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The map label for this gene is ompC [H]

Identifier: 218548324

GI number: 218548324

Start: 972532

End: 973653

Strand: Direct

Name: ompC [H]

Synonym: EFER_0945

Alternate gene names: 218548324

Gene position: 972532-973653 (Clockwise)

Preceding gene: 218548321

Following gene: 218548325

Centisome position: 21.19

GC content: 48.75

Gene sequence:

>1122_bases
ATGAAAGTTAAAGTACTGTCCCTCCTGGTACCGGCTCTGCTGGTAGCAGGCGCAGCAAATGCGGCTGAAATTTACAACAA
AGACGGCAACAAATTAGATCTGTACGGCAAAGTAGATGGTCTGCACTATTTCTCTGACGACAAGTCTGTAGATGGTGACA
AAACCTACATGCGTATCGGCTTCAAAGGCGAAACTCAGGTTACTGATCAACTGACAGGTTATGGTCAGTGGGAATATCAG
ATCCAGGGCAATGCTCCGGAAAGCGAAAACAACTCCTGGACCCGTGTAGCATTCGCTGGTCTGAAATTCCAGGACGTTGG
CTCTTTCGACTATGGTCGTAACTACGGTGTTGTTTATGACGTAACATCCTGGACCGACGTGCTGCCAGAATTCGGTGGTG
ACACCTACAGCTCTGACAACTTCATGCAGCAGCGTGGTAACGGCTTCGCGACCTACCGTAACACTGACTTCTTCGGTCTG
GTTGATGGCCTGAACTTTGCTATTCAGTACCAGGGTAAAAACGGTAGCCCGTCTGGCGAAGGTATGACTGGTGTGACCAA
CAATGGTCGTGATGCTCTGGAGCAGAACGGTGACGGCGTTGGTGGTTCTATCACTTATGACATCGGTGAAGGCTTCAGCT
TCGGTGGTGCGATCTCCAGCTCCAAACGTACCGCAGAGCAGAACAACAGTGTTCGTTACATCGGTAACGGCGATCGTGCA
GAAACCTACACTGGTGGTCTGAAATACGACGCTAACAATGTATACCTGGCTGCTCAGTACACCCAGACTTACAACGCAAC
TCTGGCTGGTGATTTAGGTTGGGCGAACAAAGCTCAGAACTTTGAAGTGGTTGCCCAGTACCAGTTCGACTTCGGTCTGC
GTCCTTCTGTAGCTTACCTGCAGTCCAAAGGTAAAAACCTGAATGCCAACATCGCTGGTCGTACTTACGACGACGAAGAT
TTGCTGAAATATGTTGATGTTGGTGCTACTTACTACTTCAACAAAAACATGTCCACCTATGTTGATTACAAAATCAACCT
GCTGGACGACAATAACTTCACCCGCGCTGCTGGCATCAACACTGATGACATCGTAGCTCTGGGTCTGGTTTATCAGTTCT
AA

Upstream 100 bases:

>100_bases
AATTTTAAGGAGAATGAAGTTGCCGGCTGATTAATGAGGGTTAATCAGTAAGCAGTGGCATAAAAAGCAAATAAAAGGCA
TATAACAGAGGGTTATTAAC

Downstream 100 bases:

>100_bases
TCTCGATTTCTGTTGACCAAAGGGCCTGCGGGCCCTTTTTTCATTGCTTTTTCATACTCTTCAACGCACAAATGCTGATT
TTTGGTGTACTCTTGCGCCC

Product: outer membrane porin protein C

Products: NA

Alternate protein names: Outer membrane protein 1B; Porin ompC [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDDKSVDGDKTYMRIGFKGETQVTDQLTGYGQWEYQ
IQGNAPESENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYSSDNFMQQRGNGFATYRNTDFFGL
VDGLNFAIQYQGKNGSPSGEGMTGVTNNGRDALEQNGDGVGGSITYDIGEGFSFGGAISSSKRTAEQNNSVRYIGNGDRA
ETYTGGLKYDANNVYLAAQYTQTYNATLAGDLGWANKAQNFEVVAQYQFDFGLRPSVAYLQSKGKNLNANIAGRTYDDED
LLKYVDVGATYYFNKNMSTYVDYKINLLDDNNFTRAAGINTDDIVALGLVYQF

Sequences:

>Translated_373_residues
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDDKSVDGDKTYMRIGFKGETQVTDQLTGYGQWEYQ
IQGNAPESENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYSSDNFMQQRGNGFATYRNTDFFGL
VDGLNFAIQYQGKNGSPSGEGMTGVTNNGRDALEQNGDGVGGSITYDIGEGFSFGGAISSSKRTAEQNNSVRYIGNGDRA
ETYTGGLKYDANNVYLAAQYTQTYNATLAGDLGWANKAQNFEVVAQYQFDFGLRPSVAYLQSKGKNLNANIAGRTYDDED
LLKYVDVGATYYFNKNMSTYVDYKINLLDDNNFTRAAGINTDDIVALGLVYQF
>Mature_373_residues
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDDKSVDGDKTYMRIGFKGETQVTDQLTGYGQWEYQ
IQGNAPESENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYSSDNFMQQRGNGFATYRNTDFFGL
VDGLNFAIQYQGKNGSPSGEGMTGVTNNGRDALEQNGDGVGGSITYDIGEGFSFGGAISSSKRTAEQNNSVRYIGNGDRA
ETYTGGLKYDANNVYLAAQYTQTYNATLAGDLGWANKAQNFEVVAQYQFDFGLRPSVAYLQSKGKNLNANIAGRTYDDED
LLKYVDVGATYYFNKNMSTYVDYKINLLDDNNFTRAAGINTDDIVALGLVYQF

Specific function: Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane [H]

COG id: COG3203

COG function: function code M; Outer membrane protein (porin)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

Organism=Escherichia coli, GI1788544, Length=374, Percent_Identity=89.3048128342246, Blast_Score=656, Evalue=0.0,
Organism=Escherichia coli, GI1787641, Length=383, Percent_Identity=68.1462140992167, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1786436, Length=377, Percent_Identity=57.0291777188329, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1787160, Length=386, Percent_Identity=56.7357512953368, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: 6020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 19068 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001897
- InterPro:   IPR013793
- InterPro:   IPR001702 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 40951; Mature: 40951

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00576 GRAM_NEG_PORIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDDKSVDGDKTYMRIG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEE
FKGETQVTDQLTGYGQWEYQIQGNAPESENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYD
CCCCCEEHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECEEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYSSDNFMQQRGNGFATYRNTDFFGLVDGLNFAIQYQGKNGSPSGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCCC
GMTGVTNNGRDALEQNGDGVGGSITYDIGEGFSFGGAISSSKRTAEQNNSVRYIGNGDRA
CCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCC
ETYTGGLKYDANNVYLAAQYTQTYNATLAGDLGWANKAQNFEVVAQYQFDFGLRPSVAYL
CEEECCEEECCCCEEEEEEECEEECEEEECCCCCCCCCCCEEEEEEEEECCCCCCCHHHH
QSKGKNLNANIAGRTYDDEDLLKYVDVGATYYFNKNMSTYVDYKINLLDDNNFTRAAGIN
HHCCCCCCEEECCCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEEECCCEEEECCCC
TDDIVALGLVYQF
CCCEEEEEEEECC
>Mature Secondary Structure
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDDKSVDGDKTYMRIG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEE
FKGETQVTDQLTGYGQWEYQIQGNAPESENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYD
CCCCCEEHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECEEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYSSDNFMQQRGNGFATYRNTDFFGLVDGLNFAIQYQGKNGSPSGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCCC
GMTGVTNNGRDALEQNGDGVGGSITYDIGEGFSFGGAISSSKRTAEQNNSVRYIGNGDRA
CCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCC
ETYTGGLKYDANNVYLAAQYTQTYNATLAGDLGWANKAQNFEVVAQYQFDFGLRPSVAYL
CEEECCEEECCCCEEEEEEECEEECEEEECCCCCCCCCCCEEEEEEEEECCCCCCCHHHH
QSKGKNLNANIAGRTYDDEDLLKYVDVGATYYFNKNMSTYVDYKINLLDDNNFTRAAGIN
HHCCCCCCEEECCCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEEECCCEEEECCCC
TDDIVALGLVYQF
CCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]