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The map label for this gene is yfbT [H]

Identifier: 218548258

GI number: 218548258

Start: 889522

End: 890172

Strand: Direct

Name: yfbT [H]

Synonym: EFER_0876

Alternate gene names: 218548258

Gene position: 889522-890172 (Clockwise)

Preceding gene: 218548257

Following gene: 218548259

Centisome position: 19.39

GC content: 51.46

Gene sequence:

>651_bases
GTGCGGTGTAAAGGCTTTCTGTTTGACCTTGATGGTACGCTGGTTGATTCCTTACCGGCAGTAGAGCGTGCGTGGTGTAA
CTGGGCCGATCGTTTTGGGATTGATCACCATGAGTTGTTGAGTTTCATTCATGGCAAACAGGCGATCACTTCTCTGCGCC
ATTTTATGCCAGGAAGACCGGAGGAAGAGATACTGGCTGAATTTACCCGCCTGGAGCAGATCGAGGCGACGCAAACTGAA
GGTATCACCGCACTACCAGGGGCGATTGAACTCCTCACTCATCTTAATAAATCAGGCATTCCATGGGCTATCGTTACTTC
TGGCTCAATGCCGGTTGCACGTGCTCGCCATCAGGTTGCCGGGCTGCCATTCCCTGAAGTATTTGTTACCGCTGAACGGG
TAAAAAGAGGGAAACCAGAACCGGATGCTTATCTCTTGGGGGCGCAACTGCTCGGCCTTGAACCAAAAGAGTGTGTTGTC
GTGGAGGATGCCCCTGCGGGTGTACTTTCCGGGTTGGCTGCAGGTTGCCATGTCATTGCTGTGAATACGCCAGCAGACAC
GCCGCGTTTGAGTGAGGTTGATTTTGTGCTGACCAGTTTGCAGCAAATCACCGTAACAAAGCAGCCGAATGGAGAAGTTA
TTATTCAGTGA

Upstream 100 bases:

>100_bases
AAGTACCAGCGAATGTTAAAAGTTTGGCATTCTTGCCCGCGTCAATACCACTTGAGCGCTAACGAAATTAATCAAATTAT
CAACGCCTGAGGAGGCTGAT

Downstream 100 bases:

>100_bases
AACACCTGAGTATGATTTAGCTCCGTTTTGGTGGTTTTGTTTTATGGCAGAATCTAGTAATTCTCATCATTTAACAAGGA
TGTATTGTGAACGGTGAATT

Product: phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MRCKGFLFDLDGTLVDSLPAVERAWCNWADRFGIDHHELLSFIHGKQAITSLRHFMPGRPEEEILAEFTRLEQIEATQTE
GITALPGAIELLTHLNKSGIPWAIVTSGSMPVARARHQVAGLPFPEVFVTAERVKRGKPEPDAYLLGAQLLGLEPKECVV
VEDAPAGVLSGLAAGCHVIAVNTPADTPRLSEVDFVLTSLQQITVTKQPNGEVIIQ

Sequences:

>Translated_216_residues
MRCKGFLFDLDGTLVDSLPAVERAWCNWADRFGIDHHELLSFIHGKQAITSLRHFMPGRPEEEILAEFTRLEQIEATQTE
GITALPGAIELLTHLNKSGIPWAIVTSGSMPVARARHQVAGLPFPEVFVTAERVKRGKPEPDAYLLGAQLLGLEPKECVV
VEDAPAGVLSGLAAGCHVIAVNTPADTPRLSEVDFVLTSLQQITVTKQPNGEVIIQ
>Mature_216_residues
MRCKGFLFDLDGTLVDSLPAVERAWCNWADRFGIDHHELLSFIHGKQAITSLRHFMPGRPEEEILAEFTRLEQIEATQTE
GITALPGAIELLTHLNKSGIPWAIVTSGSMPVARARHQVAGLPFPEVFVTAERVKRGKPEPDAYLLGAQLLGLEPKECVV
VEDAPAGVLSGLAAGCHVIAVNTPADTPRLSEVDFVLTSLQQITVTKQPNGEVIIQ

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrate glucose 6-phosphate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=216, Percent_Identity=31.4814814814815, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI207113149, Length=193, Percent_Identity=31.6062176165803, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI87082080, Length=216, Percent_Identity=85.6481481481482, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1789046, Length=195, Percent_Identity=29.2307692307692, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790151, Length=221, Percent_Identity=28.5067873303167, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321834, Length=229, Percent_Identity=32.7510917030568, Blast_Score=111, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6321833, Length=229, Percent_Identity=31.4410480349345, Blast_Score=104, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6322136, Length=219, Percent_Identity=32.8767123287671, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320905, Length=219, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=5e-19,
Organism=Drosophila melanogaster, GI20129151, Length=191, Percent_Identity=30.8900523560209, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 23505; Mature: 23505

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCKGFLFDLDGTLVDSLPAVERAWCNWADRFGIDHHELLSFIHGKQAITSLRHFMPGRP
CCCCCEEEECCCHHHHHCHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
EEEILAEFTRLEQIEATQTEGITALPGAIELLTHLNKSGIPWAIVTSGSMPVARARHQVA
HHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHC
GLPFPEVFVTAERVKRGKPEPDAYLLGAQLLGLEPKECVVVEDAPAGVLSGLAAGCHVIA
CCCCHHHHHHHHHHHCCCCCCCCEEECHHHHCCCCCCEEEECCCCHHHHHHHHCCCEEEE
VNTPADTPRLSEVDFVLTSLQQITVTKQPNGEVIIQ
EECCCCCCCCHHHHHHHHHHHHEEEEECCCCCEEEC
>Mature Secondary Structure
MRCKGFLFDLDGTLVDSLPAVERAWCNWADRFGIDHHELLSFIHGKQAITSLRHFMPGRP
CCCCCEEEECCCHHHHHCHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
EEEILAEFTRLEQIEATQTEGITALPGAIELLTHLNKSGIPWAIVTSGSMPVARARHQVA
HHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHC
GLPFPEVFVTAERVKRGKPEPDAYLLGAQLLGLEPKECVVVEDAPAGVLSGLAAGCHVIA
CCCCHHHHHHHHHHHCCCCCCCCEEECHHHHCCCCCCEEEECCCCHHHHHHHHCCCEEEE
VNTPADTPRLSEVDFVLTSLQQITVTKQPNGEVIIQ
EECCCCCCCCHHHHHHHHHHHHEEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 10493123 [H]