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The map label for this gene is lrhA [H]

Identifier: 218548262

GI number: 218548262

Start: 894966

End: 895904

Strand: Direct

Name: lrhA [H]

Synonym: EFER_0881

Alternate gene names: 218548262

Gene position: 894966-895904 (Clockwise)

Preceding gene: 218548259

Following gene: 218548263

Centisome position: 19.5

GC content: 47.82

Gene sequence:

>939_bases
ATGATAAACGCAAATCGTCCGATAATTAACCTCGACCTCGATCTGCTGAGAACATTTGTTGCTGTTGCCGATCTGAATAC
GTTTGCAGCGGCAGCAGCTGCGGTTTGTCGTACTCAGTCCGCAGTCAGTCAGCAAATGCAGCGCCTGGAGCAACTCGTAG
GTAAAGAACTGTTCGCTCGCCACGGGCGTAATAAATTGTTGACGGAACATGGCATTCAGCTTCTTGGCTATGCCAGGAAA
ATATTGCGATTCAATGATGAGGCATGCTCATCATTAATGTTCAGCAATCTTCAGGGGGTATTAACTATCGGTGCTTCCGA
TGAATCAGCCGATACAATTCTTCCTTTTCTATTAAACAGGATTAGTTCGGTTTATCCGAAGCTTGCACTGGATGTCCGGG
TAAAACGCAATGCATTTATGGCTGAGATGTTAAAATCTCAGGAAGTTGATCTCATTGTGACTACACACCGTCCAGAGACA
GGCAACGCCCTTAATTTGCGTACATCTCCGACGCACTGGTATTGTGCAGCGGAATATGTTTTGCAGCGTGGAGAGCCAGT
GCCGCTGGTATTATTAGATGAGCCCAGCCCGTTTCGTGATATGGTCCTTGAGACTTTGAATGCGGCTGATATTCCCTGGC
GTCTGGCTTATGTTGCTTCAACGTTGCCAGCTGTTCGTGCAGCAGTAAAAGCGGGTTTAGGTGTAACAGCGCGTCCGGTT
GAGATGATGAGCCCGGATCTTCGTGTCCTTGGCGCTGTGGATGGTTTGCCAATGCTGCCAGATACCGAATATCTGTTGTG
CTGTGATCCAGAAGGTAAAAACGAACTGGCGCAAATCATCTATCAGGCGATGGAGAGTTATCAAAATCCCTGGCAATACG
GCAATGTTACCGTTGAGGGTGGAGACGATCCGCTTCTGATTGAAAGCGATTTTCGCTAA

Upstream 100 bases:

>100_bases
TGAATCTGCCAGGGTGGCACATTACAAATGGAATTGTTTGCTTGTTTGTGTGTGCACAGCATTAACCAGCTCAGAATGAG
CCGCCAGTAAGTGAAAAATT

Downstream 100 bases:

>100_bases
AAGTTGTTTTAAGCATTAAAAAATCTGAATAAAAAATAGCCACTGACGTGTGAAAGCACTCAGGGGCTATTTTTTTGTAC
TACTATCAATGTCAGTTTCA

Product: flagellar, motility and chemotaxis genes DNA-binding transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLNRISSVYPKLALDVRVKRNAFMAEMLKSQEVDLIVTTHRPET
GNALNLRTSPTHWYCAAEYVLQRGEPVPLVLLDEPSPFRDMVLETLNAADIPWRLAYVASTLPAVRAAVKAGLGVTARPV
EMMSPDLRVLGAVDGLPMLPDTEYLLCCDPEGKNELAQIIYQAMESYQNPWQYGNVTVEGGDDPLLIESDFR

Sequences:

>Translated_312_residues
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLNRISSVYPKLALDVRVKRNAFMAEMLKSQEVDLIVTTHRPET
GNALNLRTSPTHWYCAAEYVLQRGEPVPLVLLDEPSPFRDMVLETLNAADIPWRLAYVASTLPAVRAAVKAGLGVTARPV
EMMSPDLRVLGAVDGLPMLPDTEYLLCCDPEGKNELAQIIYQAMESYQNPWQYGNVTVEGGDDPLLIESDFR
>Mature_312_residues
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLNRISSVYPKLALDVRVKRNAFMAEMLKSQEVDLIVTTHRPET
GNALNLRTSPTHWYCAAEYVLQRGEPVPLVLLDEPSPFRDMVLETLNAADIPWRLAYVASTLPAVRAAVKAGLGVTARPV
EMMSPDLRVLGAVDGLPMLPDTEYLLCCDPEGKNELAQIIYQAMESYQNPWQYGNVTVEGGDDPLLIESDFR

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=311, Percent_Identity=89.0675241157556, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI48994962, Length=152, Percent_Identity=30.2631578947368, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787806, Length=130, Percent_Identity=30, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693105, Length=243, Percent_Identity=23.4567901234568, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34531; Mature: 34531

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLNR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
ISSVYPKLALDVRVKRNAFMAEMLKSQEVDLIVTTHRPETGNALNLRTSPTHWYCAAEYV
HHHHCCHHEEEEEEHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHH
LQRGEPVPLVLLDEPSPFRDMVLETLNAADIPWRLAYVASTLPAVRAAVKAGLGVTARPV
HHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVLGAVDGLPMLPDTEYLLCCDPEGKNELAQIIYQAMESYQNPWQYGNVTVEG
HHCCCCHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEC
GDDPLLIESDFR
CCCCEEEECCCC
>Mature Secondary Structure
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLNR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
ISSVYPKLALDVRVKRNAFMAEMLKSQEVDLIVTTHRPETGNALNLRTSPTHWYCAAEYV
HHHHCCHHEEEEEEHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHH
LQRGEPVPLVLLDEPSPFRDMVLETLNAADIPWRLAYVASTLPAVRAAVKAGLGVTARPV
HHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVLGAVDGLPMLPDTEYLLCCDPEGKNELAQIIYQAMESYQNPWQYGNVTVEG
HHCCCCHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEC
GDDPLLIESDFR
CCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]