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The map label for this gene is mngB [H]

Identifier: 218549695

GI number: 218549695

Start: 2427185

End: 2429818

Strand: Reverse

Name: mngB [H]

Synonym: EFER_2372

Alternate gene names: 218549695

Gene position: 2429818-2427185 (Counterclockwise)

Preceding gene: 218549696

Following gene: 218549694

Centisome position: 52.95

GC content: 49.09

Gene sequence:

>2634_bases
ATGAAAGCTGTATCTCGCGTTCACATCACCCCGCATATGCACTGGGATCGGGAGTGGTATTTTACTACCGAAGAGTCACG
CATTCTGCTGGTCAATAATATGGAAGAGATCCTGTGCCGACTGGAACAGGACAACGAATACAAATATTACGTGCTCGACG
GGCAAACGGCGATTCTCGAAGATTATTTCGCGGTGAAGCCGGAAAACAAAGACCGCGTGAAAAAACTGGTAGAAGCCGGT
AAGTTGATTATCGGCCCCTGGTATACCCAGACCGATACCACGATTGTTTCTGCGGAATCCATAGTCCGTAATCTGATGTA
CGGAATGCGTGACTGCCTCGCGTTTGGCGAGCCGATGAAAATAGGCTATTTACCGGACTCCTTTGGCATGTCCGGGCAAC
TGCCGCATATCTACAATGGATTTGGCATTACCCGCACTATGTTCTGGCGCGGATGTTCGGAGCGCCACGGTACTGATAAA
ACCGAGTTTTTATGGAAAAGCAGTGACGGCAGCGAAGTGACGGCGCAAGTGCTGCCGTTAGGTTATGCCATCGGTAAGTA
CTTACCTGCGGACGAAGACGGATTACGTAAACGGCTCGACAGCTATTTTGACGTGCTGGAAAAAGCGTCAGTAACCAAAG
AGATTTTGTTGCCGAATGGTCATGATCAGATGCCATTGCAGCAAAATATCTTCGAAGTGATGGATAAGCTGCGTGAGATC
TACCCTCAACGTAAGTTTGTGATGAGCCGCTTTGAAGAGGTATTTGAGAAGATAGAAGCGCAGCGCGAAAATTTGGCCAC
CCTGAAAGGGGAATTTATTGATGGCAAATATATGCGCGTGCATCGCACCATCGGTTCTACGCGTATGGATATCAAAATTG
CCCACGCACGTATTGAAAATAAGATTGTTAATCTGCTGGAACCGCTGGCAACACTGGCCTGGACGTTGGGTTTTGAATAC
CACCACGGCTTGCTGGAGAAAATGTGGAAAGAGATCTTAAAAAATCATGCCCACGACAGTATCGGTTGTTGTTGCAGTGA
CAAAGTTCATCGCGAAATCGTCGCCCGCTTCGAACTGGCCGAAGACATGGCGGATAATCTGATTCGTTTCTATATGCGTA
AAATCGCCGACAACATGCCGCAGAGCGACGCCGACAAACTCGTCCTGTTTAACCTGATGCCCTGGCCGCGTGAAGAAGTT
ATTAACACCACTGTGCGCCTGCGCGCCAGCCAGTTTAATTTGCGGGACGATCGCGGCCAGCCTGTGCCGTATTTTATTCG
CCATGCCCGTGAGATCGATCCTGGTCTTATCGATCGGCAAATTGTTCATTACGGTAATTACGATCCCTTTATGGAGTTTG
ATATTCAGATCAACCAGATTGTCCCTTCTATGGGCTATCGCACGCTTTATATTGAAGCGAATCAGCCTGGCAACGTGGTC
ACCTCCAAAAGTGAAGTTGAAGGGATACTGGAAAATGCTTTCTGGCAGATTGCGCTCAATGAGGATGGTTCTCTGCAACT
GGTAGATAAAGACAGCGGTGTGCGCTTTGAACGGGTGTTGCAAATTGAAGAAAGCTCTGATGATGGTGATGAATATGACT
ATTCACCTGCAAAAGAAGAGTGGGTAATTACTTCGGCGAACGCGAAACCGCAATGCGAGATTACTCATGAGGCCTGGCAG
AGTACGGCTGTTATCCGCTATGACATGGCAGTTCCGCTCAATTTGTCAGAACGCAGCGCCCGGCAATCCACTGGCAGAGT
AGGGGTGGAGTTGGTTGTCACTCTTAGTCATAACAGCAGGCGCATTGATGTGGATATCAACCTTGATAACCAGGCTGACG
ATCATCGCCTTCGCATACTGGTCCCTACACCTTTTAACACCGACAGTGTTCTGGCTGACACCCAGTTTGGTTCACTAACG
CGCCCGGTGAGCGACAGTGCGATGGATGTCTGGCAACAAGAAGGCTGGAAAGAAGCGCCTGTTCCGGTATGGAATATGCT
CAGTTATGCAGCCTTACAAGAGGAACGTAACGGGCTGGCTGTTTTTAGCGAAGGGCTGCGTGAGTTTGAGGTTATTGGTG
AAAAGAATAAATCTTTTGCCATTACGCTGCTGCGTGGAGTTGGATTGCTGGGGAAAGAAGATCTGCTTTTAAGGCCTGGA
CGGCCTTCAGGAATTAAAATGCCAGTCCCAGACTCACAACTACGCGGTCTGCTTTCTTGTCGCCTAAGTTTATTGAGTTA
TACCGGTACGCCAACCGCCGCCGGTGTAGCCCAGCAGGCGCGAGCATGGCTGACCCCAGTACAGTGTTACAACAAAATCC
CATGGGATGCGATGAAGCTTAACAAAGCCGGGTTCAACGTGCCGGAAAGTTATAGTTTGTTGAAAATGCCCCCAGTGGGA
TGCCTGATTAGCGCACTTAAGAAAGCTGAAGACCGACAAGAAGTGATTTTGCGGCTGTTTAATCCGGCTGAATCAGCGAC
CTGTGATGCGACTGTTGCTTTCAGCCGCGAGGTGATTTCTTGCTCAGAAACGATGATGGATGAACACATTACTACCGAGG
AAAATCAAGGTTCAAATCTGTCCGGGCCTTTTTTACCCGGCCAGTCACGAACGTTCAGTTACCGACTTGCCTGA

Upstream 100 bases:

>100_bases
ATCTCTACCGCAATTCTCCTGATCTGGCGGCGTCACGCGGTTAAGCATGGCAACTATCTGATTGACGGCGTAACGCCATA
AACAAAAACAGGAAACGACG

Downstream 100 bases:

>100_bases
ATAGCGAGTAACCAAAGCGAAGCCACGTATGCGCGGCCAGATTGTTGACAAAGGGCGCTTTGTTCATGCCGGATGCGGCA
TGAACGCCTTATTCGGTCTG

Product: alpha-mannosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 877; Mature: 877

Protein sequence:

>877_residues
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILEDYFAVKPENKDRVKKLVEAG
KLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
TEFLWKSSDGSEVTAQVLPLGYAIGKYLPADEDGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMDKLREI
YPQRKFVMSRFEEVFEKIEAQRENLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEY
HHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNLMPWPREEV
INTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVV
TSKSEVEGILENAFWQIALNEDGSLQLVDKDSGVRFERVLQIEESSDDGDEYDYSPAKEEWVITSANAKPQCEITHEAWQ
STAVIRYDMAVPLNLSERSARQSTGRVGVELVVTLSHNSRRIDVDINLDNQADDHRLRILVPTPFNTDSVLADTQFGSLT
RPVSDSAMDVWQQEGWKEAPVPVWNMLSYAALQEERNGLAVFSEGLREFEVIGEKNKSFAITLLRGVGLLGKEDLLLRPG
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKLNKAGFNVPESYSLLKMPPVG
CLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA

Sequences:

>Translated_877_residues
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILEDYFAVKPENKDRVKKLVEAG
KLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
TEFLWKSSDGSEVTAQVLPLGYAIGKYLPADEDGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMDKLREI
YPQRKFVMSRFEEVFEKIEAQRENLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEY
HHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNLMPWPREEV
INTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVV
TSKSEVEGILENAFWQIALNEDGSLQLVDKDSGVRFERVLQIEESSDDGDEYDYSPAKEEWVITSANAKPQCEITHEAWQ
STAVIRYDMAVPLNLSERSARQSTGRVGVELVVTLSHNSRRIDVDINLDNQADDHRLRILVPTPFNTDSVLADTQFGSLT
RPVSDSAMDVWQQEGWKEAPVPVWNMLSYAALQEERNGLAVFSEGLREFEVIGEKNKSFAITLLRGVGLLGKEDLLLRPG
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKLNKAGFNVPESYSLLKMPPVG
CLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA
>Mature_877_residues
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILEDYFAVKPENKDRVKKLVEAG
KLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
TEFLWKSSDGSEVTAQVLPLGYAIGKYLPADEDGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMDKLREI
YPQRKFVMSRFEEVFEKIEAQRENLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEY
HHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNLMPWPREEV
INTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVV
TSKSEVEGILENAFWQIALNEDGSLQLVDKDSGVRFERVLQIEESSDDGDEYDYSPAKEEWVITSANAKPQCEITHEAWQ
STAVIRYDMAVPLNLSERSARQSTGRVGVELVVTLSHNSRRIDVDINLDNQADDHRLRILVPTPFNTDSVLADTQFGSLT
RPVSDSAMDVWQQEGWKEAPVPVWNMLSYAALQEERNGLAVFSEGLREFEVIGEKNKSFAITLLRGVGLLGKEDLLLRPG
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKLNKAGFNVPESYSLLKMPPVG
CLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA

Specific function: May hydrolyze mannosyl-D-glycerate to mannose-6- phosphate and glycerate [H]

COG id: COG0383

COG function: function code G; Alpha-mannosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 38 family [H]

Homologues:

Organism=Homo sapiens, GI46852164, Length=410, Percent_Identity=23.9024390243902, Blast_Score=86, Evalue=2e-16,
Organism=Escherichia coli, GI1786952, Length=877, Percent_Identity=96.8072976054732, Blast_Score=1761, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321282, Length=443, Percent_Identity=23.9277652370203, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR011330
- InterPro:   IPR011682
- InterPro:   IPR015341
- InterPro:   IPR000602 [H]

Pfam domain/function: PF09261 Alpha-mann_mid; PF01074 Glyco_hydro_38; PF07748 Glyco_hydro_38C [H]

EC number: NA

Molecular weight: Translated: 99996; Mature: 99996

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILE
CCCCCEEEECCCCCCCCEEEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCHHHH
DYFAVKPENKDRVKKLVEAGKLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMK
HHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCE
IGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDKTEFLWKSSDGSEVTAQVLPL
EECCCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCCCHHEEEECCCCCEEEHHHHHH
GYAIGKYLPADEDGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMDKLREI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
YPQRKFVMSRFEEVFEKIEAQRENLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCEEEEEEHHHHHHH
KIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EDMADNLIRFYMRKIADNMPQSDADKLVLFNLMPWPREEVINTTVRLRASQFNLRDDRGQ
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHCHHHEEEEHHCCCCCCCCC
PVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVV
CCHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEEEEEEHHCCCCCCEEEEEEECCCCCEE
TSKSEVEGILENAFWQIALNEDGSLQLVDKDSGVRFERVLQIEESSDDGDEYDYSPAKEE
ECHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCC
WVITSANAKPQCEITHEAWQSTAVIRYDMAVPLNLSERSARQSTGRVGVELVVTLSHNSR
EEEEECCCCCCEEEEHHHHCCCEEEEEEEEECCCCCHHHHHHHCCCCEEEEEEEEECCCE
RIDVDINLDNQADDHRLRILVPTPFNTDSVLADTQFGSLTRPVSDSAMDVWQQEGWKEAP
EEEEEEECCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCC
VPVWNMLSYAALQEERNGLAVFSEGLREFEVIGEKNKSFAITLLRGVGLLGKEDLLLRPG
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCEEECCC
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHEE
NKAGFNVPESYSLLKMPPVGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVIS
CCCCCCCCCCCCEEECCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHH
CSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILE
CCCCCEEEECCCCCCCCEEEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCHHHH
DYFAVKPENKDRVKKLVEAGKLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMK
HHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCE
IGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDKTEFLWKSSDGSEVTAQVLPL
EECCCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCCCHHEEEECCCCCEEEHHHHHH
GYAIGKYLPADEDGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMDKLREI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
YPQRKFVMSRFEEVFEKIEAQRENLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCEEEEEEHHHHHHH
KIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EDMADNLIRFYMRKIADNMPQSDADKLVLFNLMPWPREEVINTTVRLRASQFNLRDDRGQ
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHCHHHEEEEHHCCCCCCCCC
PVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVV
CCHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEEEEEEHHCCCCCCEEEEEEECCCCCEE
TSKSEVEGILENAFWQIALNEDGSLQLVDKDSGVRFERVLQIEESSDDGDEYDYSPAKEE
ECHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCC
WVITSANAKPQCEITHEAWQSTAVIRYDMAVPLNLSERSARQSTGRVGVELVVTLSHNSR
EEEEECCCCCCEEEEHHHHCCCEEEEEEEEECCCCCHHHHHHHCCCCEEEEEEEEECCCE
RIDVDINLDNQADDHRLRILVPTPFNTDSVLADTQFGSLTRPVSDSAMDVWQQEGWKEAP
EEEEEEECCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCC
VPVWNMLSYAALQEERNGLAVFSEGLREFEVIGEKNKSFAITLLRGVGLLGKEDLLLRPG
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCEEECCC
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHEE
NKAGFNVPESYSLLKMPPVGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVIS
CCCCCCCCCCCCEEECCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHH
CSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9063979 [H]