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The map label for this gene is yeeJ [C]

Identifier: 218548054

GI number: 218548054

Start: 667397

End: 669589

Strand: Direct

Name: yeeJ [C]

Synonym: EFER_0663

Alternate gene names: 218548054

Gene position: 667397-669589 (Clockwise)

Preceding gene: 218548053

Following gene: 218548055

Centisome position: 14.54

GC content: 48.84

Gene sequence:

>2193_bases
ATGTCACAGGGGATGTGCATGCTGCGATGGAAACGCTGTATTATGCTAACATTTATCTCTGGAGCTGCTTTTGCGGCTCC
AGAGATAAATGTTGAGCATAAAGAATCGTTACCTGATTTAGGTAGTCAGGCCGCACAACAGGAAGAACAAACTAACAAGG
GTAAATCGCTAAAAGAGCGTGGTGCCGATTACGTCATTAACTCCGCCACGCAAGGGTTTGAAAACCTGACACCCGAGGCG
CTGGAGTCCCAGGCCAGAAGCTATCTGCAAAGTCAAATTACCTCTACGACACAATCTTATATTGAGGATACACTCTCCCC
CTACGGTAAGGTCCGAACGAATCTTTCTCTTGGTCAGGGCGGCGATCTGGATGGCAGTTCCATCGACTATTTTGTTCCCT
GGTATGATAATCAAACTACTGTTTATTTCAGCCAATTTTCCGCACAACGAAAAGAAGATCGTACGATCGGGAATATTGGG
CTTGGTGTAAGACATAATTTTGAAAAATGGTTGTTGGGTGGAAATATATTTTATGATTATGATTTTACCCGAGGACATCG
CCGTTTAGGTTTAGGCGCCGAAGCGTGGACTGATTATTTAAAATTCTCTGGCAACTATTATCACCCGCTTTCTGATTGGA
AAGACTCCGAAGATTTTGATTTTTATGAGGAGCGTCCTGCGCGCGGCTGGGATATTCGCGCCGACGCCTGGCTACCCGCT
TACCCGCAGCTTGGCGGTAAAATCGTTTTCGAACAGTATTACGGTGATGAAGTCGCGCTTTTTGGAACTGATAATCTGGA
GAAAGATCCCTTCGCCGTCACGCTGGGTGTGAAATACCAGCCCGTACCGCTCATTGCCGTCGGTACAGATTTCAAAGCTG
GCACTGGCGATAATACCGATCTTTCTGTTAACGCAACGCTGAACTACCAGTTTGGCGTCCCGCTCAAAGACCAGCTTGAT
CCTGACAAAGTGAGCGCGGCTCACTCGCTCATGGGCAGCCGTCACGACTTTGTTGAACGTAACAACTTTATTGTTCTGGA
ATACAAAGAGAAAGATCCCCTCGATGTCACTTTGTGGCTGAAAGCTGATGCGACGAATGAACATCCCGAGTGCGTGATTA
AAGATACGCCAGAAGCAGCCATCGGGCTGGAAAAATGTAAGTGGACCATTAACGCGCTCATTAATCATCACTACAAAATC
GTTGCTGCCTCCTGGCAGGCGAAAAACAATGCTGCACGTACGCTGGTGATGCCGGTTATCAAAGAAAATACGCTTACTGA
AGGGACCAACAACCACTGGAATCTGGTGCTGCCTGCCTGGCAGTACAGCTCTGATAAAGCCGACCAGGAAAAACTCAATA
CCTGGCGGGTACGTCTGGCGCTGGAAGATGAAAAGGGCAATCGGCAGAACTCCGGCGTGGTGGAAATTACCGTTCAGCAG
GACCGTAAAATTGAGCTCATTGTTAACAACATCGCCAATGTACCGGATGAGAACAATCACAGCCACGAAGCCAGCGCGCA
AGCGGATGGTGTAGATGGTGTCGTCATGGATCTCGACGTTACCGATAGCTTTGGCGACAACACTGACCGTAACGGTAATG
TCTTGCCGCAGGATAATCTCAGCCCGCAGCTGTTTGATGCCAACGATAAAAAAGTGACGCTGACGAATAAACCCTGCACC
ACCGAGGTGCCGTGCGTTTTTATCGCCAAACAAGATAAAGAAAAGGGGACCGTTACGCTCTCCAGTACGTTGCCCGGCAC
TTTCCGCTGGAAGGCGAAAGCCGCACCTTACGATGACAGTAACTATGTTGACGTAACGTTCCTGGGTTCTGACATCGGCG
GGCTGAATGCTTTTATCTACCGCGTTGGTGCGGCTAAGCCCGTCAATCTTATCGGTAACAAAGAACCGTTGCCCCTCAAT
AGCCGCTATCGCTTTGTGCTGTGGCGCGACGCTAACAAAGACGGCGTGTTTCAGCTTTCTGAGAAGCTCACTGACGACGA
GATGAAACAGTATGACTACCAGTGGGAATTCACGGGGAATAGCGTAAATGGCAATACCGGCGCGCAAACCAATACCGCTA
ATGTCGATATAGCGATCCCGGTAACCAACAAGGAAGCGGCAGCAAAGTTTAATGCTCAGGTAACCGATGGTGTGCAGGGA
TACGGTTTGCAGGTCAATTACAGCAAGAAATAG

Upstream 100 bases:

>100_bases
AAATCACTGTGTTATAAATTTAAGATTATATTTAGTTTTCCTGGCGTGCCTTTCTGAACAATCTGGAATAGAATATTAAA
GCTTATTTTAAGCATTATTA

Downstream 100 bases:

>100_bases
GGTCGGCGCCATGGCTGATCGGGCCACCGCTGAATATTAATCAAGGAGAGTGTTTATGAAACCTCATATGAAACGTGGCC
TGACAAAAGTCGCGCTGGCA

Product: intimin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 729

Protein sequence:

>730_residues
MSQGMCMLRWKRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVINSATQGFENLTPEA
LESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIG
LGVRHNFEKWLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRADAWLPA
YPQLGGKIVFEQYYGDEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLKDQLD
PDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEAAIGLEKCKWTINALINHHYKI
VAASWQAKNNAARTLVMPVIKENTLTEGTNNHWNLVLPAWQYSSDKADQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQ
DRKIELIVNNIANVPDENNHSHEASAQADGVDGVVMDLDVTDSFGDNTDRNGNVLPQDNLSPQLFDANDKKVTLTNKPCT
TEVPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLN
SRYRFVLWRDANKDGVFQLSEKLTDDEMKQYDYQWEFTGNSVNGNTGAQTNTANVDIAIPVTNKEAAAKFNAQVTDGVQG
YGLQVNYSKK

Sequences:

>Translated_730_residues
MSQGMCMLRWKRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVINSATQGFENLTPEA
LESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIG
LGVRHNFEKWLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRADAWLPA
YPQLGGKIVFEQYYGDEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLKDQLD
PDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEAAIGLEKCKWTINALINHHYKI
VAASWQAKNNAARTLVMPVIKENTLTEGTNNHWNLVLPAWQYSSDKADQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQ
DRKIELIVNNIANVPDENNHSHEASAQADGVDGVVMDLDVTDSFGDNTDRNGNVLPQDNLSPQLFDANDKKVTLTNKPCT
TEVPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLN
SRYRFVLWRDANKDGVFQLSEKLTDDEMKQYDYQWEFTGNSVNGNTGAQTNTANVDIAIPVTNKEAAAKFNAQVTDGVQG
YGLQVNYSKK
>Mature_729_residues
SQGMCMLRWKRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVINSATQGFENLTPEAL
ESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGL
GVRHNFEKWLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRADAWLPAY
PQLGGKIVFEQYYGDEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLKDQLDP
DKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEAAIGLEKCKWTINALINHHYKIV
AASWQAKNNAARTLVMPVIKENTLTEGTNNHWNLVLPAWQYSSDKADQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQD
RKIELIVNNIANVPDENNHSHEASAQADGVDGVVMDLDVTDSFGDNTDRNGNVLPQDNLSPQLFDANDKKVTLTNKPCTT
EVPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNS
RYRFVLWRDANKDGVFQLSEKLTDDEMKQYDYQWEFTGNSVNGNTGAQTNTANVDIAIPVTNKEAAAKFNAQVTDGVQGY
GLQVNYSKK

Specific function: Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 Big-1 (bacterial Ig-like domain 1) domains [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=407, Percent_Identity=35.3808353808354, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI145693120, Length=444, Percent_Identity=31.3063063063063, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR015217 [H]

Pfam domain/function: PF02369 Big_1; PF07979 Intimin_C; PF09134 Invasin_D3 [H]

EC number: NA

Molecular weight: Translated: 81649; Mature: 81518

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQGMCMLRWKRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKER
CCCCEEHHHHHHEEEEEEECCCEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCHHHC
GADYVINSATQGFENLTPEALESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQG
CCCEEEECHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCC
GDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHNFEKWLLGGNIFYDY
CCCCCCCEEEEEEEECCCEEEEEECCCCHHHHCCCCCCCCCCEECCCHHEEECCEEEEEE
DFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRADAWLPA
CCCCCCCEECCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCCEEECCCCCCC
YPQLGGKIVFEQYYGDEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTD
CCCCCCEEEEEEECCCEEEEEECCCCCCCCEEEEEECEECCEEEEEECCCCCCCCCCCCE
LSVNATLNYQFGVPLKDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWL
EEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCEEEEEE
KADATNEHPECVIKDTPEAAIGLEKCKWTINALINHHYKIVAASWQAKNNAARTLVMPVI
EECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEE
KENTLTEGTNNHWNLVLPAWQYSSDKADQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQ
CCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCCEEEEEEEEECCCCCCCCCCEEEEEECC
DRKIELIVNNIANVPDENNHSHEASAQADGVDGVVMDLDVTDSFGDNTDRNGNVLPQDNL
CCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
SPQLFDANDKKVTLTNKPCTTEVPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDS
CCCEECCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCC
NYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNSRYRFVLWRDANKDGVFQLS
CEEEEEEECCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEEECCCCCCEEHHH
EKLTDDEMKQYDYQWEFTGNSVNGNTGAQTNTANVDIAIPVTNKEAAAKFNAQVTDGVQG
HHCCHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCHHHHEECCEECCCCCC
YGLQVNYSKK
CEEEEEECCC
>Mature Secondary Structure 
SQGMCMLRWKRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKER
CCCEEHHHHHHEEEEEEECCCEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCHHHC
GADYVINSATQGFENLTPEALESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQG
CCCEEEECHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCC
GDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHNFEKWLLGGNIFYDY
CCCCCCCEEEEEEEECCCEEEEEECCCCHHHHCCCCCCCCCCEECCCHHEEECCEEEEEE
DFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRADAWLPA
CCCCCCCEECCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCCEEECCCCCCC
YPQLGGKIVFEQYYGDEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTD
CCCCCCEEEEEEECCCEEEEEECCCCCCCCEEEEEECEECCEEEEEECCCCCCCCCCCCE
LSVNATLNYQFGVPLKDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWL
EEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCEEEEEE
KADATNEHPECVIKDTPEAAIGLEKCKWTINALINHHYKIVAASWQAKNNAARTLVMPVI
EECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEE
KENTLTEGTNNHWNLVLPAWQYSSDKADQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQ
CCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCCEEEEEEEEECCCCCCCCCCEEEEEECC
DRKIELIVNNIANVPDENNHSHEASAQADGVDGVVMDLDVTDSFGDNTDRNGNVLPQDNL
CCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
SPQLFDANDKKVTLTNKPCTTEVPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDS
CCCEECCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCC
NYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNSRYRFVLWRDANKDGVFQLS
CEEEEEEECCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEEECCCCCCEEHHH
EKLTDDEMKQYDYQWEFTGNSVNGNTGAQTNTANVDIAIPVTNKEAAAKFNAQVTDGVQG
HHCCHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCHHHHEECCEECCCCCC
YGLQVNYSKK
CEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3304658; 1693333; 10514372 [H]