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The map label for this gene is sbmC [H]

Identifier: 218549362

GI number: 218549362

Start: 2078962

End: 2079429

Strand: Reverse

Name: sbmC [H]

Synonym: EFER_2030

Alternate gene names: 218549362

Gene position: 2079429-2078962 (Counterclockwise)

Preceding gene: 218549365

Following gene: 218549361

Centisome position: 45.32

GC content: 46.15

Gene sequence:

>468_bases
ATGGATTACGAGATTAAGCAAGAGAAGAAACGCACTATTGCCGGGTTCCATCTGGTTGGACCGTGGGAAAAAACGGTAAA
GCAAGGTTTTGATCAGCTCATGATGTGGGTTGAGAATCATAACATTGAGCCGCTGGAGTGGGTCGCTGTCTATTACGATA
ACCCGGACGAGGTGCCTGCAGAAAAATTACGTTGCGATACAGTGGTGACCGTGCCAGAGAATTTTTGTCTGCCGGAAAAC
AGTGAAGGGGTGAACGTCACTGAAATTGCGGGTGGACAATATGCCGTTACTGTTGCCCGTGTTCAGGGGCATGATTTCGG
CACGCCATGGTATCAATTTATTAATAGCTTGCTGGAAGATTCTCAGTATCAGATGGCCCACAAACCGTGCTTTGAGGTTT
ATTTAAACAATGGTGCTGTCGATGGTTACTGGGATATCGAAATGTATGTACCGGTACTGCCTAAATAA

Upstream 100 bases:

>100_bases
TGGCACATGTGCGAGACTGCTCACATAATAATCACTATTTTGTTGTGATTTTGGTTCATCTCATTCACTGTATGAAAACA
CAGTAAATGACGGAGGAAGT

Downstream 100 bases:

>100_bases
TGGCGCAGATCAACACAGAGCGGGTTAAAGCTGCCCGCTCTGCTGTCATTCAGTTAGTGAATATGAGTACAATTGCGCAT
TCGTAATTCCTTCGGGAGTG

Product: DNA gyrase inhibitor

Products: NA

Alternate protein names: Protein sbmC [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MDYEIKQEKKRTIAGFHLVGPWEKTVKQGFDQLMMWVENHNIEPLEWVAVYYDNPDEVPAEKLRCDTVVTVPENFCLPEN
SEGVNVTEIAGGQYAVTVARVQGHDFGTPWYQFINSLLEDSQYQMAHKPCFEVYLNNGAVDGYWDIEMYVPVLPK

Sequences:

>Translated_155_residues
MDYEIKQEKKRTIAGFHLVGPWEKTVKQGFDQLMMWVENHNIEPLEWVAVYYDNPDEVPAEKLRCDTVVTVPENFCLPEN
SEGVNVTEIAGGQYAVTVARVQGHDFGTPWYQFINSLLEDSQYQMAHKPCFEVYLNNGAVDGYWDIEMYVPVLPK
>Mature_155_residues
MDYEIKQEKKRTIAGFHLVGPWEKTVKQGFDQLMMWVENHNIEPLEWVAVYYDNPDEVPAEKLRCDTVVTVPENFCLPEN
SEGVNVTEIAGGQYAVTVARVQGHDFGTPWYQFINSLLEDSQYQMAHKPCFEVYLNNGAVDGYWDIEMYVPVLPK

Specific function: Inhibits the supercoiling activity of DNA gyrase. Protects cells from the DNA replication inhibitor microcin B17 (MccB17). Blocks MccB17 export from producing cells [H]

COG id: COG3449

COG function: function code L; DNA gyrase inhibitor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788319, Length=155, Percent_Identity=79.3548387096774, Blast_Score=258, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010499
- InterPro:   IPR011256 [H]

Pfam domain/function: PF06445 AraC_E_bind [H]

EC number: NA

Molecular weight: Translated: 17894; Mature: 17894

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYEIKQEKKRTIAGFHLVGPWEKTVKQGFDQLMMWVENHNIEPLEWVAVYYDNPDEVPA
CCCCCCHHHHHEECCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCH
EKLRCDTVVTVPENFCLPENSEGVNVTEIAGGQYAVTVARVQGHDFGTPWYQFINSLLED
HHCCCCEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHCC
SQYQMAHKPCFEVYLNNGAVDGYWDIEMYVPVLPK
CHHHHHHCCEEEEEECCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure
MDYEIKQEKKRTIAGFHLVGPWEKTVKQGFDQLMMWVENHNIEPLEWVAVYYDNPDEVPA
CCCCCCHHHHHEECCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCH
EKLRCDTVVTVPENFCLPENSEGVNVTEIAGGQYAVTVARVQGHDFGTPWYQFINSLLED
HHCCCCEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHCC
SQYQMAHKPCFEVYLNNGAVDGYWDIEMYVPVLPK
CHHHHHHCCEEEEEECCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8709849; 9097040; 9278503; 9442027 [H]