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The map label for this gene is yehY [H]

Identifier: 218549545

GI number: 218549545

Start: 2272024

End: 2273181

Strand: Reverse

Name: yehY [H]

Synonym: EFER_2217

Alternate gene names: 218549545

Gene position: 2273181-2272024 (Counterclockwise)

Preceding gene: 218549546

Following gene: 218549544

Centisome position: 49.54

GC content: 57.25

Gene sequence:

>1158_bases
GTGACTTATTTCCGTATTAATCCTGTTCTGGCGCTGCTGCTGTTGCTGACGGCAATCGCAGCGGCGCTGCCGTTTATCAG
TTACGCGCCTAATCGTTTAGTCTCGGGTGAGGGGCGTCATCTCTGGCAGTTGTGGCCGCAAACGATCTGGATGCTGGTGG
GCGTATGTTGCGCCTGGCTGACAGCCTGTTTTATTCCCGGTAGAAAAGGCAGCATTTTTGCACTCATTCTGGCGCAATTC
GTCTTCATATTGCTGGTGTGGGGCGCGGGAAAGGCGGCGACACAACTGGCGCAAAATGGCAGTGCACTGGCGCGTACCAG
CCTCGGCAGTGGTTTCTGGCTGGCTGCGGCGCTGGCATTGCTGGCCTGTAGCGATGCCATCCGCCGAATCTCCACGCATC
CGCTGTGGCGCTGGTTGTTGCATATGCAGATTGCCATTATTCCGCTGTGGTTGCTGTACTCCGGTACGCTTAACGATCTC
TCGCTAATGAAAGAATACGCCAACCGTCAGGATGTGTTTAATGACGCGCTGGCGCAACATCTGACGTTGCTGTTTGGTGC
GGTGCTGCCTGCGTTAGTGATTGGTGTGCCGCTGGGCGTCTGGTGCTACTTTTCCACTGCGCGGCAGGGGGCGATTTTTT
CTCTGCTGAATGTCATTCAGACCGTGCCTTCGGTGGCGCTCTTTGGCCTGTTGATTGCGCCGCTTGCCGCGCTGGTTACG
GCCTTTCCGTGGCTGGGTAAGCTCGGCATAGCAGGAACCGGAATGACACCCGCACTGATTGCGCTGGTGCTCTATGCCTT
GCTGCCGCTGGTGCGCGGTGTGGTAGTCGGCTTGAACCAGATCCCGCGCGATGTGCTGGAGAGCGCCAGAGCGATGGGCT
TGAACGGAGCACAGCGATTCCTGCATGTGCAGCTACCGCTGGCGTTACCGGTATTTCTGCGCAGCCTGCGGGTGGTGATG
GTGCAAACCGTCGGCATGACGGTGATTGCGGCATTAATCGGCGCAGGCGGTTTTGGTGCGTTGGTTTTCCAGGGGCTGCT
AAGCAGTGCCATTGATTTAGTGTTGCTGGGGGTGATCCCGGTAATCGTACTGGCGGTGCTGATCGACGCACTGTTCGATC
TGGTTATCGCACTGCTGAAGGTGAAACGTAATGATTGA

Upstream 100 bases:

>100_bases
GTTACAGCAACTGAATGCCAGCATTGCCGTTGAAGGACTGGATGCCAAAAAAGTGGCTACCGACTACCTGAAACAAAAAG
GGTGGACGAAGTAATTTCCC

Downstream 100 bases:

>100_bases
ATTTAGCCATGTCAGCAAACTGTTCGGCACACAAAAAGCCGTTAACGATCTCAATCTCAATTTTCAGGAAGGGAGTTTTT
CGGTGCTGATTGGCACATCT

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTYFRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQLWPQTIWMLVGVCCAWLTACFIPGRKGSIFALILAQF
VFILLVWGAGKAATQLAQNGSALARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDL
SLMKEYANRQDVFNDALAQHLTLLFGAVLPALVIGVPLGVWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAPLAALVT
AFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGLNGAQRFLHVQLPLALPVFLRSLRVVM
VQTVGMTVIAALIGAGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLIDALFDLVIALLKVKRND

Sequences:

>Translated_385_residues
MTYFRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQLWPQTIWMLVGVCCAWLTACFIPGRKGSIFALILAQF
VFILLVWGAGKAATQLAQNGSALARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDL
SLMKEYANRQDVFNDALAQHLTLLFGAVLPALVIGVPLGVWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAPLAALVT
AFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGLNGAQRFLHVQLPLALPVFLRSLRVVM
VQTVGMTVIAALIGAGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLIDALFDLVIALLKVKRND
>Mature_384_residues
TYFRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQLWPQTIWMLVGVCCAWLTACFIPGRKGSIFALILAQFV
FILLVWGAGKAATQLAQNGSALARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDLS
LMKEYANRQDVFNDALAQHLTLLFGAVLPALVIGVPLGVWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAPLAALVTA
FPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGLNGAQRFLHVQLPLALPVFLRSLRVVMV
QTVGMTVIAALIGAGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLIDALFDLVIALLKVKRND

Specific function: May be part of an ABC transporter complex involved in uptake of osmoprotectant molecules. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=385, Percent_Identity=96.8831168831169, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI1789033, Length=184, Percent_Identity=30.9782608695652, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788449, Length=250, Percent_Identity=31.6, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41320; Mature: 41189

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYFRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQLWPQTIWMLVGVCCAWL
CCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TACFIPGRKGSIFALILAQFVFILLVWGAGKAATQLAQNGSALARTSLGSGFWLAAALAL
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHH
LACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDLSLMKEYANRQDVFNDALAQH
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LTLLFGAVLPALVIGVPLGVWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAPLAALVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGLNGAQRF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHH
LHVQLPLALPVFLRSLRVVMVQTVGMTVIAALIGAGGFGALVFQGLLSSAIDLVLLGVIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIVLAVLIDALFDLVIALLKVKRND
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYFRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQLWPQTIWMLVGVCCAWL
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TACFIPGRKGSIFALILAQFVFILLVWGAGKAATQLAQNGSALARTSLGSGFWLAAALAL
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHH
LACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDLSLMKEYANRQDVFNDALAQH
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LTLLFGAVLPALVIGVPLGVWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAPLAALVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGLNGAQRF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHH
LHVQLPLALPVFLRSLRVVMVQTVGMTVIAALIGAGGFGALVFQGLLSSAIDLVLLGVIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIVLAVLIDALFDLVIALLKVKRND
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]