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The map label for this gene is yniC [H]

Identifier: 218549502

GI number: 218549502

Start: 2212277

End: 2212975

Strand: Reverse

Name: yniC [H]

Synonym: EFER_2173

Alternate gene names: 218549502

Gene position: 2212975-2212277 (Counterclockwise)

Preceding gene: 218549503

Following gene: 218549490

Centisome position: 48.23

GC content: 46.92

Gene sequence:

>699_bases
ATGATGACAAGCCTGGCGTGGTGCCAGGCTTTATTGCGAGGAACAATGTTTAATTGTAAAGCAGTCATTTTTGATATGGA
CGGTGTCATCATTGATTCGGAAGGGTTATGGCGTCAGGCACAAAAGGGAGCACTGGTAAGGTGGGGCACACGTGTCAGTG
ACGAAGAGTGTATAAGACTGACTAAAGGTAAAAGGCTGGATGAGATTGCCCAAACCTGGTGTGAATATTGTCATTTACAC
ATTGAACCCGCACTGCTGGAAAGTGAGATTCGCCGCCTGATCACTACGTTGATTGCCGGGACGGGCGAAGCGATGCCAGG
CGTTCAGGACGTGTTATCTTTTTTGCGCCGGAGTGGCTATCAACTGGCGCTGGCAACCTCTTCATCTTACCAGGTGATCG
ATGCTGTACTGACAAAACTCAATATTCAGCACTATTTTTCAGTGATTTGTAGTGCTGATGATGAAAACCATGGGAAACCA
CATCCGGCCGTTTATCTTTCTGCTCTGCGAGAATTACAACTGTCTGCTGCAGATTGTTTAGTTATAGAGGACAGTTTGAG
TGGTTTTCAGGCAGCACAGGCGGCAGGAATAAACACCATTGTGGTATCGGAAGATGCCCAACAATGCTGCTTTAATGCGG
CGAGTGCAAGATATTTATCGATGTATGAATTACTGGCAGCGTTAGCCGTAGCTGCGTAA

Upstream 100 bases:

>100_bases
TGTATGTGATAGCGTTTATTATTTGCCCTTTTATTCGCGTCGAACAACCGGGATTCTCAAATCAGCAAGTGTGTGAAGGG
AAGACCGCCACCATTTCCTG

Downstream 100 bases:

>100_bases
CAAAAAATGGTGAGCGCAGAAGATCCCAGGGATGATGCCGGTCTGCTAATCCTGCTTCTGCGCTTGCTTTTATTTAACGT
AAAAGCGGGCAATCTGGTGG

Product: phosphoglycolate phosphatase

Products: glycerol; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MMTSLAWCQALLRGTMFNCKAVIFDMDGVIIDSEGLWRQAQKGALVRWGTRVSDEECIRLTKGKRLDEIAQTWCEYCHLH
IEPALLESEIRRLITTLIAGTGEAMPGVQDVLSFLRRSGYQLALATSSSYQVIDAVLTKLNIQHYFSVICSADDENHGKP
HPAVYLSALRELQLSAADCLVIEDSLSGFQAAQAAGINTIVVSEDAQQCCFNAASARYLSMYELLAALAVAA

Sequences:

>Translated_232_residues
MMTSLAWCQALLRGTMFNCKAVIFDMDGVIIDSEGLWRQAQKGALVRWGTRVSDEECIRLTKGKRLDEIAQTWCEYCHLH
IEPALLESEIRRLITTLIAGTGEAMPGVQDVLSFLRRSGYQLALATSSSYQVIDAVLTKLNIQHYFSVICSADDENHGKP
HPAVYLSALRELQLSAADCLVIEDSLSGFQAAQAAGINTIVVSEDAQQCCFNAASARYLSMYELLAALAVAA
>Mature_232_residues
MMTSLAWCQALLRGTMFNCKAVIFDMDGVIIDSEGLWRQAQKGALVRWGTRVSDEECIRLTKGKRLDEIAQTWCEYCHLH
IEPALLESEIRRLITTLIAGTGEAMPGVQDVLSFLRRSGYQLALATSSSYQVIDAVLTKLNIQHYFSVICSADDENHGKP
HPAVYLSALRELQLSAADCLVIEDSLSGFQAAQAAGINTIVVSEDAQQCCFNAASARYLSMYELLAALAVAA

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates 2-deoxyglucose 6-phosphate and mannose 6- phosphate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=188, Percent_Identity=30.8510638297872, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI207113149, Length=210, Percent_Identity=29.0476190476191, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788021, Length=211, Percent_Identity=30.8056872037915, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789046, Length=182, Percent_Identity=31.3186813186813, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789787, Length=237, Percent_Identity=26.1603375527426, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790151, Length=194, Percent_Identity=24.7422680412371, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554716, Length=195, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137324, Length=192, Percent_Identity=28.6458333333333, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI20129151, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI20129149, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550097, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.21

Molecular weight: Translated: 25453; Mature: 25453

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTSLAWCQALLRGTMFNCKAVIFDMDGVIIDSEGLWRQAQKGALVRWGTRVSDEECIRL
CCCHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCHHHHHHCCCEEECCCCCCHHHHHHH
TKGKRLDEIAQTWCEYCHLHIEPALLESEIRRLITTLIAGTGEAMPGVQDVLSFLRRSGY
HCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
QLALATSSSYQVIDAVLTKLNIQHYFSVICSADDENHGKPHPAVYLSALRELQLSAADCL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
VIEDSLSGFQAAQAAGINTIVVSEDAQQCCFNAASARYLSMYELLAALAVAA
EEECCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMTSLAWCQALLRGTMFNCKAVIFDMDGVIIDSEGLWRQAQKGALVRWGTRVSDEECIRL
CCCHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCHHHHHHCCCEEECCCCCCHHHHHHH
TKGKRLDEIAQTWCEYCHLHIEPALLESEIRRLITTLIAGTGEAMPGVQDVLSFLRRSGY
HCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
QLALATSSSYQVIDAVLTKLNIQHYFSVICSADDENHGKPHPAVYLSALRELQLSAADCL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
VIEDSLSGFQAAQAAGINTIVVSEDAQQCCFNAASARYLSMYELLAALAVAA
EEECCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glycerol 1-phosphate; H2O

Specific reaction: glycerol 1-phosphate + H2O = glycerol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]