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The map label for this gene is potC [H]

Identifier: 218548654

GI number: 218548654

Start: 1327234

End: 1328028

Strand: Reverse

Name: potC [H]

Synonym: EFER_1288

Alternate gene names: 218548654

Gene position: 1328028-1327234 (Counterclockwise)

Preceding gene: 218548655

Following gene: 218548653

Centisome position: 28.94

GC content: 49.18

Gene sequence:

>795_bases
ATGATCGGTCGACTGCTTCGCGGCGGTTTTATGACCGCTATCTACGCGTATCTGTATATTCCAATCATTATTTTGATTGT
GAATTCCTTTAACAGCTCGCGCTTTGGCATCAACTGGCAGGGTTTTACCACCAAATGGTATAGCCTGCTGATGAACAACG
ACAGTCTGTTACAGGCAGCGCAGCATTCACTGACGATGGCGGTGTTTTCGGCGACGTTTGCTACGCTTATCGGTTCACTG
ACGGCAGTTGCGCTGTACCGTTATCGCTTTCGTGGTAAGCCGTTCGTTAGTGGAATGCTGTTTGTAGTGATGATGTCGCC
AGATATCGTAATGGCTATTTCTCTGCTGGTGCTGTTTATGCTGCTTGGTATTCAGCTTGGCTTCTGGTCGCTGCTGTTCT
CGCACATCACCTTTTGCCTGCCATTTGTGGTGGTGACGGTGTATTCGCGTCTGAAAGGTTTTGATGTGCGAATGCTGGAA
GCGGCGAAAGATCTCGGTGCCAGCGAATTTACCATTCTGCGAAAAATCATTCTGCCACTGGCAATGCCAGCGGTAGCGGC
GGGCTGGGTGTTAAGCTTTACCCTGTCGATGGACGACGTGGTAGTTTCTTCGTTCGTCACCGGACCAGGCTATGAAATTC
TGCCGTTAAAAATTTATTCGATGGTCAAAGTCGGCGTATCGCCGGAAGTTAACGCGCTGGCAACCATATTACTGGTGCTG
TCGCTGGTGATGGTTATTGCCAGCCAGCTTATTGCTCGTGATAAAACGAAAGGTAACACAGGGGACGTTAAATGA

Upstream 100 bases:

>100_bases
TTGGTGCAGCCACCAGCATTACGCTGACTATCGTAATGGGCCTGATGTTGCTGGTTTACTGGCGCGCTTCTCGTTTGCTG
AATAAGAAGGTGGAACTCGA

Downstream 100 bases:

>100_bases
AAAAATGGTCACGCCACCTGCTCGCGGCGGGTGCTCTGGCACTGGGCATGAGCGCCGCTCACGCCGATGACAACAACACG
CTGTATTTCTACAACTGGAC

Product: spermidine/putrescine ABC transporter membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTTKWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSL
TAVALYRYRFRGKPFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPGYEILPLKIYSMVKVGVSPEVNALATILLVL
SLVMVIASQLIARDKTKGNTGDVK

Sequences:

>Translated_264_residues
MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTTKWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSL
TAVALYRYRFRGKPFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPGYEILPLKIYSMVKVGVSPEVNALATILLVL
SLVMVIASQLIARDKTKGNTGDVK
>Mature_264_residues
MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTTKWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSL
TAVALYRYRFRGKPFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPGYEILPLKIYSMVKVGVSPEVNALATILLVL
SLVMVIASQLIARDKTKGNTGDVK

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=264, Percent_Identity=99.6212121212121, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1787081, Length=251, Percent_Identity=40.6374501992032, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1787714, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788764, Length=207, Percent_Identity=28.0193236714976, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787713, Length=116, Percent_Identity=31.8965517241379, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29081; Mature: 29081

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]