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The map label for this gene is yfeT [H]

Identifier: 218548133

GI number: 218548133

Start: 763276

End: 764133

Strand: Direct

Name: yfeT [H]

Synonym: EFER_0745

Alternate gene names: 218548133

Gene position: 763276-764133 (Clockwise)

Preceding gene: 218548129

Following gene: 218548134

Centisome position: 16.63

GC content: 50.7

Gene sequence:

>858_bases
ATGTTGTACCTGACGAAAATACGCAATGCAGAAAGTGAATTTACCGGGAACGAGCAAAAAATAGCTGACTTTCTGCAGGC
TAAAGTGAGTGAGCTGAAATCCGTCTCTTCGCGCAAGATGGCGAAACAGCTCGGCATCAGCCAGTCGAGTATTGTGAAGT
TTGCCCAGAAGCTCGGCGCGCAAGGATTTACTGAATTGCGTATGGCGTTAATTGGCGAATACAGTGCCAGCCGGGAGAAA
ACGAATGCCACGGCGCTGCACTTGCACAGTTCGATTACCAGTGACGATTCGCTGGAAGTGATTGCCCGCAAACTGAATCG
CGAAAAAGAGCTGGCACTGGAGCAAACCTGCGCGTTACTCGATTACGCGCGGCTGCAAAAAATCATTGAGGTCATCAGTA
AAGCGCCGTTTATCCAGATAACAGGCCTGGGCGGGTCGGCGCTGGTGGGGCGCGATCTTTCATTCAAACTGATGAAAATT
GGTTATCGCGTGGCCTGTGAAGCCGACACGCACGTACAAGCTACCGTTTCCCAGGCGTTGAAAAAAGGTGATGTACAAAT
CGCTATCTCTTACAGCGGCAGTAAAAAAGAGATTTTGCTATGCGCCGAGGCAGCGCGAAAGCAGGGGGCAACGGTGATTG
CCATTACTTCACTGACTGACTCTCCGCTGCGGCGGTTGGCACATTTCACCCTCGATACCGTTTCTGGTGAAACCGAATGG
CGTAGCTCGTCGATGTCCACCCGCACGGCGCAAAATTCGGTTACCGATTTACTGTTTGTTGGGCTGGTACAACTTAATGA
TGTCGAGTCATTGAAAATGATTGAGCGCAGCAGTGAGCTAACACAACGCCTGAAATGA

Upstream 100 bases:

>100_bases
TGACAGACTTAAAGGAATCATTGAGTCTACACTCGCAGAGTGTGAAGAGCGTCATAAGAACTTAAGCGGAATTTTTGCTG
CCAGCCCAGGAGAGTGGAAG

Downstream 100 bases:

>100_bases
TGCATAAAGCAGCGACTGGATTGAGATTTTCCTGAATTAGTGAGCTGATCCGCAGCAATATTTTGTTTATCCTGTATTTT
CAGAGGGAATGGAGTGTAAC

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLYLTKIRNAESEFTGNEQKIADFLQAKVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREK
TNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALLDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEILLCAEAARKQGATVIAITSLTDSPLRRLAHFTLDTVSGETEW
RSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIERSSELTQRLK

Sequences:

>Translated_285_residues
MLYLTKIRNAESEFTGNEQKIADFLQAKVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREK
TNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALLDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEILLCAEAARKQGATVIAITSLTDSPLRRLAHFTLDTVSGETEW
RSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIERSSELTQRLK
>Mature_285_residues
MLYLTKIRNAESEFTGNEQKIADFLQAKVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREK
TNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALLDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEILLCAEAARKQGATVIAITSLTDSPLRRLAHFTLDTVSGETEW
RSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIERSSELTQRLK

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=285, Percent_Identity=97.1929824561404, Blast_Score=559, Evalue=1e-161,
Organism=Escherichia coli, GI87082130, Length=282, Percent_Identity=35.1063829787234, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI87082369, Length=260, Percent_Identity=25.7692307692308, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788159, Length=264, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31290; Mature: 31290

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLTKIRNAESEFTGNEQKIADFLQAKVSELKSVSSRKMAKQLGISQSSIVKFAQKLGA
CEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
QGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALL
CCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
DYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYRVACEADTHVQATVSQAL
HHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCHHHHHHCCEEEEECCCCHHHHHHHHHH
KKGDVQIAISYSGSKKEILLCAEAARKQGATVIAITSLTDSPLRRLAHFTLDTVSGETEW
HCCCEEEEEEECCCCCEEEEEEHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHH
RSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIERSSELTQRLK
HCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLYLTKIRNAESEFTGNEQKIADFLQAKVSELKSVSSRKMAKQLGISQSSIVKFAQKLGA
CEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
QGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALL
CCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
DYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYRVACEADTHVQATVSQAL
HHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCHHHHHHCCEEEEECCCCHHHHHHHHHH
KKGDVQIAISYSGSKKEILLCAEAARKQGATVIAITSLTDSPLRRLAHFTLDTVSGETEW
HCCCEEEEEEECCCCCEEEEEEHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHH
RSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIERSSELTQRLK
HCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA