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The map label for this gene is yeiM [H]

Identifier: 218549578

GI number: 218549578

Start: 2308618

End: 2309868

Strand: Reverse

Name: yeiM [H]

Synonym: EFER_2250

Alternate gene names: 218549578

Gene position: 2309868-2308618 (Counterclockwise)

Preceding gene: 218549579

Following gene: 218549576

Centisome position: 50.34

GC content: 50.52

Gene sequence:

>1251_bases
ATGGATATAATGAGAAGTTTGGTGGGTATGGTGGTATTGCTGGCAATTGCATTCTTATTGTCAGTGAATAAAAAGCGTAT
CAGCGTACGCACGGTCGGAGCTGCATTGCTGCTGCAAATCGCTATTGGCGGAATCATGCTCTATTTTCCACCCGGAAAAT
GGGCGGTAGAGCAGGCGGCATTAGGCGTACATAAAGTGATGTCTTACAGTGACGCCGGAAGTGCCTTTATTTTTGGTTCG
TTGGTCGGGCCGAAAATGGATGTCCTGTTTGATGGCGCAGGCTTTATCTTCGCCTTTCGCGTACTTCCGGCGATTATTTT
TGTCACTGCGCTCATCAGCCTGCTGTACTACATTGGCGTGATGGGGCTGCTAATCCGCATTCTTGGCAGTATTTTTCAGA
AAGCCCTCAACATCAGCAAAATCGAATCTTTTGTTGCGGTTACCACTATTTTCCTTGGGCAAAATGAGATCCCGGCGATC
GTAAAACCGTTTATCGATCGCATGAATCGCAACGAGTTGTTTACCGCAATTTGCAGCGGGATGGCGTCCATTGCTGGTTC
GATGATGATTGGTTATGCCGGAATGGGCGTACCAATAGACTACCTGTTAGCGGCATCGCTGATGGCGATCCCCGGTGGTA
TTCTGTTTGCGCGTATTCTTAGCCCGGCAACCGAGCCTTCGCAGGTGACATTTGAAAATCTGTCGTTCAGCGAAACGCCG
CCAAAAAGTTTTATCGAAGCGGCGGCGAGCGGTGCGATGACCGGGTTGAAAATCGCCGCTGGTGTGGCGACGGTGGTAAT
GGCGTTTGTGGCAATTATTGCGCTGATCAACGGCATTATCGGCGGAATTGGTGGCTGGTTTGGTTTTTCCAATGCCTCTC
TGGAAAGTATTTTTGGCTATGTGCTGGCACCGCTGGCGTGGATCATGGGTGTGGACTGGAGTGATGCCAACCTTGCGGGT
AGCCTGATTGGGCAGAAACTGGCGATTAACGAATTCGTCGCTTACCTGAGTTTCTCTCCATACCTGCAAACGGGCGGCAC
GCTGGAAGTGAAAACCATTGCGATTATCTCCTTTGCGCTTTGTGGTTTTGCTAACTTTGGTTCTATCGGTGTAGTCGTTG
GGGCGTTTTCGGCTATTTCGCCAAAACGCGCGCCGGAAATCGCTCAGCTTGGGTTACGGGCGTTGGCAGCAGCAACGCTT
TCCAACCTGATGAGCGCGACCATTGCCGGGTTCTTTATTGGTTTAGCTTGA

Upstream 100 bases:

>100_bases
GGGTTAATTTCTGACGGGCAGAAAGCCGTCGCCCGTACTGATCATACATACCGAAACCTGGCGCTTGCGCCGGGTTTACT
GGCATGAAAGGAAAATCATT

Downstream 100 bases:

>100_bases
GTTTCATTACCGGATGTACGCGCTTATTAAGCGTTGCATCCGGCAATCGCGCTATTCCAGATTATTTTTTACTGCATCAT
CCCGGAGAATTTATTCTCCG

Product: sodium/proton nucleoside transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDIMRSLVGMVVLLAIAFLLSVNKKRISVRTVGAALLLQIAIGGIMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGS
LVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFSNASLESIFGYVLAPLAWIMGVDWSDANLAG
SLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATL
SNLMSATIAGFFIGLA

Sequences:

>Translated_416_residues
MDIMRSLVGMVVLLAIAFLLSVNKKRISVRTVGAALLLQIAIGGIMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGS
LVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFSNASLESIFGYVLAPLAWIMGVDWSDANLAG
SLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATL
SNLMSATIAGFFIGLA
>Mature_416_residues
MDIMRSLVGMVVLLAIAFLLSVNKKRISVRTVGAALLLQIAIGGIMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGS
LVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFSNASLESIFGYVLAPLAWIMGVDWSDANLAG
SLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATL
SNLMSATIAGFFIGLA

Specific function: Could be involved in pseudouridine transport [H]

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI11545853, Length=415, Percent_Identity=33.4939759036145, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI42542381, Length=418, Percent_Identity=32.2966507177034, Blast_Score=225, Evalue=7e-59,
Organism=Homo sapiens, GI227116277, Length=419, Percent_Identity=30.0715990453461, Blast_Score=200, Evalue=2e-51,
Organism=Escherichia coli, GI1788488, Length=416, Percent_Identity=99.0384615384615, Blast_Score=803, Evalue=0.0,
Organism=Escherichia coli, GI1788485, Length=416, Percent_Identity=87.7403846153846, Blast_Score=706, Evalue=0.0,
Organism=Escherichia coli, GI1788737, Length=412, Percent_Identity=30.5825242718447, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17560276, Length=396, Percent_Identity=28.2828282828283, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71991794, Length=399, Percent_Identity=29.0726817042606, Blast_Score=190, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI25146537, Length=194, Percent_Identity=28.8659793814433, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45552517, Length=408, Percent_Identity=31.1274509803922, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI19921868, Length=408, Percent_Identity=31.1274509803922, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI45552519, Length=408, Percent_Identity=31.1274509803922, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI281360430, Length=407, Percent_Identity=31.2039312039312, Blast_Score=196, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43517; Mature: 43517

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIMRSLVGMVVLLAIAFLLSVNKKRISVRTVGAALLLQIAIGGIMLYFPPGKWAVEQAA
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHH
LGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGV
HHHHHHHHCCCCCCCEEEHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDRMNRNELFTAICSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHH
MASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCCCCC
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFSNASLESIFGY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFAL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEHHHHHHHHHHH
CGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA
HCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIMRSLVGMVVLLAIAFLLSVNKKRISVRTVGAALLLQIAIGGIMLYFPPGKWAVEQAA
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHH
LGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGV
HHHHHHHHCCCCCCCEEEHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDRMNRNELFTAICSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHH
MASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCCCCC
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFSNASLESIFGY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFAL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEHHHHHHHHHHH
CGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA
HCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]