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The map label for this gene is ycbL [H]

Identifier: 218548443

GI number: 218548443

Start: 1111138

End: 1111785

Strand: Direct

Name: ycbL [H]

Synonym: EFER_1071

Alternate gene names: 218548443

Gene position: 1111138-1111785 (Clockwise)

Preceding gene: 218548442

Following gene: 218548448

Centisome position: 24.21

GC content: 51.7

Gene sequence:

>648_bases
ATGAACTATCGTATTATTCCGGTCACCGCATTCTCCCAGAACTGTTCATTGATCTGGTGTGAACAAACCCGTCTGGCCGC
ACTGGTCGATCCTGGCGGCGATGCGGAAAAAATCAAACAGGAAGTTGACGCCAGCGGCCTGACGCTGATGCAGATCCTGC
TGACGCATGGTCATCTGGACCATGTTGGTGCAGCGGCGGAACTGGCGCAACATTACGGCGTGCCGGTTCTTGGCCCGGAA
AAAGAAGATGAGTTTTGGCTGCAAGGTTTGCCAGCGCAAAGTCGTATGTTTGGACTGGACGAGTGTCAGCCATTGACGCC
GGATCGTTGGCTCAATGATGGCGATACCATCAGCATAGGGAATGTGACTTTACAGGTGTTACATTGCCCTGGGCATACGC
CGGGTCATGTGGTGTTTTTTGATGATCAGGCAAAGCTGCTGATTTCTGGCGATGTTATTTTCAAAGGCGGAGTAGGGCGT
AGTGACTTCCCGCGTGGCGATCACAATCAACTGATTGCTGCAATCAAAGATAAATTGCTGCCGCTGGGTGATGACGTGAC
ATTTATTCCGGGTCACGGACCATTATCCACTCTTGGTTACGAGCGGTTGCATAACCCCTTCCTGCAAGATGAAATGCCCG
TCTGGTAA

Upstream 100 bases:

>100_bases
GCGCAGGTGGTGTAGGATATTACCCACGTAGTAACTTTGTGCATATTGATACCGGGCCAGCACGGCACTGGTAGCAATCG
CTTAACAAAACAGGGGCAGT

Downstream 100 bases:

>100_bases
GGCACATAAAAAAGCCCGCTTTCACAGCGGGCTTCGTTTAACTAGTCTTTACAGCACTGCCACAATCGCTTCGCAAAGCG
GCGCCATGTTATCTGGCGTC

Product: metal-binding hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLDHVGAAAELAQHYGVPVLGPE
KEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDTISIGNVTLQVLHCPGHTPGHVVFFDDQAKLLISGDVIFKGGVGR
SDFPRGDHNQLIAAIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW

Sequences:

>Translated_215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLDHVGAAAELAQHYGVPVLGPE
KEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDTISIGNVTLQVLHCPGHTPGHVVFFDDQAKLLISGDVIFKGGVGR
SDFPRGDHNQLIAAIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
>Mature_215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLDHVGAAAELAQHYGVPVLGPE
KEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDTISIGNVTLQVLHCPGHTPGHVVFFDDQAKLLISGDVIFKGGVGR
SDFPRGDHNQLIAAIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI21703352, Length=196, Percent_Identity=31.6326530612245, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI116642887, Length=196, Percent_Identity=31.6326530612245, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI41327741, Length=203, Percent_Identity=29.064039408867, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787158, Length=215, Percent_Identity=96.2790697674419, Blast_Score=429, Evalue=1e-122,
Organism=Drosophila melanogaster, GI21356335, Length=213, Percent_Identity=29.5774647887324, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24667703, Length=213, Percent_Identity=29.5774647887324, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24667711, Length=213, Percent_Identity=29.5774647887324, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23606; Mature: 23606

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLD
CCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCHH
HVGAAAELAQHYGVPVLGPEKEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDTISIG
HHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCHHCCCCCCEEEEC
NVTLQVLHCPGHTPGHVVFFDDQAKLLISGDVIFKGGVGRSDFPRGDHNQLIAAIKDKLL
CEEEEEEECCCCCCCEEEEECCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHCC
PLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
CCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLD
CCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCHH
HVGAAAELAQHYGVPVLGPEKEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDTISIG
HHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCHHCCCCCCEEEEC
NVTLQVLHCPGHTPGHVVFFDDQAKLLISGDVIFKGGVGRSDFPRGDHNQLIAAIKDKLL
CEEEEEEECCCCCCCEEEEECCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHCC
PLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
CCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]