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The map label for this gene is yddA [H]

Identifier: 218548926

GI number: 218548926

Start: 1606431

End: 1608086

Strand: Direct

Name: yddA [H]

Synonym: EFER_1572

Alternate gene names: 218548926

Gene position: 1606431-1608086 (Clockwise)

Preceding gene: 218548923

Following gene: 218548927

Centisome position: 35.01

GC content: 42.33

Gene sequence:

>1656_bases
ATGTTAATAGCAAAATATCTTTGCCTACTGAAACCATTTTGGGTACGTAAAAACAATAAAACTTCAGTATTTTTGATCAT
CGTTATCCTCGCCATGATCCTTGGCGTTGTAAAAATTCAGGTGTGGTTGAATGACTGGAACAACGATTTTTTCAATGCTC
TAAGCCAAAAAGAGACTGATAAACTTTGGCAGCTGGTGTTATGGTTTCCGGTGCTTCTTGGTGTCTATGTATTAATATCC
GTAAACAAAACATGGCTTATTAAACTACTGACAATTCGTTGGCGCGAGTGGTTAACTGACTACTATCTTAAGCGCTGGTT
ACAGGACAAAAATTACTATTTCAGCCAACTCGACACTGAACATAAACATACCGATAACCCGGACCAACGTATTGCCGAAG
ACATCCTGCTTCTGATTAGCAAAACGTTAAGTCTTGCATTTGGCTTTATCCAGTCATTGAGCATGTTGGTCACTTTTACG
GTTATTCTTTGGCAAAGTGCCGGTACACTTTCGTTCTCCCTTGCAGGAGAAACGTGGCATATTCAGGGCTATATGGTGTA
CACCGTGGTGTTTATTGTTATTGGCGGAACACTTTTTACCCATAAAGTAGGCAAGCGTATTCGCCCGCTCAACGTTGAGA
AACAGCGTAGCGAAGCAAATTTCCGTGCCAACCTTGTGCAGCATAATAAGCAGGCAGAGCTAATTGCTCTGAGTAATGCA
GAACACCACCAGCAACAAGAGCTGTCTGATAATTTCACTACCATTAAGAAAAACTGGCACCAATTAATGAACCGCCAGCG
TTGGCTGGACTACTGGCAGAACGTCTACTCACGTTCACTGAGTGTACTGCCCTACTTTCTTCTGCTGCCACAATTCATTA
CCGGGCAGATCAATTTAGGCGGACTGATGAAATCACGCCAGGCTTTTATGCTGGTCTCGAATAACCTCAGTTGGTTTATC
TATAAATACGACGAACTTGCAGAACTGGCAGCTGTTATCGACCGTTTGTACGAATTTCATCAACTCACTGAACAACGCGT
GGTTAAAAAGCCGGATGTTAATGATCATAAGATTCAGGTAAAAGATGGCACTATTCATACCCCGGATAATCGACCATTGC
TGGAAAATCTCAACCTCAAGGTTGTTCCTGGCAAGTGGCTGTTGTTAAAAGGTATTTCTGGAGTTGGTAAAACAACGGTA
TTGAAAACGTTATCGCACTGCTGGCCGTGGTTTCAGGGTGATATTTCTTCCCCTGTTGATATTTGCTACGTACCGCAAGC
GCCATTAATTAAGTCTGGGAAGCTGAAAGATATTATTTGCAAAACGCTACCTGTCACTGTGGATGACAACGACATTAACA
ACGCCCTACATCTGGTAGGTTTAGTTAAATTAAAGGATCGATTAGAAGAGTTTGATCGCTGGGGAGATATTTTATCCAGT
GGAGAAAAACAACGAATCGCTTTAGCCAGAATTCTCTTACATCGTCCGAAATGGATATTTTTGGATGAAACAACCTCTCA
TCTGGAAGAACTGGAGGCAATCCGCTTATTACGTTTAGTACGCCAACAATTACCTGGAAGTGGTGTCATTATGGTTTCTC
ATCAGCCGGGATTGTGGTCTCTGGCAGACGATATTTGTGACATTAGCGCGGCTTAA

Upstream 100 bases:

>100_bases
TTAATAGTTAAAAAATTTTCAACTGTAAAATCTTGCAATAACTACTCACAAAGTGGCACAATCCGCGACGCTAATGATAA
TTGTTACCATTTAGGCTTGT

Downstream 100 bases:

>100_bases
TAATTATAACAAAAGCCCGCAGAGGAGATTTTTTTAATGAAACGAGTGCTTATTCCAGGCGTCATTTTATGTGGCGCCGA
TTTAGCCGTTGCCGCTGAGG

Product: multidrug ABC transporter permease/ATP-binding protein

Products: NA

Alternate protein names: CDS102 [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MLIAKYLCLLKPFWVRKNNKTSVFLIIVILAMILGVVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPVLLGVYVLIS
VNKTWLIKLLTIRWREWLTDYYLKRWLQDKNYYFSQLDTEHKHTDNPDQRIAEDILLLISKTLSLAFGFIQSLSMLVTFT
VILWQSAGTLSFSLAGETWHIQGYMVYTVVFIVIGGTLFTHKVGKRIRPLNVEKQRSEANFRANLVQHNKQAELIALSNA
EHHQQQELSDNFTTIKKNWHQLMNRQRWLDYWQNVYSRSLSVLPYFLLLPQFITGQINLGGLMKSRQAFMLVSNNLSWFI
YKYDELAELAAVIDRLYEFHQLTEQRVVKKPDVNDHKIQVKDGTIHTPDNRPLLENLNLKVVPGKWLLLKGISGVGKTTV
LKTLSHCWPWFQGDISSPVDICYVPQAPLIKSGKLKDIICKTLPVTVDDNDINNALHLVGLVKLKDRLEEFDRWGDILSS
GEKQRIALARILLHRPKWIFLDETTSHLEELEAIRLLRLVRQQLPGSGVIMVSHQPGLWSLADDICDISAA

Sequences:

>Translated_551_residues
MLIAKYLCLLKPFWVRKNNKTSVFLIIVILAMILGVVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPVLLGVYVLIS
VNKTWLIKLLTIRWREWLTDYYLKRWLQDKNYYFSQLDTEHKHTDNPDQRIAEDILLLISKTLSLAFGFIQSLSMLVTFT
VILWQSAGTLSFSLAGETWHIQGYMVYTVVFIVIGGTLFTHKVGKRIRPLNVEKQRSEANFRANLVQHNKQAELIALSNA
EHHQQQELSDNFTTIKKNWHQLMNRQRWLDYWQNVYSRSLSVLPYFLLLPQFITGQINLGGLMKSRQAFMLVSNNLSWFI
YKYDELAELAAVIDRLYEFHQLTEQRVVKKPDVNDHKIQVKDGTIHTPDNRPLLENLNLKVVPGKWLLLKGISGVGKTTV
LKTLSHCWPWFQGDISSPVDICYVPQAPLIKSGKLKDIICKTLPVTVDDNDINNALHLVGLVKLKDRLEEFDRWGDILSS
GEKQRIALARILLHRPKWIFLDETTSHLEELEAIRLLRLVRQQLPGSGVIMVSHQPGLWSLADDICDISAA
>Mature_551_residues
MLIAKYLCLLKPFWVRKNNKTSVFLIIVILAMILGVVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPVLLGVYVLIS
VNKTWLIKLLTIRWREWLTDYYLKRWLQDKNYYFSQLDTEHKHTDNPDQRIAEDILLLISKTLSLAFGFIQSLSMLVTFT
VILWQSAGTLSFSLAGETWHIQGYMVYTVVFIVIGGTLFTHKVGKRIRPLNVEKQRSEANFRANLVQHNKQAELIALSNA
EHHQQQELSDNFTTIKKNWHQLMNRQRWLDYWQNVYSRSLSVLPYFLLLPQFITGQINLGGLMKSRQAFMLVSNNLSWFI
YKYDELAELAAVIDRLYEFHQLTEQRVVKKPDVNDHKIQVKDGTIHTPDNRPLLENLNLKVVPGKWLLLKGISGVGKTTV
LKTLSHCWPWFQGDISSPVDICYVPQAPLIKSGKLKDIICKTLPVTVDDNDINNALHLVGLVKLKDRLEEFDRWGDILSS
GEKQRIALARILLHRPKWIFLDETTSHLEELEAIRLLRLVRQQLPGSGVIMVSHQPGLWSLADDICDISAA

Specific function: Unknown

COG id: COG4178

COG function: function code R; ABC-type uncharacterized transport system, permease and ATPase components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI4826958, Length=537, Percent_Identity=25.6983240223464, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI9945308, Length=517, Percent_Identity=24.9516441005803, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI7262393, Length=554, Percent_Identity=23.2851985559567, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI4506341, Length=590, Percent_Identity=21.1864406779661, Blast_Score=108, Evalue=2e-23,
Organism=Escherichia coli, GI1787772, Length=550, Percent_Identity=83.2727272727273, Blast_Score=927, Evalue=0.0,
Organism=Escherichia coli, GI1786575, Length=321, Percent_Identity=25.2336448598131, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787112, Length=267, Percent_Identity=27.3408239700375, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17532411, Length=600, Percent_Identity=25.1666666666667, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17542146, Length=556, Percent_Identity=23.021582733813, Blast_Score=118, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17532409, Length=508, Percent_Identity=24.0157480314961, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI72000520, Length=539, Percent_Identity=25.2319109461967, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17564250, Length=555, Percent_Identity=25.4054054054054, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI25146777, Length=230, Percent_Identity=30.4347826086957, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17511077, Length=220, Percent_Identity=26.8181818181818, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17533971, Length=326, Percent_Identity=24.5398773006135, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17558664, Length=159, Percent_Identity=32.7044025157233, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71988343, Length=564, Percent_Identity=21.6312056737589, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558960, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324985, Length=266, Percent_Identity=29.6992481203008, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6325110, Length=145, Percent_Identity=31.7241379310345, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323217, Length=254, Percent_Identity=28.740157480315, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322980, Length=264, Percent_Identity=24.2424242424242, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24638550, Length=556, Percent_Identity=22.6618705035971, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638552, Length=556, Percent_Identity=22.6618705035971, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638554, Length=556, Percent_Identity=22.6618705035971, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638546, Length=556, Percent_Identity=22.6618705035971, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638556, Length=556, Percent_Identity=22.6618705035971, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638548, Length=556, Percent_Identity=22.6618705035971, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24643394, Length=535, Percent_Identity=24.2990654205607, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24638558, Length=525, Percent_Identity=22.4761904761905, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010509
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF06472 ABC_membrane_2; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 63919; Mature: 63919

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIAKYLCLLKPFWVRKNNKTSVFLIIVILAMILGVVKIQVWLNDWNNDFFNALSQKETD
CHHHHHHHHHCHHHEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHH
KLWQLVLWFPVLLGVYVLISVNKTWLIKLLTIRWREWLTDYYLKRWLQDKNYYFSQLDTE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
HKHTDNPDQRIAEDILLLISKTLSLAFGFIQSLSMLVTFTVILWQSAGTLSFSLAGETWH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEE
IQGYMVYTVVFIVIGGTLFTHKVGKRIRPLNVEKQRSEANFRANLVQHNKQAELIALSNA
ECHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCC
EHHQQQELSDNFTTIKKNWHQLMNRQRWLDYWQNVYSRSLSVLPYFLLLPQFITGQINLG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLMKSRQAFMLVSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRVVKKPDVNDHKIQV
HHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
KDGTIHTPDNRPLLENLNLKVVPGKWLLLKGISGVGKTTVLKTLSHCWPWFQGDISSPVD
ECCEEECCCCCCHHHCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
ICYVPQAPLIKSGKLKDIICKTLPVTVDDNDINNALHLVGLVKLKDRLEEFDRWGDILSS
EEECCCCCCCCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEKQRIALARILLHRPKWIFLDETTSHLEELEAIRLLRLVRQQLPGSGVIMVSHQPGLWS
CCHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHH
LADDICDISAA
HHHHHHCCCCC
>Mature Secondary Structure
MLIAKYLCLLKPFWVRKNNKTSVFLIIVILAMILGVVKIQVWLNDWNNDFFNALSQKETD
CHHHHHHHHHCHHHEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHH
KLWQLVLWFPVLLGVYVLISVNKTWLIKLLTIRWREWLTDYYLKRWLQDKNYYFSQLDTE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
HKHTDNPDQRIAEDILLLISKTLSLAFGFIQSLSMLVTFTVILWQSAGTLSFSLAGETWH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEE
IQGYMVYTVVFIVIGGTLFTHKVGKRIRPLNVEKQRSEANFRANLVQHNKQAELIALSNA
ECHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCC
EHHQQQELSDNFTTIKKNWHQLMNRQRWLDYWQNVYSRSLSVLPYFLLLPQFITGQINLG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLMKSRQAFMLVSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRVVKKPDVNDHKIQV
HHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
KDGTIHTPDNRPLLENLNLKVVPGKWLLLKGISGVGKTTVLKTLSHCWPWFQGDISSPVD
ECCEEECCCCCCHHHCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
ICYVPQAPLIKSGKLKDIICKTLPVTVDDNDINNALHLVGLVKLKDRLEEFDRWGDILSS
EEECCCCCCCCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEKQRIALARILLHRPKWIFLDETTSHLEELEAIRLLRLVRQQLPGSGVIMVSHQPGLWS
CCHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHH
LADDICDISAA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]