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The map label for this gene is udk [H]

Identifier: 218549483

GI number: 218549483

Start: 2185309

End: 2185950

Strand: Reverse

Name: udk [H]

Synonym: EFER_2152

Alternate gene names: 218549483

Gene position: 2185950-2185309 (Counterclockwise)

Preceding gene: 218549485

Following gene: 218549482

Centisome position: 47.64

GC content: 47.2

Gene sequence:

>642_bases
ATGACTGATCAGTCTCATCAGTGCGTCATTATCGGTATCGCTGGCGCATCGGCTTCCGGCAAGAGTCTTATTGCCAGTAC
CCTTTATCGTGAACTGCGTGAACAAGTGGGCGATGAACACATCGGCGTTATTCCGGAAGATTGCTACTACAAAGATCAAA
GCCATCTGTCGATGGAAGAGCGGGTTAAAACTAATTATGACCATCCCAGCGCGATGGATCATAGCCTGCTTCTTGAACAT
CTTCAGGCACTTAAACGTGGCTCGGCCATTGACCTGCCGGTTTACAGTTACGTAGAACACACGCGAATGAAAGAAACGGT
GAAGGTTGAACCGAAGAAAGTCATCATTCTCGAAGGCATCTTATTGCTGACAGATGCACGGCTGCGTGACGAATTGAATT
TCTCTATTTTTGTCGATACTCCGCTGGATATCTGCCTGATGCGCCGCATCAAGCGCGACGTTAATGAGCGTGGTCGTTCG
ATGGATTCCGTGATGGCGCAATATCAAAAAACTGTGCGCCCGATGTTCCTGCAATTTATTGAACCTTCCAAGCAATATGC
GGATATTATCGTGCCGCGCGGCGGGAAAAACCGCATCGCGATCGATATATTGAAAGCAAAAATTAGTCAGTTCTTTGAAT
AA

Upstream 100 bases:

>100_bases
TATTCGACTGGTATCAGACGGATGAAATCCCTATAATTGCCGCGTTTGGCGTTTCGACGCTCCCCTTCCTAACATCCAGG
TTATTCAGGTCGCTAAATAT

Downstream 100 bases:

>100_bases
GTTTTGTGAATTGTGTACCGTTCAGTGATAACCTGGTATGCCCTTGACGCAAAAGGCGTTAAGGGAGTGATGCGCGAAAG
GAGAAAGTGCCATGCGTCTG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEH
LQALKRGSAIDLPVYSYVEHTRMKETVKVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Sequences:

>Translated_213_residues
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEH
LQALKRGSAIDLPVYSYVEHTRMKETVKVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
>Mature_212_residues
TDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHL
QALKRGSAIDLPVYSYVEHTRMKETVKVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRSM
DSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=217, Percent_Identity=36.405529953917, Blast_Score=158, Evalue=4e-39,
Organism=Homo sapiens, GI57863312, Length=203, Percent_Identity=38.9162561576355, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI301129207, Length=203, Percent_Identity=38.9162561576355, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI13899253, Length=211, Percent_Identity=35.5450236966825, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI209863022, Length=159, Percent_Identity=32.7044025157233, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI87082034, Length=213, Percent_Identity=99.5305164319249, Blast_Score=437, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17539892, Length=207, Percent_Identity=37.6811594202899, Blast_Score=148, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17539894, Length=207, Percent_Identity=37.6811594202899, Blast_Score=148, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71981181, Length=216, Percent_Identity=34.2592592592593, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324339, Length=150, Percent_Identity=34.6666666666667, Blast_Score=111, Evalue=7e-26,
Organism=Drosophila melanogaster, GI45550449, Length=203, Percent_Identity=38.9162561576355, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI28573516, Length=203, Percent_Identity=38.9162561576355, Blast_Score=149, Evalue=9e-37,
Organism=Drosophila melanogaster, GI28573514, Length=203, Percent_Identity=38.9162561576355, Blast_Score=149, Evalue=9e-37,
Organism=Drosophila melanogaster, GI28573512, Length=203, Percent_Identity=38.9162561576355, Blast_Score=149, Evalue=9e-37,
Organism=Drosophila melanogaster, GI221458995, Length=219, Percent_Identity=35.1598173515982, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24649624, Length=218, Percent_Identity=34.8623853211009, Blast_Score=147, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 24381; Mature: 24249

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEE
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHCCHHH
RVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTRMKETVKVEPKKVIILEGI
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCEEEEEHHH
LLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFI
HHHHCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEE
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHCCHHH
RVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTRMKETVKVEPKKVIILEGI
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCEEEEEHHH
LLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFI
HHHHCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]