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The map label for this gene is ydhM [H]

Identifier: 218548756

GI number: 218548756

Start: 1435289

End: 1435804

Strand: Reverse

Name: ydhM [H]

Synonym: EFER_1395

Alternate gene names: 218548756

Gene position: 1435804-1435289 (Counterclockwise)

Preceding gene: 218548759

Following gene: 218548755

Centisome position: 31.29

GC content: 52.13

Gene sequence:

>516_bases
ATGGGGCTAAGCGAATTACTAAAAACTGCTGAAGTGCCGAAAGGGTCCTTCTATCACTACTTTCGCTCTAAAGAAGCGTT
TGGCGTTGCCATGCTTGAGCGCCATTACGCCGCATATCACCTGCGACTGACTGAGTTGCTGCAATCCGGCGAAGGTAACT
ACCGCGACCGCATACTGGCTTATTACCAGCAAACACTGAACCAGTTTTGCCAACATGGAACCATCAGTGGTTGCCTGACA
GTAAAACTCTCTGCCGAAGTGTGCGATCTGTCAGAAGATATGCGCAGCGCGATGGATAAAGGGGCTCGCGGCGTGATCGC
CCTGCTCTCTCAGGCGCTGGAAAATGGCCGTGAGAACCATTGTTTAACCTTTTGTGGCGAACCGCTGCAACAGGCACAAG
TGCTTTACGCACTGTGGCTTGGCGCGAATTTGCAGGCCAAAATTTCGCGCAGTTTCGAGCCACTGGAAAACGCGCTGGCC
CATGTAAAAACCATTATTGCGACGCCTGCCGTTTAG

Upstream 100 bases:

>100_bases
TACTACACTCCAACACATGAACAAACACACCGAACATGATACTCGCGAACATCTCCTGGCGACGGGCGAACAACTTTGCC
TGCAACGTGGATTCACCGGG

Downstream 100 bases:

>100_bases
CAGGCATTTTTTATCACCAGACCACCGGGAGCCTTTATGTCATCTGAAAAACTGTATTCCCCACTGAAAGTGGGCGCGAT
CACGGCGGCAAACCGTATTT

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHLRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLT
VKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALA
HVKTIIATPAV

Sequences:

>Translated_171_residues
MGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHLRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLT
VKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALA
HVKTIIATPAV
>Mature_170_residues
GLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHLRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLTV
KLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALAH
VKTIIATPAV

Specific function: Represses the transcription of the nemRA operon by binding to the nemR box [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=171, Percent_Identity=98.8304093567251, Blast_Score=350, Evalue=2e-98,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 19042; Mature: 18911

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHLRLTELLQSGEGNYRDRILA
CCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YYQQTLNQFCQHGTISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENH
HHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
CLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALAHVKTIIATPAV
EEEECCCHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHLRLTELLQSGEGNYRDRILA
CHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YYQQTLNQFCQHGTISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENH
HHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
CLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALAHVKTIIATPAV
EEEECCCHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]