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The map label for this gene is yeiQ [H]

Identifier: 218549588

GI number: 218549588

Start: 2320154

End: 2321629

Strand: Direct

Name: yeiQ [H]

Synonym: EFER_2261

Alternate gene names: 218549588

Gene position: 2320154-2321629 (Clockwise)

Preceding gene: 218549586

Following gene: 218549589

Centisome position: 50.56

GC content: 48.37

Gene sequence:

>1476_bases
GTGCCATCAATGAAAACCATCGCCTCAGCCCAACTTCCCCAGGGAGTGCTGACACCACATTATGATCGGCAAAAGCTACA
ATCCCGTATTGTTCATTTTGGCTTTGGTGCGTTTCATCGGGCACATCAGGCTTTATTAACTGACCGGGTACTTAATGCCC
GTGGTGGTGACTGGGGGATCTGCGAAATCAGCCTGTTTAGCGGCGATCATTTAATGCGTCAACTCCGTGAGCAGGATCAT
CTATTTACTGTTCTTGAGAAAGGCGCTGAGGGCGATCAGGCCATTATTATTGGCGCTGTTCATGAATGTCTTAATGCGAA
ACTGGATTCATTAGCCGCCATTATTGAGAAATTCTGCGAACCGCAGGTGGCGATTGTTTCACTGACCATTACAGAAAAAG
GCTATTGCATCGACCCGTCTACGGGTGAACTTGATCTGCATAACGCAAGAATCCTTCATGACCTTGCATCTCCGCAAGAA
CCCCATTCAGCACCAGGCATTCTGGTTGAAGCGCTGGCTCGTCGTCACCAGCGTGGCTTGCCACCCTTTACCGTGCTCTC
TTGCGACAATATTCCTGACAATGGTCATGTTGTAAAAAATGCCGTGTTGGGAATGGCCGCAAGACGTTCACCAGAACTGG
CAGAATGGATAAAAACACATGTCAGCTTCCCTGCCACAATGGTTGATCGCATTGTTCCTGCGGCAACAGAAGAGTCTCTG
GCTGAAATATCTCAGCATCTGGGCGTTACTGATCCTTGTGCAATAAGTTGTGAGCCGTTTATTCAGTGGGTCGTGGAGGA
TGATTTTGTTGCCGGAAGACCTGAATGGGAAGTCGCAGGTGTACAAATGGTCCGTGATGTCGTGCCATGGGAAGAGATGA
AATTGCGGATGCTTAATGGCAGCCACTCATTTCTCGCTTATCTTGGCTATCTCTCAGGTTTTGCACATATCAACGACTGT
ATGCAAGACAAGGTATTTCGCCAGGCTGCACGACGTTTAATGCTGCAGGAGCAAGCCCCCACGTTGCAAATTACGGACGT
TGATCTCACGCTTTATGCCGACAAACTTATCGAACGCTTCGCTAACCCGGCTTTGAAGCATAAAACCTGGCAGATCGCGA
TGGATGGCAGTCAGAAATTGCCTCAAAGAATGCTCGCCAGTATTCGTATTCATTTGCAACGTGAAAGTACCTGGCCTCTG
CTGGCGCTAGGTGTTGCAGGCTGGATGCGTTACGTCAGTGGCTTTGACGATGCAAACAAAACCATAGATGTCCGTGATCC
ACTTGGTGACAAAATCGCCATACTCGTGGCAAAAAGTACATCAGCGCAGCGAGTAAAAACCTTGTTATCACTCAATGAAA
TATTCGGTGAGGACCTGCCAGACAATCCTCGATTTGTTGAGGCGATTAGCGAAGCATGGCAGCAAATCGAGCAATATGGC
GCTCATCAAGCCGTCGCTCATGCACTAAAAAATTAA

Upstream 100 bases:

>100_bases
TGATCTCCTTCACACTTCAGATTATTAACAAATCACACCAATATTATTTTCTGTCATATAACTTTAAAGTAACAATATTT
AGTACAAACATTCTTAAGGT

Downstream 100 bases:

>100_bases
CAATTTCTGCGGTATAAGCGGGTGATCCCTCTGGTTACCCGCTCAGTTCTTCTCTTTTTGCTCTTTTTTGTCCAGGATTA
ATAGCAAATTTCGTTTCTCA

Product: sugar dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MPSMKTIASAQLPQGVLTPHYDRQKLQSRIVHFGFGAFHRAHQALLTDRVLNARGGDWGICEISLFSGDHLMRQLREQDH
LFTVLEKGAEGDQAIIIGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPSTGELDLHNARILHDLASPQE
PHSAPGILVEALARRHQRGLPPFTVLSCDNIPDNGHVVKNAVLGMAARRSPELAEWIKTHVSFPATMVDRIVPAATEESL
AEISQHLGVTDPCAISCEPFIQWVVEDDFVAGRPEWEVAGVQMVRDVVPWEEMKLRMLNGSHSFLAYLGYLSGFAHINDC
MQDKVFRQAARRLMLQEQAPTLQITDVDLTLYADKLIERFANPALKHKTWQIAMDGSQKLPQRMLASIRIHLQRESTWPL
LALGVAGWMRYVSGFDDANKTIDVRDPLGDKIAILVAKSTSAQRVKTLLSLNEIFGEDLPDNPRFVEAISEAWQQIEQYG
AHQAVAHALKN

Sequences:

>Translated_491_residues
MPSMKTIASAQLPQGVLTPHYDRQKLQSRIVHFGFGAFHRAHQALLTDRVLNARGGDWGICEISLFSGDHLMRQLREQDH
LFTVLEKGAEGDQAIIIGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPSTGELDLHNARILHDLASPQE
PHSAPGILVEALARRHQRGLPPFTVLSCDNIPDNGHVVKNAVLGMAARRSPELAEWIKTHVSFPATMVDRIVPAATEESL
AEISQHLGVTDPCAISCEPFIQWVVEDDFVAGRPEWEVAGVQMVRDVVPWEEMKLRMLNGSHSFLAYLGYLSGFAHINDC
MQDKVFRQAARRLMLQEQAPTLQITDVDLTLYADKLIERFANPALKHKTWQIAMDGSQKLPQRMLASIRIHLQRESTWPL
LALGVAGWMRYVSGFDDANKTIDVRDPLGDKIAILVAKSTSAQRVKTLLSLNEIFGEDLPDNPRFVEAISEAWQQIEQYG
AHQAVAHALKN
>Mature_490_residues
PSMKTIASAQLPQGVLTPHYDRQKLQSRIVHFGFGAFHRAHQALLTDRVLNARGGDWGICEISLFSGDHLMRQLREQDHL
FTVLEKGAEGDQAIIIGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPSTGELDLHNARILHDLASPQEP
HSAPGILVEALARRHQRGLPPFTVLSCDNIPDNGHVVKNAVLGMAARRSPELAEWIKTHVSFPATMVDRIVPAATEESLA
EISQHLGVTDPCAISCEPFIQWVVEDDFVAGRPEWEVAGVQMVRDVVPWEEMKLRMLNGSHSFLAYLGYLSGFAHINDCM
QDKVFRQAARRLMLQEQAPTLQITDVDLTLYADKLIERFANPALKHKTWQIAMDGSQKLPQRMLASIRIHLQRESTWPLL
ALGVAGWMRYVSGFDDANKTIDVRDPLGDKIAILVAKSTSAQRVKTLLSLNEIFGEDLPDNPRFVEAISEAWQQIEQYGA
HQAVAHALKN

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxuB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=487, Percent_Identity=82.7515400410678, Blast_Score=841, Evalue=0.0,
Organism=Escherichia coli, GI1790779, Length=486, Percent_Identity=55.761316872428, Blast_Score=552, Evalue=1e-158,
Organism=Escherichia coli, GI1787823, Length=469, Percent_Identity=54.5842217484009, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI48994885, Length=422, Percent_Identity=23.4597156398104, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790028, Length=257, Percent_Identity=26.4591439688716, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324401, Length=476, Percent_Identity=37.8151260504202, Blast_Score=350, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6320765, Length=476, Percent_Identity=37.8151260504202, Blast_Score=350, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 54675; Mature: 54544

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSMKTIASAQLPQGVLTPHYDRQKLQSRIVHFGFGAFHRAHQALLTDRVLNARGGDWGI
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
CEISLFSGDHLMRQLREQDHLFTVLEKGAEGDQAIIIGAVHECLNAKLDSLAAIIEKFCE
EEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
PQVAIVSLTITEKGYCIDPSTGELDLHNARILHDLASPQEPHSAPGILVEALARRHQRGL
CCEEEEEEEEECCCEEECCCCCCEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
PPFTVLSCDNIPDNGHVVKNAVLGMAARRSPELAEWIKTHVSFPATMVDRIVPAATEESL
CCEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHH
AEISQHLGVTDPCAISCEPFIQWVVEDDFVAGRPEWEVAGVQMVRDVVPWEEMKLRMLNG
HHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCC
SHSFLAYLGYLSGFAHINDCMQDKVFRQAARRLMLQEQAPTLQITDVDLTLYADKLIERF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
ANPALKHKTWQIAMDGSQKLPQRMLASIRIHLQRESTWPLLALGVAGWMRYVSGFDDANK
CCHHHHCCEEEEEECCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
TIDVRDPLGDKIAILVAKSTSAQRVKTLLSLNEIFGEDLPDNPRFVEAISEAWQQIEQYG
EEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC
AHQAVAHALKN
HHHHHHHHHCC
>Mature Secondary Structure 
PSMKTIASAQLPQGVLTPHYDRQKLQSRIVHFGFGAFHRAHQALLTDRVLNARGGDWGI
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
CEISLFSGDHLMRQLREQDHLFTVLEKGAEGDQAIIIGAVHECLNAKLDSLAAIIEKFCE
EEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
PQVAIVSLTITEKGYCIDPSTGELDLHNARILHDLASPQEPHSAPGILVEALARRHQRGL
CCEEEEEEEEECCCEEECCCCCCEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
PPFTVLSCDNIPDNGHVVKNAVLGMAARRSPELAEWIKTHVSFPATMVDRIVPAATEESL
CCEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHH
AEISQHLGVTDPCAISCEPFIQWVVEDDFVAGRPEWEVAGVQMVRDVVPWEEMKLRMLNG
HHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCC
SHSFLAYLGYLSGFAHINDCMQDKVFRQAARRLMLQEQAPTLQITDVDLTLYADKLIERF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
ANPALKHKTWQIAMDGSQKLPQRMLASIRIHLQRESTWPLLALGVAGWMRYVSGFDDANK
CCHHHHCCEEEEEECCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
TIDVRDPLGDKIAILVAKSTSAQRVKTLLSLNEIFGEDLPDNPRFVEAISEAWQQIEQYG
EEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC
AHQAVAHALKN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]