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The map label for this gene is mrp [H]

Identifier: 218549527

GI number: 218549527

Start: 2242805

End: 2243914

Strand: Reverse

Name: mrp [H]

Synonym: EFER_2198

Alternate gene names: 218549527

Gene position: 2243914-2242805 (Counterclockwise)

Preceding gene: 218549538

Following gene: 218549526

Centisome position: 48.9

GC content: 54.95

Gene sequence:

>1110_bases
ATGAACGAACAATCCCAGGCCAAATCACCAGAAGCCCTGCGCGCAATGGTCGCCGGGACACTGGCCAATTTTCAGCACCC
AACCCTCAAGCATAACCTCACCACGCTGAAAGCGTTGCACCATGTCGCCTGGATGGACGACACGCTGCATGTGGAACTGG
TTATGCCGTTTGTCTGGCATAGCGCGTTCGAAGAGTTAAAAGAGCAATGTAGCGCCGAGTTGCTGCGTATCACCGGGGCG
AAAGCTATTGACTGGAAATTGTCGCATAACATCGCCACTCTGAAACGCGTGAAGAATCAGCCGGGTATTAACGGCGTGAA
GAACATTATCGCGGTGAGCTCCGGTAAAGGCGGCGTGGGTAAATCGTCCACGGCGGTAAACCTGGCACTGGCGCTGGCGG
CAGAAGGGGCGAAAGTCGGCATTCTGGACGCCGATATCTACGGCCCATCAATCCCAACCATGCTGGGTGCAGAAAATCAG
CGTCCGACCTCGCCAGACGGCACCCACATGGCGCCGATTATGTCTCATGGCCTGGCAACCAACTCGATTGGTTATCTGGT
CACTGATGATAACGCGATGGTGTGGCGTGGCCCGATGGCGAGCAAGGCGTTAATGCAGATGTTGCAGGAAACGTTGTGGC
CAGATCTCGACTATCTGGTGCTTGATATGCCGCCAGGCACCGGTGATATCCAGCTGACACTGGCACAGAACATTCCGGTG
ACCGGGGCGGTAGTGGTCACCACGCCGCAGGATATCGCGCTGATCGATGCGAAAAAAGGCATTGTGATGTTCGAGAAGGT
CGAAGTTCCGGTGCTCGGTATTGTCGAGAACATGAGTGTGCATATTTGCAGTAACTGCGGTCACCATGAGCCGATTTTCG
GTACCGGTGGTGCAGAGAAACTGGCTGAGAAATATCACACGCAGTTGCTGGGGCAGATGCCGTTACACATTTCCTTACGT
GAAGATCTCGATAAAGGCACGCCAACAGTTATCAGCCGTCCGGAGAGCGAATTTACCGCTATCTACCGCCAGCTGGCTGA
CCGCGTTGCAGCCCAGCTTTATTGGCAGGGAGAAGTGATCCCTGGCGAAATTGCCTTCCGCGCTCTTTGA

Upstream 100 bases:

>100_bases
CCTGTGCAAGCATCTTATGATGCATTATTAGGTAAGTACTTAGCTGTTAACTTCAGGTAAACTAATAGCGATAAGTTATC
TTTATAAATAAGGAGTCGGG

Downstream 100 bases:

>100_bases
TTTCCTCTCTATTATTCCCACCGCGTCAATGTAATGTTGACGCGGTGTTTCGTTTTGCTGCCTTGCCGGGCGTTAATCCT
AAAAATTACGCTGCAAATTG

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAWMDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGA
KAIDWKLSHNIATLKRVKNQPGINGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQLTLAQNIPV
TGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVENMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLR
EDLDKGTPTVISRPESEFTAIYRQLADRVAAQLYWQGEVIPGEIAFRAL

Sequences:

>Translated_369_residues
MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAWMDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGA
KAIDWKLSHNIATLKRVKNQPGINGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQLTLAQNIPV
TGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVENMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLR
EDLDKGTPTVISRPESEFTAIYRQLADRVAAQLYWQGEVIPGEIAFRAL
>Mature_369_residues
MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAWMDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGA
KAIDWKLSHNIATLKRVKNQPGINGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQLTLAQNIPV
TGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVENMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLR
EDLDKGTPTVISRPESEFTAIYRQLADRVAAQLYWQGEVIPGEIAFRAL

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=280, Percent_Identity=48.2142857142857, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI118572611, Length=252, Percent_Identity=39.2857142857143, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI6912540, Length=259, Percent_Identity=39.3822393822394, Blast_Score=170, Evalue=2e-42,
Organism=Escherichia coli, GI87082045, Length=369, Percent_Identity=99.4579945799458, Blast_Score=758, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25143050, Length=265, Percent_Identity=40, Blast_Score=185, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6322188, Length=261, Percent_Identity=37.1647509578544, Blast_Score=180, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6321347, Length=241, Percent_Identity=39.0041493775934, Blast_Score=161, Evalue=1e-40,
Organism=Drosophila melanogaster, GI221511043, Length=259, Percent_Identity=40.5405405405405, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24667611, Length=260, Percent_Identity=37.6923076923077, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI19921440, Length=233, Percent_Identity=37.3390557939914, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 39937; Mature: 39937

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAWMDDTLHVELVMPFVWH
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHH
SAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPGINGVKNIIAVSSGKGGVG
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHEEEEECCCCCCC
KSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQRPTSPDGTHMAPIMSHGLAT
CCCHHHEEEEEEECCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCEEHHHHHCCCCC
NSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQLTLAQNIPV
CCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCC
TGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVENMSVHICSNCGHHEPIFGTGGAEK
CCEEEEECCCCEEEEECCCCEEEEEEECCCEEEEECCCEEEEECCCCCCCCEECCCCHHH
LAEKYHTQLLGQMPLHISLREDLDKGTPTVISRPESEFTAIYRQLADRVAAQLYWQGEVI
HHHHHHHHHHHCCCEEEEEHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHEEECCCCC
PGEIAFRAL
CCHHEEECC
>Mature Secondary Structure
MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAWMDDTLHVELVMPFVWH
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHH
SAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPGINGVKNIIAVSSGKGGVG
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHEEEEECCCCCCC
KSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQRPTSPDGTHMAPIMSHGLAT
CCCHHHEEEEEEECCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCEEHHHHHCCCCC
NSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQLTLAQNIPV
CCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCC
TGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVENMSVHICSNCGHHEPIFGTGGAEK
CCEEEEECCCCEEEEECCCCEEEEEEECCCEEEEECCCEEEEECCCCCCCCEECCCCHHH
LAEKYHTQLLGQMPLHISLREDLDKGTPTVISRPESEFTAIYRQLADRVAAQLYWQGEVI
HHHHHHHHHHHCCCEEEEEHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHEEECCCCC
PGEIAFRAL
CCHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]