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The map label for this gene is mutE [H]

Identifier: 218549700

GI number: 218549700

Start: 2434925

End: 2436370

Strand: Direct

Name: mutE [H]

Synonym: EFER_2377

Alternate gene names: 218549700

Gene position: 2434925-2436370 (Clockwise)

Preceding gene: 218549699

Following gene: 218549701

Centisome position: 53.06

GC content: 48.55

Gene sequence:

>1446_bases
ATGGAACTTAAAAATAAAAAACTCTCACTTGATGAATTCATGAACGAGCGACTGCAGGTACTCCAAACCTGGCCGACGGG
TAAGGAGGTAGAAAACTTTGCAGAGGCAGTTAACTATCAGCAATCAATTCCTGAACATAAACGCTTTTCTCTGGCCCTGT
TAAAAGCCGACCAGCAAGGTAAAACGTTGAGTCAACCACGTGCAGGCGTTGCATTGATCGATGAACATATAGAACTGCTG
AAAACGCTGGAACAGGAGTGTGATCTGCTGCCGACAACTATTGATGCTTATACCCGTTTGAATCGTTATGAGGAAGCAGC
TGTTGGTATTCAAAAATCGCTGGAAGCTGGCACCTCTAAACTGAATGGATTACCTGTTGTTAACCACGGTGTTGCAGCCT
GCCGTCGCCTGACAGAAACACTCGAAAAACCGTTACAAATTCGCCACGGTACGCCTGATGCCCGATTGCTGGCTGAAATT
TCCTTTGCCAGCGGTTTTACCAGCTACGAAGGCGGGGGAATTTCGTACAACATTCCTTATGCCAAACGTGTAACGCTGGA
AAAATCGATCCGCGACTGGCAATACTGCGACCGTCTGGTCGGGCTATATGAAGAACATGGTATTCGCATGAATCGGGAGC
CTTTTGGACCATTAACCGGCACCTTGATTCCTCCTTTTATGTCCCATTCGGTGGCGATTATTGAAGGTCTTTTGGCACTG
GAACAGGGAGTGAAATCAATTACTGTCGGTTATGGTCAGGTGGGCAGCCTGATACAGGATATTGCAGCCATTAAATCCCT
GCGCGAACTGTCCCATGAATATTTCCATAATTACGGGTATGAGGATTACGAACTGAGTACGGTTTTCCACCAATGGATGG
GGGGATTCCCGGAAGATGAAGCTAAAGCCTTTGCCATAATTTCCTGGGGAGCTGCTGTTGCTGGCATGTCAGGTGCGACA
AAAGTGATTACCAAAAGCCCCCATGAAGCATTTGGTATCCCAACTGCTGCAGCCAATGCTCAGGGGCTGAAAGCCTCGCG
CCAGATGTTAAATATGGTAAGCGAACAGAAATTCCCCCCCTGTCCGGCGGTTGATCAAGAGGTTGAACTGATCAAGTGCG
AAGTTCGCGCTGTACTGAAAAAAGTGTTTGAACTGGGTAATGGCGATATTGCCCGTGGCACAGTGTTGGCCTTTGAAGCG
GGTGTGCTGGATATCCCCTTTGCCCCATCAGTTTGTAATGCCGGGAAGATCTTGCCTGTACGCGATAACACCGGGGCAAT
TCGTCTTCTTGAAGCCGGTTGCGTACCGTTACCGCAAGATATCCTCGCCCTGCATCACGACTACGTAGCAGAACGCGCCC
GTGCAGAAGGACGCGGCCCATCATTCCAGATGGTTATTGATGACATTAACGCCGTATCCCACAGTCAATTAATAGGAAGA
CCATAA

Upstream 100 bases:

>100_bases
CTTGCTGCCGTTACTGGCAAATGTTGCCCGACTTGATCCGCAGCTCGCCGCCCGTACCAGTATCCACTGTTTAACCCGAT
GAATTAAAAGGCAGCAACAC

Downstream 100 bases:

>100_bases
ATGAAAATTAAACAGGCCATCTTCACCGCCGGGTACTCTTCATTCTATTTTGACGATCAGCAAGCCATTAAAAATGGCGC
AGGACACGATGGGTTTATTT

Product: methylaspartate mutase E chain

Products: NA

Alternate protein names: Glutamate mutase subunit epsilon [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MELKNKKLSLDEFMNERLQVLQTWPTGKEVENFAEAVNYQQSIPEHKRFSLALLKADQQGKTLSQPRAGVALIDEHIELL
KTLEQECDLLPTTIDAYTRLNRYEEAAVGIQKSLEAGTSKLNGLPVVNHGVAACRRLTETLEKPLQIRHGTPDARLLAEI
SFASGFTSYEGGGISYNIPYAKRVTLEKSIRDWQYCDRLVGLYEEHGIRMNREPFGPLTGTLIPPFMSHSVAIIEGLLAL
EQGVKSITVGYGQVGSLIQDIAAIKSLRELSHEYFHNYGYEDYELSTVFHQWMGGFPEDEAKAFAIISWGAAVAGMSGAT
KVITKSPHEAFGIPTAAANAQGLKASRQMLNMVSEQKFPPCPAVDQEVELIKCEVRAVLKKVFELGNGDIARGTVLAFEA
GVLDIPFAPSVCNAGKILPVRDNTGAIRLLEAGCVPLPQDILALHHDYVAERARAEGRGPSFQMVIDDINAVSHSQLIGR
P

Sequences:

>Translated_481_residues
MELKNKKLSLDEFMNERLQVLQTWPTGKEVENFAEAVNYQQSIPEHKRFSLALLKADQQGKTLSQPRAGVALIDEHIELL
KTLEQECDLLPTTIDAYTRLNRYEEAAVGIQKSLEAGTSKLNGLPVVNHGVAACRRLTETLEKPLQIRHGTPDARLLAEI
SFASGFTSYEGGGISYNIPYAKRVTLEKSIRDWQYCDRLVGLYEEHGIRMNREPFGPLTGTLIPPFMSHSVAIIEGLLAL
EQGVKSITVGYGQVGSLIQDIAAIKSLRELSHEYFHNYGYEDYELSTVFHQWMGGFPEDEAKAFAIISWGAAVAGMSGAT
KVITKSPHEAFGIPTAAANAQGLKASRQMLNMVSEQKFPPCPAVDQEVELIKCEVRAVLKKVFELGNGDIARGTVLAFEA
GVLDIPFAPSVCNAGKILPVRDNTGAIRLLEAGCVPLPQDILALHHDYVAERARAEGRGPSFQMVIDDINAVSHSQLIGR
P
>Mature_481_residues
MELKNKKLSLDEFMNERLQVLQTWPTGKEVENFAEAVNYQQSIPEHKRFSLALLKADQQGKTLSQPRAGVALIDEHIELL
KTLEQECDLLPTTIDAYTRLNRYEEAAVGIQKSLEAGTSKLNGLPVVNHGVAACRRLTETLEKPLQIRHGTPDARLLAEI
SFASGFTSYEGGGISYNIPYAKRVTLEKSIRDWQYCDRLVGLYEEHGIRMNREPFGPLTGTLIPPFMSHSVAIIEGLLAL
EQGVKSITVGYGQVGSLIQDIAAIKSLRELSHEYFHNYGYEDYELSTVFHQWMGGFPEDEAKAFAIISWGAAVAGMSGAT
KVITKSPHEAFGIPTAAANAQGLKASRQMLNMVSEQKFPPCPAVDQEVELIKCEVRAVLKKVFELGNGDIARGTVLAFEA
GVLDIPFAPSVCNAGKILPVRDNTGAIRLLEAGCVPLPQDILALHHDYVAERARAEGRGPSFQMVIDDINAVSHSQLIGR
P

Specific function: Unknown

COG id: COG4865

COG function: function code E; Glutamate mutase epsilon subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016176
- InterPro:   IPR014348
- InterPro:   IPR006396
- InterPro:   IPR014714 [H]

Pfam domain/function: PF06368 Met_asp_mut_E [H]

EC number: =5.4.99.1 [H]

Molecular weight: Translated: 52864; Mature: 52864

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKNKKLSLDEFMNERLQVLQTWPTGKEVENFAEAVNYQQSIPEHKRFSLALLKADQQG
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHEEEEEECCCCC
KTLSQPRAGVALIDEHIELLKTLEQECDLLPTTIDAYTRLNRYEEAAVGIQKSLEAGTSK
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNGLPVVNHGVAACRRLTETLEKPLQIRHGTPDARLLAEISFASGFTSYEGGGISYNIPY
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCC
AKRVTLEKSIRDWQYCDRLVGLYEEHGIRMNREPFGPLTGTLIPPFMSHSVAIIEGLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EQGVKSITVGYGQVGSLIQDIAAIKSLRELSHEYFHNYGYEDYELSTVFHQWMGGFPEDE
HHCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
AKAFAIISWGAAVAGMSGATKVITKSPHEAFGIPTAAANAQGLKASRQMLNMVSEQKFPP
CCEEEEEEHHHHHHCCCCCCHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
CPAVDQEVELIKCEVRAVLKKVFELGNGDIARGTVLAFEAGVLDIPFAPSVCNAGKILPV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEECCCCCCCCCCCCEEEE
RDNTGAIRLLEAGCVPLPQDILALHHDYVAERARAEGRGPSFQMVIDDINAVSHSQLIGR
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCC
P
C
>Mature Secondary Structure
MELKNKKLSLDEFMNERLQVLQTWPTGKEVENFAEAVNYQQSIPEHKRFSLALLKADQQG
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHEEEEEECCCCC
KTLSQPRAGVALIDEHIELLKTLEQECDLLPTTIDAYTRLNRYEEAAVGIQKSLEAGTSK
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNGLPVVNHGVAACRRLTETLEKPLQIRHGTPDARLLAEISFASGFTSYEGGGISYNIPY
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCC
AKRVTLEKSIRDWQYCDRLVGLYEEHGIRMNREPFGPLTGTLIPPFMSHSVAIIEGLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EQGVKSITVGYGQVGSLIQDIAAIKSLRELSHEYFHNYGYEDYELSTVFHQWMGGFPEDE
HHCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
AKAFAIISWGAAVAGMSGATKVITKSPHEAFGIPTAAANAQGLKASRQMLNMVSEQKFPP
CCEEEEEEHHHHHHCCCCCCHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
CPAVDQEVELIKCEVRAVLKKVFELGNGDIARGTVLAFEAGVLDIPFAPSVCNAGKILPV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEECCCCCCCCCCCCEEEE
RDNTGAIRLLEAGCVPLPQDILALHHDYVAERARAEGRGPSFQMVIDDINAVSHSQLIGR
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8428631; 8454064; 1420191; 1397267 [H]