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The map label for this gene is engA [H]

Identifier: 218548052

GI number: 218548052

Start: 665455

End: 666927

Strand: Direct

Name: engA [H]

Synonym: EFER_0661

Alternate gene names: 218548052

Gene position: 665455-666927 (Clockwise)

Preceding gene: 218548051

Following gene: 218548053

Centisome position: 14.5

GC content: 51.32

Gene sequence:

>1473_bases
ATGGTACCTGTGGTCGCGCTTGTCGGGCGCCCTAACGTCGGAAAATCCACGTTATTTAACCGTCTAACTCGCACACGAGA
TGCGCTGGTTGCGGATTTCCCAGGTCTGACTCGTGACCGTAAATACGGTCGTGCAGAAATTGAAGGCCGCGAGTTTATTT
GTATTGATACTGGCGGGATTGATGGCACCGAAGACGGTGTAGAGACTCGTATGGCAGAACAATCGCTGCTTGCGATCGAA
GAAGCAGATGTTGTGCTGTTTATGGTCGATGCGCGCGCTGGCCTGATGCCTGCGGATGAAGCGATTGCCAAACATCTGCG
CTCCCGCGAAAAGCCAACCTTCCTGGTGGCAAACAAAACTGACGGGTTGGATCCTGATCAGGCGGTGGTTGATTTCTACT
CGCTTGGTTTAGGTGAAATCTACCCGATCGCCGCATCTCACGGTCGTGGCGTATTAAGTCTGCTGGAGCACGTGCTGCTG
CCGTGGATGGAAGATCTCGCACCACAAGAAGAAGTGGATGAAGACGCTGAATACTGGGCGCAATTTGAAGCAGAAGAAAA
CGGCGAAGAAGAAGAGGAAGATGACTTCGACCCGCAAAGCCTGCCAATCAAACTGGCGATAGTGGGTCGTCCAAACGTTG
GTAAGTCTACACTCACTAACCGTATCCTTGGCGAAGAGCGCGTTGTGGTTTATGACATGCCAGGCACCACGCGTGACAGT
ATTTACATTCCAATGGAACGCGATGGACGTGAGTATGTGCTCATCGATACTGCCGGCGTACGTAAACGCGGCAAAATCAC
CGATGCGGTAGAGAAATTCTCCGTAATCAAAACATTGCAGGCGATTGAGGATGCCAACGTGGTGATGTTGGTGATTGATG
CTCGCGAAGGTATTTCCGATCAGGATCTCTCCCTGCTGGGCTTTATTCTCAATAGTGGGCGCTCACTTGTGATTGTAGTG
AACAAGTGGGACGGCCTGAGCCAGGAAGTGAAAGAGCAAGTAAAAGAGACGCTGGACTTCCGTCTGGGCTTTATCGACTT
TGCTCGCGTGCATTTTATTTCTGCATTACACGGCAGCGGCGTTGGTAACCTATTTGAGTCAGTACGTGAAGCGTATGACA
GTTCCACTCGTCGTGTGGGGACATCTATGTTGACGCGTATCATGACCATGGCGGTTGAAGATCACCAGCCGCCGCTGGTT
CGCGGGCGTCGTGTGAAGCTGAAATATGCCCACGCCGGTGGTTACAATCCGCCGATTGTGGTGATTCACGGCAACCAGGT
GAAAGACCTGCCTGATTCGTACAAACGCTACTTGATGAATTACTTCCGCAAGTCTCTGGACGTGATGGGTACGCCGATTC
GTATTCAGTTCAAAGAAGGGGAAAACCCATATGCGAACAAGCGTAACACCCTGACGCCGACCCAGATGCGCAAGCGTAAG
CGTTTGATGAAGCATATTAAGAAAAGTAAGTAA

Upstream 100 bases:

>100_bases
TTAAAAAACGGCTCCTGGACAAGGGGCCGTTTTCCTGTTTTTAACAACGGCGCAAATTTGTGAGCGTTGTTTGATGATTT
ATAAAAATGAGGCTTTAAAC

Downstream 100 bases:

>100_bases
TCACTTATCTGGTTTCCCTTTCCAAACGGAGAGGGAAACTGAACAACAGGCGAGGAGTATTTATGGAACTCAACTGCCCA
ATCTGCCATAACCCTCTCGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
IYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVV
NKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLV
RGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
RLMKHIKKSK

Sequences:

>Translated_490_residues
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
IYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVV
NKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLV
RGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
RLMKHIKKSK
>Mature_490_residues
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
IYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVV
NKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLV
RGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
RLMKHIKKSK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=490, Percent_Identity=99.5918367346939, Blast_Score=997, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=91, Percent_Identity=40.6593406593407, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=172, Percent_Identity=29.0697674418605, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=31.25, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 55024; Mature: 55024

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEECCCC
DGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKT
CCCCHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECC
DGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWA
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHHHHH
QFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
IYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISD
EEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
QDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSG
CHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEE
VIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
RLMKHIKKSK
HHHHHHHHCC
>Mature Secondary Structure
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEECCCC
DGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKT
CCCCHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECC
DGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWA
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHHHHH
QFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
IYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISD
EEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
QDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSG
CHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEE
VIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
RLMKHIKKSK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA