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The map label for this gene is cusF [H]

Identifier: 218549853

GI number: 218549853

Start: 2601905

End: 2602237

Strand: Reverse

Name: cusF [H]

Synonym: EFER_2537

Alternate gene names: 218549853

Gene position: 2602237-2601905 (Counterclockwise)

Preceding gene: 218549854

Following gene: 218549852

Centisome position: 56.71

GC content: 44.14

Gene sequence:

>333_bases
ATGAAAAAAGCACTGCAAGTCGTAATGTTCAGTCTGTTTACTGTTATTGGCTTTAATGCCCAGGCTAACGAACATCATCA
TGAAACCATGAGCGAGGCACAACCACAGGTCATTAGCGCCACCGGTGTGGTAAAAACTATTGATCTGGAAAGCAAAAAAA
TCACCATCCACCACGATCCGATTGCCGCAGTGAACTGGCCGGAGATGACCATGCGCTTTACCATCACCCCGCAGACGAAA
ATGAGTGAAATTAAAACTGGCGACAAAGTAGCGTTTAATTTTGTCCAGCAGGGCAACCTTTCTTTATTACAGGATATTAA
AGTCAGCCAGTAA

Upstream 100 bases:

>100_bases
TTACTCGACCTGAATTATGCCCGTCAGGTTAACGAAGTTTCCTTATATACCGCCCTGGGTGGCGGTTGGCAGCAATAAAT
TTTAACTCCAGGAGAGAATA

Downstream 100 bases:

>100_bases
CCCAGGTTTAATGAGATGAAAAAAATCGCGCTTATTATCGGCAGCATGATCGCGGGCGGTATTATTTCTGCGGCAGGTTT
TACCTGGTTTGCAAAGGCTG

Product: periplasmic copper-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MKKALQVVMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKTIDLESKKITIHHDPIAAVNWPEMTMRFTITPQTK
MSEIKTGDKVAFNFVQQGNLSLLQDIKVSQ

Sequences:

>Translated_110_residues
MKKALQVVMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKTIDLESKKITIHHDPIAAVNWPEMTMRFTITPQTK
MSEIKTGDKVAFNFVQQGNLSLLQDIKVSQ
>Mature_110_residues
MKKALQVVMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKTIDLESKKITIHHDPIAAVNWPEMTMRFTITPQTK
MSEIKTGDKVAFNFVQQGNLSLLQDIKVSQ

Specific function: Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide [H]

COG id: COG5569

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786786, Length=110, Percent_Identity=98.1818181818182, Blast_Score=221, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021647 [H]

Pfam domain/function: PF11604 CusF_Ec [H]

EC number: NA

Molecular weight: Translated: 12323; Mature: 12323

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKALQVVMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKTIDLESKKITIHHDP
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEECCCEEEEEECCCCEEEEECCC
IAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSLLQDIKVSQ
EEEECCCCEEEEEEECCCCHHHHCCCCCCEEEEECCCCCHHEECCCCCCC
>Mature Secondary Structure
MKKALQVVMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKTIDLESKKITIHHDP
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEECCCEEEEEECCCCEEEEECCC
IAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSLLQDIKVSQ
EEEECCCCEEEEEEECCCCHHHHCCCCCCEEEEECCCCCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]