCAATGGACCCCTTAAACCGTGAAATTTACAACCTAAAAACGGATG
CGATTACTGCCGGGATGTGGGTTGGCATAATGGGTGTTAACGCACTACCTTCAACGACGATGCTGATGATTATGTGCCTT
AACCTGATGGGCGCCGGAGGCATTAGGTTGTTCGTCGCCGGGCTGGTATTGATGGTAGTCGCATGTCTGGTGACGCTACA
GTTGACCGGCATCCGCGTCGCGTTTACCAGTTCGCCCCTTGAGTGGTGGCTTTCACTCCCTGTCATTGTGTTGTATCCCT
TAATTTTCGCCTGGGTCAGCTATCAGACAGCAACTAAATTGGCAGAGCATAAACGCCGTTTGCAGGTAATGAGCGCCAGA
GATGGTATGACTGGGGTATATAATCGGAGACATTGGGAAACTTTACTGTGTATTGAATTTGATCATTGCCGACGTTATCA
ACGCGATGCCACGCTGCTCATTATCGATATTGATCATTTCAAGAGCATTAACGATACCTGGGGGCATGATGTAGGTGATG
AAGCGATCCTCGCACTGACCCGCCAATTGCAAATGACGTTACGCAGTAGTGATGTAATAGGGCGCTTTGGTGGTGATGAA
TTTGCGGTGATCATGTGTGGAACGCCCGCAGAAAATGCGATTGCCGCGATGTCCAGGGTACATGAACGTCTCTCGCATTT
GCGTTTGTCTTGTGCCCCGCAAGTTATTTTACGTATCAGCGTAGGGGTAGCGCCATTAACGCCGCAAATCAGTCACTATC
GTGAATGGTTAAAATCTGCAGATATGGCGCTCTACAAAGCAAAGAGCGCCGGACGTAATCGCACCGAAGTGGCGGCCTGA

Upstream 100 bases:

>100_bases
ATACCCAGGCGACGGAACAATCACTGAAAGGTGACGACCGTAATAAATTTATGAGTGCGTGTCTGAAGAAAGCTGCATAG
ATCCCCCTTAGTGCTTACGG

Downstream 100 bases:

>100_bases
CGTCCGGCACCAGACTCAGGATTTACTGAGTTGTTCTGATTTTTCCATACACTTCGCCATAGCTTCGATCACGGCAGCAC
GGAAGCCTCGATCTTCCAGA

Product: diguanylate cyclase AdrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MRHANASPEISYFLPHPPSYNLGNLFLNIPKKIMNDENFLKKAVAPGEEPPSSPQNEHQRSGLRFARRVRLPRVVGFGGM
FFPIASALVEQPIAGWWWLILVGWSFVWPHLAWQMSSRAMDPLNREIYNLKTDAITAGMWVGIMGVNALPSTTMLMIMCL
NLMGAGGIRLFVAGLVLMVVACLVTLQLTGIRVAFTSSPLEWWLSLPVIVLYPLIFAWVSYQTATKLAEHKRRLQVMSAR
DGMTGVYNRRHWETLLCIEFDHCRRYQRDATLLIIDIDHFKSINDTWGHDVGDEAILALTRQLQMTLRSSDVIGRFGGDE
FAVIMCGTPAENAIAAMSRVHERLSHLRLSCAPQVILRISVGVAPLTPQISHYREWLKSADMALYKAKSAGRNRTEVAA

Sequences:

>Translated_399_residues
MRHANASPEISYFLPHPPSYNLGNLFLNIPKKIMNDENFLKKAVAPGEEPPSSPQNEHQRSGLRFARRVRLPRVVGFGGM
FFPIASALVEQPIAGWWWLILVGWSFVWPHLAWQMSSRAMDPLNREIYNLKTDAITAGMWVGIMGVNALPSTTMLMIMCL
NLMGAGGIRLFVAGLVLMVVACLVTLQLTGIRVAFTSSPLEWWLSLPVIVLYPLIFAWVSYQTATKLAEHKRRLQVMSAR
DGMTGVYNRRHWETLLCIEFDHCRRYQRDATLLIIDIDHFKSINDTWGHDVGDEAILALTRQLQMTLRSSDVIGRFGGDE
FAVIMCGTPAENAIAAMSRVHERLSHLRLSCAPQVILRISVGVAPLTPQISHYREWLKSADMALYKAKSAGRNRTEVAA
>Mature_399_residues
MRHANASPEISYFLPHPPSYNLGNLFLNIPKKIMNDENFLKKAVAPGEEPPSSPQNEHQRSGLRFARRVRLPRVVGFGGM
FFPIASALVEQPIAGWWWLILVGWSFVWPHLAWQMSSRAMDPLNREIYNLKTDAITAGMWVGIMGVNALPSTTMLMIMCL
NLMGAGGIRLFVAGLVLMVVACLVTLQLTGIRVAFTSSPLEWWLSLPVIVLYPLIFAWVSYQTATKLAEHKRRLQVMSAR
DGMTGVYNRRHWETLLCIEFDHCRRYQRDATLLIIDIDHFKSINDTWGHDVGDEAILALTRQLQMTLRSSDVIGRFGGDE
FAVIMCGTPAENAIAAMSRVHERLSHLRLSCAPQVILRISVGVAPLTPQISHYREWLKSADMALYKAKSAGRNRTEVAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=368, Percent_Identity=83.4239130434783, Blast_Score=644, Evalue=0.0,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=35.8490566037736, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787262, Length=255, Percent_Identity=28.6274509803922, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=36.046511627907, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI87082007, Length=208, Percent_Identity=31.25, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=29.3785310734463, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081974, Length=203, Percent_Identity=30.5418719211823, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788085, Length=182, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787541, Length=179, Percent_Identity=30.7262569832402, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787802, Length=165, Percent_Identity=29.0909090909091, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=164, Percent_Identity=28.6585365853659, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=31.0975609756098, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787056, Length=131, Percent_Identity=35.8778625954198, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788956, Length=172, Percent_Identity=26.7441860465116, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 44880; Mature: 44880

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHANASPEISYFLPHPPSYNLGNLFLNIPKKIMNDENFLKKAVAPGEEPPSSPQNEHQR
CCCCCCCCCEEEECCCCCCCCCCHHHEECCHHHCCCHHHHHHHCCCCCCCCCCCCHHHHH
SGLRFARRVRLPRVVGFGGMFFPIASALVEQPIAGWWWLILVGWSFVWPHLAWQMSSRAM
HHHHHHHHHCCCHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPLNREIYNLKTDAITAGMWVGIMGVNALPSTTMLMIMCLNLMGAGGIRLFVAGLVLMVV
CHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ACLVTLQLTGIRVAFTSSPLEWWLSLPVIVLYPLIFAWVSYQTATKLAEHKRRLQVMSAR
HHHHHHHHCCEEEEEECCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGMTGVYNRRHWETLLCIEFDHCRRYQRDATLLIIDIDHFKSINDTWGHDVGDEAILALT
CCCCHHCCCCCCCEEEEEEEHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHH
RQLQMTLRSSDVIGRFGGDEFAVIMCGTPAENAIAAMSRVHERLSHLRLSCAPQVILRIS
HHHHHHHHHCCHHEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHEE
VGVAPLTPQISHYREWLKSADMALYKAKSAGRNRTEVAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRHANASPEISYFLPHPPSYNLGNLFLNIPKKIMNDENFLKKAVAPGEEPPSSPQNEHQR
CCCCCCCCCEEEECCCCCCCCCCHHHEECCHHHCCCHHHHHHHCCCCCCCCCCCCHHHHH
SGLRFARRVRLPRVVGFGGMFFPIASALVEQPIAGWWWLILVGWSFVWPHLAWQMSSRAM
HHHHHHHHHCCCHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPLNREIYNLKTDAITAGMWVGIMGVNALPSTTMLMIMCLNLMGAGGIRLFVAGLVLMVV
CHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ACLVTLQLTGIRVAFTSSPLEWWLSLPVIVLYPLIFAWVSYQTATKLAEHKRRLQVMSAR
HHHHHHHHCCEEEEEECCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGMTGVYNRRHWETLLCIEFDHCRRYQRDATLLIIDIDHFKSINDTWGHDVGDEAILALT
CCCCHHCCCCCCCEEEEEEEHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHH
RQLQMTLRSSDVIGRFGGDEFAVIMCGTPAENAIAAMSRVHERLSHLRLSCAPQVILRIS
HHHHHHHHHCCHHEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHEE
VGVAPLTPQISHYREWLKSADMALYKAKSAGRNRTEVAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]