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The map label for this gene is entC [H]

Identifier: 218549819

GI number: 218549819

Start: 2563305

End: 2564480

Strand: Reverse

Name: entC [H]

Synonym: EFER_2501

Alternate gene names: 218549819

Gene position: 2564480-2563305 (Counterclockwise)

Preceding gene: 218549821

Following gene: 218549818

Centisome position: 55.89

GC content: 56.04

Gene sequence:

>1176_bases
ATGGATACGTCACTGGCTGAGGAAGTACAGCAGACCATGGCAACACTTGCGCCCAATCGCTTTTTCTTTATGTCGCCGTA
CCGCAGTTTTACGACGTCAGGATGTTTCGCCCGCTTTGATGAACCGGCTGTGAACGGGGATTCGCCCGACAGTCCCTTCC
AGCAAAAACTCACCGCGCTGTTTGCCGATGCCAAAGCGCAGGGCATTAAAAATCCGGTGATGGTTGGGGCGATTCCCTTC
GATCCACGTCAGCCTTCGTCGCTGTATATTCCCGAATCCTGGCAGTCGTTCTCCCGGCTGGAAAAACAGACTTCAGCCCG
CCGTTTCACCCGCAGCCAGTCGCTGAACGTGGTGGAACGTCAGGCAATTCCTGAACAAGCTACGTTTGAACAGATGGTTG
CCCGCGCCGCCGCACTTACCGCCACGCCGCAAGTCGACAAAGTGGTGTTGTCACGGTTGATTGATATCACCACTGACGCC
GTCATTGATAGTGGCGTATTGCTGGAACGGTTGATTGTGCAAAACCCGGTTAGTTACAACTTCCATGTGCCGTTAGCTGA
TGGTGGCGTCCTGCTGGGAGCCAGCCCGGAACTGCTGCTACGTAAAGACGGCGAGCGTTTTAGCTCCATTCCGTTAGCCG
GTTCCGCGCGCCGTCAGCCGGATGACGTGCTCGATCGCGAAGCGGGTAATCGTCTGCTGGCGTCAGAAAAAGATCGCCAT
GAACATGAACTTGTCACTCAGGCGATGAAAGAGGTACTGCGCGAACGCAGTAGTGAGTTACACGTTCCATCCTCCCCACA
ATTGCTCACCACACCGACGCTGTGGCATCTCGCAACACCCTTTGAAGGCAAAGCGAATTCGCAAGAAAACGCATTGACTC
TGGCCTGTCTGCTGCATCCGACCCCCGCGCTGAGCGGTTTCCCGCATCAGGCCGCGACCCAGGTGATTGCTGAGCTGGAA
CCGTTCGACCGCGAACTGTTTGGCGGCATTGTGGGTTGGTGTGACAGCGAAGGTAACGGCGAGTGGGTGGTGACCATCCG
CTGCGCGAAGCTGCGGGAAAATCAGGTACGTCTGTTTGCCGGAGCGGGGATTGTGCCTGCGTCCTCACCGTTGGGTGAAT
GGCGCGAAACGGGCGTCAAACTTTCTACCATGTTGAACGTTTTTGGATTGCATTAA

Upstream 100 bases:

>100_bases
ACCTCAAGAGTTGACATAGTGCGCGTTTGCTTTTAGGTTAGCGACCGAAAATATAAATGATAATCATTATTAAAGCCTTT
ATCATTTTGTGGAGGATGAT

Downstream 100 bases:

>100_bases
GGAGCGAGGATGAGCATTCCATTCACCCGCTGGCCGGAAGAGTTTGCCCGTCGCTATCGGGAAAAAGGCTACTGGCAGGA
TTTGCCACTGACCGACATTC

Product: isochorismate synthase 1

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLTALFADAKAQGIKNPVMVGAIPF
DPRQPSSLYIPESWQSFSRLEKQTSARRFTRSQSLNVVERQAIPEQATFEQMVARAAALTATPQVDKVVLSRLIDITTDA
VIDSGVLLERLIVQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDDVLDREAGNRLLASEKDRH
EHELVTQAMKEVLRERSSELHVPSSPQLLTTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELE
PFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH

Sequences:

>Translated_391_residues
MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLTALFADAKAQGIKNPVMVGAIPF
DPRQPSSLYIPESWQSFSRLEKQTSARRFTRSQSLNVVERQAIPEQATFEQMVARAAALTATPQVDKVVLSRLIDITTDA
VIDSGVLLERLIVQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDDVLDREAGNRLLASEKDRH
EHELVTQAMKEVLRERSSELHVPSSPQLLTTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELE
PFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH
>Mature_391_residues
MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLTALFADAKAQGIKNPVMVGAIPF
DPRQPSSLYIPESWQSFSRLEKQTSARRFTRSQSLNVVERQAIPEQATFEQMVARAAALTATPQVDKVVLSRLIDITTDA
VIDSGVLLERLIVQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDDVLDREAGNRLLASEKDRH
EHELVTQAMKEVLRERSSELHVPSSPQLLTTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELE
PFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=391, Percent_Identity=97.9539641943734, Blast_Score=788, Evalue=0.0,
Organism=Escherichia coli, GI87082077, Length=276, Percent_Identity=31.8840579710145, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788114, Length=200, Percent_Identity=28, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787518, Length=223, Percent_Identity=30.0448430493274, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=212, Percent_Identity=28.7735849056604, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 42989; Mature: 42989

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLTAL
CCCHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCHHCCCCCCCCCCCCCCHHHHHHHHH
FADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRLEKQTSARRFTRSQSLNVVER
HHHHHHHCCCCCEEEEEECCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QAIPEQATFEQMVARAAALTATPQVDKVVLSRLIDITTDAVIDSGVLLERLIVQNPVSYN
HCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEE
FHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDDVLDREAGNRLLASEKDRH
EEEEECCCCEEECCCCCEEEECCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHH
EHELVTQAMKEVLRERSSELHVPSSPQLLTTPTLWHLATPFEGKANSQENALTLACLLHP
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHEECCCCCCCCCCCCCEEEEEEEECC
TPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFA
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCEEEEE
GAGIVPASSPLGEWRETGVKLSTMLNVFGLH
CCCCCCCCCCHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLTAL
CCCHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCHHCCCCCCCCCCCCCCHHHHHHHHH
FADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRLEKQTSARRFTRSQSLNVVER
HHHHHHHCCCCCEEEEEECCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QAIPEQATFEQMVARAAALTATPQVDKVVLSRLIDITTDAVIDSGVLLERLIVQNPVSYN
HCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEE
FHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDDVLDREAGNRLLASEKDRH
EEEEECCCCEEECCCCCEEEECCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHH
EHELVTQAMKEVLRERSSELHVPSSPQLLTTPTLWHLATPFEGKANSQENALTLACLLHP
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHEECCCCCCCCCCCCCEEEEEEEECC
TPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFA
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCEEEEE
GAGIVPASSPLGEWRETGVKLSTMLNVFGLH
CCCCCCCCCCHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]