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The map label for this gene is maoC [H]

Identifier: 218548961

GI number: 218548961

Start: 1652480

End: 1654525

Strand: Direct

Name: maoC [H]

Synonym: EFER_1609

Alternate gene names: 218548961

Gene position: 1652480-1654525 (Clockwise)

Preceding gene: 218548941

Following gene: 218548962

Centisome position: 36.01

GC content: 53.52

Gene sequence:

>2046_bases
ATGCAGCAGTTAGCCAGTTTCTTATCCGGTACCTGGCAGTCTGGCCGGGGCCGTAGCCGTTTGATTCACCACGCCATTAG
CGGCGAGGCGTTATGGGAAGTGACCAGTGAAGGTCTTGATATGGCGGCTGCCCGCCAGTTTGCCATTGAAAAAGGTGCCC
CCGCCCTCCGCGCTATGACCTTTATCGAACGTGCGGCGATGCTTAAAGCGGTCGCTAAACATCTGCTGAGTGAAAAAGAG
CGCTTCTATGCTCTTTCTGCACAGACAGGCGCAACGCGGGCAGACAGTTGGGTTGATATTGAAGGTGGCATTGGGACGTT
ATTTACTTACGCCAGCCTCGGTAGCCGGGAGCTGCCTGACGATACGCTGTGGCCGGAAGATGAATTGATACCCTTATCGA
AAGAAGGTGGATTTGCTGCACGCCATGTACTGACCTCGAAGTCAGGCGTGGCAGTGCATATTAACGCCTTTAACTTCCCC
TGCTGGGGAATGCTGGAAAAGCTGGCTCCAACGTGGCTGGGTGGGATGCCTGCCATCATCAAACCAGCCACCGCGACGGC
CCAACTGACTCAGGCGATGGTGAAATCAATTGTCGATAGCGGTCTTGTTCCCGAAGGCGCAATTAGTCTGATCTGCGGTA
GTGCGGGTGATCTGTTGGACCATCTGGACAGCCAGGATGTGGTGACTTTCACGGGGTCTGCGACGACCGGACAGATGCTG
CGAGTTCAGCCAAATATCGTTGCCAAATCTATCCCCTTCACTATGGAAGCTGATTCCCTGAACTGCTGTGTACTGGGCGA
AGATATCACCCCGGATCAACCGGAGTTTGCACTGTTTATTCGTGAAGTTGTGCGTGAGATGACCACAAAAGCCGGGCAAA
AATGTACGGCAATCCGGCGGATTATTGTGCCGCAGGCATTGGTTAATGCTGTCAGTGATGCTCTGGTTGCGCGATTACAG
AAAGTCGTGGTCGGTGATCCTGCGCAGGAAGGCGTGAAAATGGGCGCACTGGTAAATGCTGAGCAACGTGCCGATGTGCA
GGAAAAAGTGAACACATTGCTGGCTGCAGGATGCGAGATTCGCCTCGGTGGTCATGCGGATTTATCTGCTGCGGGTGCAT
TCTTCCCGCCAACCTTATTGTACTGTCCGCAGCCGGACGAAACACCGGCGGTACATGCAACAGAAGCCTTTGGCCCTGTC
GCAACGCTGATGCCAGCACAAAACCAGCAACATGCTCTGCAACTGGCTTGTGCAGGCGGCGGTAGCCTTGCAGGAACGCT
GGTGACGGCTGATCCGCAAATTGCGCGCCAGTTTATTGCCGAAGCGGCACGTGCGCATGGGCGAATTCAGATCCTCAATG
AAGAATCGGCAAAAGAATCCACCGGGCATGGCTCCCCACTGCCACAACTGGTACATGGTGGGCCTGGTCGCGCAGGAGGC
GGTGAAGAATTAGGTGGTTTACGAGCGGTAAAACATTACATGCAGCGAACCGCTGTTCAGGGTAGTCCAACGATGCTTGC
CGCTATCAGTAAACAGTGGGTGCGTGGTGCGAAAGTCGAAGAAAATCGTATTCATCCGTTCCGCAAATATTTTGAGGAGC
TACAACCAGGCGACAGCCTGCTGACTCCCCGCCGCACAATGACAGAGGCCGATATTGTTAACTTTGCTTGCCTCAGCGGC
GATCATTTCTATGCACATATGGATAAGATTGCTGCTGCCGAATCTTTTTTTGGTGAGCGTGTGGTACATGGATATTTTGT
GCTTTCTGCGGCTGCGGGTCTGTTTGTCGATGCCGGTGTCGGTCCGGTCATTGCTAACTACGGGCTGGAAAACTTGCGCT
TTATCGAGCCCGTAAAACCAGGCGATACCATCCAGGTGCGTCTCACCTGTAAGCGCAAAACACTGAAAAAACAGCGTAAT
GCAGAAGAAAAACCAACAGGTGTTGTGGAATGGGCGGTAGAGGTATTCAATCAGCATCAAACCCCGGTGGCGCTGTATTC
AATTCTGACGCTGGTGGCCAGGCAGCACGGTGATTTTGTCGATTAA

Upstream 100 bases:

>100_bases
ACAGATCGCATAGTTAACATTTCGTTAAAAGACACCTTGCTTTTTATGATTCGTGATTTAACTATTAGCAACAGAAATGT
GAAACATCTGGAGAGTAGCG

Downstream 100 bases:

>100_bases
TCAGTGAATGAAGGGCAACGGCGAATAGTTGCCCTTTTATTTCACTCAATTTTGTGACGTTGTCACATTATGCCTGGTGT
GTATATCTTTTTTCAGGGCA

Product: bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase

Products: NA

Alternate protein names: Phenylacetic acid degradation protein paaZ [H]

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAARQFAIEKGAPALRAMTFIERAAMLKAVAKHLLSEKE
RFYALSAQTGATRADSWVDIEGGIGTLFTYASLGSRELPDDTLWPEDELIPLSKEGGFAARHVLTSKSGVAVHINAFNFP
CWGMLEKLAPTWLGGMPAIIKPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDLLDHLDSQDVVTFTGSATTGQML
RVQPNIVAKSIPFTMEADSLNCCVLGEDITPDQPEFALFIREVVREMTTKAGQKCTAIRRIIVPQALVNAVSDALVARLQ
KVVVGDPAQEGVKMGALVNAEQRADVQEKVNTLLAAGCEIRLGGHADLSAAGAFFPPTLLYCPQPDETPAVHATEAFGPV
ATLMPAQNQQHALQLACAGGGSLAGTLVTADPQIARQFIAEAARAHGRIQILNEESAKESTGHGSPLPQLVHGGPGRAGG
GEELGGLRAVKHYMQRTAVQGSPTMLAAISKQWVRGAKVEENRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSG
DHFYAHMDKIAAAESFFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLENLRFIEPVKPGDTIQVRLTCKRKTLKKQRN
AEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQHGDFVD

Sequences:

>Translated_681_residues
MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAARQFAIEKGAPALRAMTFIERAAMLKAVAKHLLSEKE
RFYALSAQTGATRADSWVDIEGGIGTLFTYASLGSRELPDDTLWPEDELIPLSKEGGFAARHVLTSKSGVAVHINAFNFP
CWGMLEKLAPTWLGGMPAIIKPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDLLDHLDSQDVVTFTGSATTGQML
RVQPNIVAKSIPFTMEADSLNCCVLGEDITPDQPEFALFIREVVREMTTKAGQKCTAIRRIIVPQALVNAVSDALVARLQ
KVVVGDPAQEGVKMGALVNAEQRADVQEKVNTLLAAGCEIRLGGHADLSAAGAFFPPTLLYCPQPDETPAVHATEAFGPV
ATLMPAQNQQHALQLACAGGGSLAGTLVTADPQIARQFIAEAARAHGRIQILNEESAKESTGHGSPLPQLVHGGPGRAGG
GEELGGLRAVKHYMQRTAVQGSPTMLAAISKQWVRGAKVEENRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSG
DHFYAHMDKIAAAESFFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLENLRFIEPVKPGDTIQVRLTCKRKTLKKQRN
AEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQHGDFVD
>Mature_681_residues
MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAARQFAIEKGAPALRAMTFIERAAMLKAVAKHLLSEKE
RFYALSAQTGATRADSWVDIEGGIGTLFTYASLGSRELPDDTLWPEDELIPLSKEGGFAARHVLTSKSGVAVHINAFNFP
CWGMLEKLAPTWLGGMPAIIKPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDLLDHLDSQDVVTFTGSATTGQML
RVQPNIVAKSIPFTMEADSLNCCVLGEDITPDQPEFALFIREVVREMTTKAGQKCTAIRRIIVPQALVNAVSDALVARLQ
KVVVGDPAQEGVKMGALVNAEQRADVQEKVNTLLAAGCEIRLGGHADLSAAGAFFPPTLLYCPQPDETPAVHATEAFGPV
ATLMPAQNQQHALQLACAGGGSLAGTLVTADPQIARQFIAEAARAHGRIQILNEESAKESTGHGSPLPQLVHGGPGRAGG
GEELGGLRAVKHYMQRTAVQGSPTMLAAISKQWVRGAKVEENRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSG
DHFYAHMDKIAAAESFFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLENLRFIEPVKPGDTIQVRLTCKRKTLKKQRN
AEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQHGDFVD

Specific function: Phenylacetic acid aerobic catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=505, Percent_Identity=25.1485148514851, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI25777724, Length=497, Percent_Identity=23.7424547283702, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI12007648, Length=416, Percent_Identity=25, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI153266822, Length=490, Percent_Identity=22.8571428571429, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI25777732, Length=502, Percent_Identity=25.2988047808765, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI115387104, Length=448, Percent_Identity=23.6607142857143, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI25777728, Length=400, Percent_Identity=24, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI25777730, Length=503, Percent_Identity=25.4473161033797, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI4507229, Length=307, Percent_Identity=27.6872964169381, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI25777721, Length=321, Percent_Identity=26.791277258567, Blast_Score=67, Evalue=8e-11,
Organism=Escherichia coli, GI1787653, Length=681, Percent_Identity=98.2378854625551, Blast_Score=1377, Evalue=0.0,
Organism=Escherichia coli, GI87081926, Length=343, Percent_Identity=26.530612244898, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1787684, Length=402, Percent_Identity=25.8706467661692, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1789015, Length=456, Percent_Identity=24.780701754386, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786504, Length=511, Percent_Identity=25.0489236790607, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788042, Length=501, Percent_Identity=26.3473053892216, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082295, Length=275, Percent_Identity=24.7272727272727, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787715, Length=361, Percent_Identity=25.4847645429363, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787250, Length=404, Percent_Identity=22.2772277227723, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787558, Length=291, Percent_Identity=24.3986254295533, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25143874, Length=452, Percent_Identity=24.7787610619469, Blast_Score=109, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25143876, Length=452, Percent_Identity=24.7787610619469, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI115534176, Length=363, Percent_Identity=26.7217630853994, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562198, Length=421, Percent_Identity=24.9406175771971, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551164, Length=323, Percent_Identity=22.6006191950464, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71995606, Length=367, Percent_Identity=25.3405994550409, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995613, Length=367, Percent_Identity=25.3405994550409, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17534119, Length=293, Percent_Identity=25.938566552901, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324950, Length=355, Percent_Identity=23.3802816901408, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320917, Length=356, Percent_Identity=23.876404494382, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325196, Length=275, Percent_Identity=25.0909090909091, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129399, Length=511, Percent_Identity=25.2446183953033, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281362580, Length=302, Percent_Identity=25.1655629139073, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62472918, Length=302, Percent_Identity=25.1655629139073, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62472926, Length=302, Percent_Identity=25.1655629139073, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62472936, Length=302, Percent_Identity=25.1655629139073, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356737, Length=302, Percent_Identity=25.1655629139073, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR002539
- InterPro:   IPR011966 [H]

Pfam domain/function: PF00171 Aldedh; PF01575 MaoC_dehydratas [H]

EC number: NA

Molecular weight: Translated: 73073; Mature: 73073

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAARQFAIEKGAPALRAMT
CHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHH
FIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEGGIGTLFTYASLGSRELPD
HHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCC
DTLWPEDELIPLSKEGGFAARHVLTSKSGVAVHINAFNFPCWGMLEKLAPTWLGGMPAII
CCCCCCCCEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHC
KPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDLLDHLDSQDVVTFTGSATTGQML
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHCCCCCEEEEECCCCCCCEE
RVQPNIVAKSIPFTMEADSLNCCVLGEDITPDQPEFALFIREVVREMTTKAGQKCTAIRR
EECCCHHHCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
IIVPQALVNAVSDALVARLQKVVVGDPAQEGVKMGALVNAEQRADVQEKVNTLLAAGCEI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCHHHCCHHHHHHHHHHCCCEE
RLGGHADLSAAGAFFPPTLLYCPQPDETPAVHATEAFGPVATLMPAQNQQHALQLACAGG
EECCCCCCCCCCCCCCCCEEECCCCCCCCCEECHHHHCCHHHHCCCCCCCCEEEEEECCC
GSLAGTLVTADPQIARQFIAEAARAHGRIQILNEESAKESTGHGSPLPQLVHGGPGRAGG
CCEECEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCC
GEELGGLRAVKHYMQRTAVQGSPTMLAAISKQWVRGAKVEENRIHPFRKYFEELQPGDSL
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCC
LTPRRTMTEADIVNFACLSGDHFYAHMDKIAAAESFFGERVVHGYFVLSAAAGLFVDAGV
CCCCHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
GPVIANYGLENLRFIEPVKPGDTIQVRLTCKRKTLKKQRNAEEKPTGVVEWAVEVFNQHQ
CHHHHHCCCCCCEEECCCCCCCEEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
TPVALYSILTLVARQHGDFVD
CHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAARQFAIEKGAPALRAMT
CHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHH
FIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEGGIGTLFTYASLGSRELPD
HHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCC
DTLWPEDELIPLSKEGGFAARHVLTSKSGVAVHINAFNFPCWGMLEKLAPTWLGGMPAII
CCCCCCCCEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHC
KPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDLLDHLDSQDVVTFTGSATTGQML
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHCCCCCEEEEECCCCCCCEE
RVQPNIVAKSIPFTMEADSLNCCVLGEDITPDQPEFALFIREVVREMTTKAGQKCTAIRR
EECCCHHHCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
IIVPQALVNAVSDALVARLQKVVVGDPAQEGVKMGALVNAEQRADVQEKVNTLLAAGCEI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCHHHCCHHHHHHHHHHCCCEE
RLGGHADLSAAGAFFPPTLLYCPQPDETPAVHATEAFGPVATLMPAQNQQHALQLACAGG
EECCCCCCCCCCCCCCCCEEECCCCCCCCCEECHHHHCCHHHHCCCCCCCCEEEEEECCC
GSLAGTLVTADPQIARQFIAEAARAHGRIQILNEESAKESTGHGSPLPQLVHGGPGRAGG
CCEECEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCC
GEELGGLRAVKHYMQRTAVQGSPTMLAAISKQWVRGAKVEENRIHPFRKYFEELQPGDSL
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCC
LTPRRTMTEADIVNFACLSGDHFYAHMDKIAAAESFFGERVVHGYFVLSAAAGLFVDAGV
CCCCHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
GPVIANYGLENLRFIEPVKPGDTIQVRLTCKRKTLKKQRNAEEKPTGVVEWAVEVFNQHQ
CHHHHHCCCCCCEEECCCCCCCEEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
TPVALYSILTLVARQHGDFVD
CHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]