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The map label for this gene is xapB [H]

Identifier: 218548153

GI number: 218548153

Start: 783183

End: 784439

Strand: Direct

Name: xapB [H]

Synonym: EFER_0768

Alternate gene names: 218548153

Gene position: 783183-784439 (Clockwise)

Preceding gene: 218548152

Following gene: 218548154

Centisome position: 17.07

GC content: 41.21

Gene sequence:

>1257_bases
ATGAGTATCGCAACACGTTTAAAGGTGATGTCATTTTTGCAATATTTTATCTGGGGGAGTTGGTTAGTTACCCTGGGTTC
CTACATGATTAACACCTTACACTTTACTGGTGCCAACGTTGGCATGGTCTACAGTTCTAAAGGTATCGCAGCAATAATTA
TGCCTGGGATTATGGGTATAATTGCCGACAAATGGTTACGCGCAGAGCGTACCTATATGTTATGCCACCTGGTTTGTGCT
GGCGTGCTATTTTACGCAGCATCGGTTACTGATCCCGATACAATGTTTTGGGTGATGCTGATTAATGCAATGGCGTTTAT
GCCAACCATCGCTTTGTCGAATAGTGTCTCATATTCTTGCCTGGCACAAGCAGGGCTGGATCCGGTTACAAGTTTTCCAC
CTATTCGTGTTTTCGGCACGGTGGGATTTATTGTGGCCATGTGGTTAGTAAGCCTGTTGCATCTTGAACTTAGCAGTCTA
CAGCTTTATATCGCTTCTGGTGCTTCTTTAGTTTTGTCCGGTTACGCCTTAACTTTGCCAAAAATACCGGTAGCAGAAAA
GAAAGTTGCTACATCACTTGTTAGCAAGTTAGGTCTGGATGCTTTTGTATTATTTAAAAATCCACGGATGGCAATATTCT
TTTTATTTGCCATGATGTTAGGGGCAGTCTTACAAATTACTAATGTTTTTGGCAATCCATTCCTGCATGATTTTGCGCGT
AACCCACAGTTTGTCGACAGTTTTGTAGTGAAATATCCTTCTATTTTACTTTCTGTTTCGCAAATGGCGGAAGTCGGCTT
TATTCTTACCATTCCATTTTTTCTGAAGCGCTTTGGCATTAAAACCGTTATGTTAATGAGTATGGTTGCCTGGACATTGC
GATTTGGTTTCTTTGCTTTTGGTGATCCATCGCCGCTTGGTTTTATTCTACTGCTATTGTCGATGATTGTTTACGGATGC
GCTTTCGATTTCTTTAATATCTCTGGTTCTGTCTTTGTCGAGCAGGAGGTTGATTCCACCATTCGTGCCAGCGCGCAGGG
ATTATTTATGACCATGGTCAATGGTGTTGGTGCCTGGGTAGGCTCTATTCTAAGCGGTATGGCAGTGGACTATTTTACCA
TCGATGGTGTAAAAGACTGGCAAACTATTTGGCTGCTATTTGCTGGTTATTCACTGATATTAGCGTTTATATTTTCTGTA
TTCTTTAAATATAAACATGAACCAGAGAAAATAAGTCATAAATCACTGGCGCATTAA

Upstream 100 bases:

>100_bases
CTTCATTAATTTGATTTGTGGTTTTTTACGCAAAATCGCCTGAGAAAAATAACAATCGGCCTCACTGATGAGGCCATAAT
TATGCGATAAGGAAACGAAA

Downstream 100 bases:

>100_bases
TAACTATACGCTAATTAATTCGAGTTGCAGTCACCGCACATGTAACTTGAAGTATGACAAGTATATTAACTGGCGAGCAA
ATAGCCCGCCAGTTAAATGC

Product: xanthosine transporter

Products: Proton [Cytoplasm]; xanthosine [Cytoplasm] [C]

Alternate protein names: Xanthosine transporter [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVYSSKGIAAIIMPGIMGIIADKWLRAERTYMLCHLVCA
GVLFYAASVTDPDTMFWVMLINAMAFMPTIALSNSVSYSCLAQAGLDPVTSFPPIRVFGTVGFIVAMWLVSLLHLELSSL
QLYIASGASLVLSGYALTLPKIPVAEKKVATSLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
NPQFVDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAFGDPSPLGFILLLLSMIVYGC
AFDFFNISGSVFVEQEVDSTIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFTIDGVKDWQTIWLLFAGYSLILAFIFSV
FFKYKHEPEKISHKSLAH

Sequences:

>Translated_418_residues
MSIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVYSSKGIAAIIMPGIMGIIADKWLRAERTYMLCHLVCA
GVLFYAASVTDPDTMFWVMLINAMAFMPTIALSNSVSYSCLAQAGLDPVTSFPPIRVFGTVGFIVAMWLVSLLHLELSSL
QLYIASGASLVLSGYALTLPKIPVAEKKVATSLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
NPQFVDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAFGDPSPLGFILLLLSMIVYGC
AFDFFNISGSVFVEQEVDSTIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFTIDGVKDWQTIWLLFAGYSLILAFIFSV
FFKYKHEPEKISHKSLAH
>Mature_417_residues
SIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVYSSKGIAAIIMPGIMGIIADKWLRAERTYMLCHLVCAG
VLFYAASVTDPDTMFWVMLINAMAFMPTIALSNSVSYSCLAQAGLDPVTSFPPIRVFGTVGFIVAMWLVSLLHLELSSLQ
LYIASGASLVLSGYALTLPKIPVAEKKVATSLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFARN
PQFVDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAFGDPSPLGFILLLLSMIVYGCA
FDFFNISGSVFVEQEVDSTIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFTIDGVKDWQTIWLLFAGYSLILAFIFSVF
FKYKHEPEKISHKSLAH

Specific function: Nucleoside transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli nupG and yegT [H]

Homologues:

Organism=Escherichia coli, GI1788745, Length=418, Percent_Identity=92.1052631578947, Blast_Score=737, Evalue=0.0,
Organism=Escherichia coli, GI87082192, Length=418, Percent_Identity=58.8516746411483, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1788415, Length=435, Percent_Identity=27.5862068965517, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR004740 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46227; Mature: 46095

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVYSSKGIAAIIMPGIMGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
IADKWLRAERTYMLCHLVCAGVLFYAASVTDPDTMFWVMLINAMAFMPTIALSNSVSYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LAQAGLDPVTSFPPIRVFGTVGFIVAMWLVSLLHLELSSLQLYIASGASLVLSGYALTLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHCCCEEECC
KIPVAEKKVATSLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
CCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NPQFVDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPSPLGFILLLLSMIVYGCAFDFFNISGSVFVEQEVDSTIRASAQGLFMTMVNGVGAWV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GSILSGMAVDYFTIDGVKDWQTIWLLFAGYSLILAFIFSVFFKYKHEPEKISHKSLAH
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHCCCC
>Mature Secondary Structure 
SIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVYSSKGIAAIIMPGIMGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
IADKWLRAERTYMLCHLVCAGVLFYAASVTDPDTMFWVMLINAMAFMPTIALSNSVSYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LAQAGLDPVTSFPPIRVFGTVGFIVAMWLVSLLHLELSSLQLYIASGASLVLSGYALTLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHCCCEEECC
KIPVAEKKVATSLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
CCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NPQFVDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPSPLGFILLLLSMIVYGCAFDFFNISGSVFVEQEVDSTIRASAQGLFMTMVNGVGAWV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GSILSGMAVDYFTIDGVKDWQTIWLLFAGYSLILAFIFSVFFKYKHEPEKISHKSLAH
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; xanthosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + xanthosine [Periplasm] = Proton [Cytoplasm] + xanthosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7559336; 9205837; 9278503 [H]