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The map label for this gene is siiCA [H]

Identifier: 218547938

GI number: 218547938

Start: 543025

End: 544380

Strand: Direct

Name: siiCA [H]

Synonym: EFER_0541

Alternate gene names: 218547938

Gene position: 543025-544380 (Clockwise)

Preceding gene: 218547937

Following gene: 218547939

Centisome position: 11.83

GC content: 52.21

Gene sequence:

>1356_bases
ATGGCGCTATTACATATTAAAAACCGTAAAAATAAAGGTCTTATTTTTTTAATGGGTTGTATTGTCATGGGGAAAAACAC
ACTTGCTGCGCCATTACCGCAATGGGCGAATGCTCCTGCGGTTACGCCTGTTGCCAGTTTATCCTTACAGGAAAGCATAT
TGCGCGCCTTTGCGCGCAACCCCGACGTCACCCAACAGGCGGCGCAGATAGGTATTGGCGAAGCGCAAATCGATGAAGCC
AAAAGTGCCTGGTATCCACACGTTGGATTAACCGGCAACGCGGGGCCGTCCCGGCAAACGGACTCCAGCGGCAGGCTGGA
TAACAACGTCTCTTATGGCATAACCCTGACGCAGCTGGTGTATGACTTCGGTAAAACAGATAACGATATCAAACTACAAA
CCGCCGCACGCGACAGCTACCGTTTTAAACTGATGGCAACCTTAACTGACGTAGCCGAAAAGACGGCGACGACCTATATG
GAAGTGAGCCGATATCAGGCGTTGTGTGACGCTGCGCAGCGTAATATCAACTCGCTGGAAAACGTCTACAACATGGCGGC
ACTGCGCGCCAACGCCGGGCTTAACTCATCATCCGATGAATTACAGGCACAGACGCGTATAGCGGCAATGCGCTCGACGC
TGGAGCAATACCAGGCGCAAATGGCAAGCGCCAAAGCGCAACTGGCGGTGCTCACTGGTGTACAGCCGGAGAGGATAGCC
GCGCCACCTGCTGAATTAGCCGAGCAGCCAGTGTCGCTAAAAAATATTGATTACCAGTCCATACCGCTGGTGCTGGCTGC
TGAAAACTTACGCCAGTCTGCCCAGTACGGCGTGGAGAAAACCAAATCGCAATACTGGCCGACGCTCAGTATTCAGGGCG
GCAAAACGCGCTACCAGACCAGCGACCGCTCGTACTGGGATGACCAGTTACAACTGAACGTCAACGCGCCGTTGTATCAG
GGCGGCGCGGTTTCAGCCCAGGTGCAACAGGCCGAAGGGCAACAAAAAATCTCTGCCTCGCAGGTTGAGCAGGCGAAATT
AGATGTTATGCAACGGGCGTCGGTGGCGTATGCCAACTGGACTGGGGCACGGGGACGTGAAGAGGCCGGTTTAGCGCAAT
CCGAAAGTGCGCACAGAACGCGGGATGTTTATCAGAATGAATATAAATTGGGTAACCGAAGCCTGAACGATCTATTAACC
GTCGAGCAAGATGTTTTTCAGGCGCAATCGGCTGAAATAAATGCCAATTATGATGGCTGGGTCGCCGCAGTGAATTATGC
CGCTGCGGTAAATAACCTTATTCCATTAGCGGGAATTAAACAGGGCTTATACAACGACTTACCCGACTTGAAATAA

Upstream 100 bases:

>100_bases
GTGAACAAAAGAAATGTGCAAGTTATTGGCCTTCTTTATTAAAAAGAGGTTGGTTATAAAAACCAACTAAAATAAGGACC
TGGAAGGAAGTGACTTAACT

Downstream 100 bases:

>100_bases
TCCTGCCATTATTAATATCAGGTATGCATCGTTGTTAAGTGATTACCTTTGTCTTATTTAGATAAATGGACTCGCTAAGG
ATTTGCGCCATTTATCAGGG

Product: outer membrane transport protein, type I secretion

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MALLHIKNRKNKGLIFLMGCIVMGKNTLAAPLPQWANAPAVTPVASLSLQESILRAFARNPDVTQQAAQIGIGEAQIDEA
KSAWYPHVGLTGNAGPSRQTDSSGRLDNNVSYGITLTQLVYDFGKTDNDIKLQTAARDSYRFKLMATLTDVAEKTATTYM
EVSRYQALCDAAQRNINSLENVYNMAALRANAGLNSSSDELQAQTRIAAMRSTLEQYQAQMASAKAQLAVLTGVQPERIA
APPAELAEQPVSLKNIDYQSIPLVLAAENLRQSAQYGVEKTKSQYWPTLSIQGGKTRYQTSDRSYWDDQLQLNVNAPLYQ
GGAVSAQVQQAEGQQKISASQVEQAKLDVMQRASVAYANWTGARGREEAGLAQSESAHRTRDVYQNEYKLGNRSLNDLLT
VEQDVFQAQSAEINANYDGWVAAVNYAAAVNNLIPLAGIKQGLYNDLPDLK

Sequences:

>Translated_451_residues
MALLHIKNRKNKGLIFLMGCIVMGKNTLAAPLPQWANAPAVTPVASLSLQESILRAFARNPDVTQQAAQIGIGEAQIDEA
KSAWYPHVGLTGNAGPSRQTDSSGRLDNNVSYGITLTQLVYDFGKTDNDIKLQTAARDSYRFKLMATLTDVAEKTATTYM
EVSRYQALCDAAQRNINSLENVYNMAALRANAGLNSSSDELQAQTRIAAMRSTLEQYQAQMASAKAQLAVLTGVQPERIA
APPAELAEQPVSLKNIDYQSIPLVLAAENLRQSAQYGVEKTKSQYWPTLSIQGGKTRYQTSDRSYWDDQLQLNVNAPLYQ
GGAVSAQVQQAEGQQKISASQVEQAKLDVMQRASVAYANWTGARGREEAGLAQSESAHRTRDVYQNEYKLGNRSLNDLLT
VEQDVFQAQSAEINANYDGWVAAVNYAAAVNNLIPLAGIKQGLYNDLPDLK
>Mature_450_residues
ALLHIKNRKNKGLIFLMGCIVMGKNTLAAPLPQWANAPAVTPVASLSLQESILRAFARNPDVTQQAAQIGIGEAQIDEAK
SAWYPHVGLTGNAGPSRQTDSSGRLDNNVSYGITLTQLVYDFGKTDNDIKLQTAARDSYRFKLMATLTDVAEKTATTYME
VSRYQALCDAAQRNINSLENVYNMAALRANAGLNSSSDELQAQTRIAAMRSTLEQYQAQMASAKAQLAVLTGVQPERIAA
PPAELAEQPVSLKNIDYQSIPLVLAAENLRQSAQYGVEKTKSQYWPTLSIQGGKTRYQTSDRSYWDDQLQLNVNAPLYQG
GAVSAQVQQAEGQQKISASQVEQAKLDVMQRASVAYANWTGARGREEAGLAQSESAHRTRDVYQNEYKLGNRSLNDLLTV
EQDVFQAQSAEINANYDGWVAAVNYAAAVNNLIPLAGIKQGLYNDLPDLK

Specific function: Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=396, Percent_Identity=25.2525252525253, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 49257; Mature: 49126

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLHIKNRKNKGLIFLMGCIVMGKNTLAAPLPQWANAPAVTPVASLSLQESILRAFARN
CEEEEECCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
PDVTQQAAQIGIGEAQIDEAKSAWYPHVGLTGNAGPSRQTDSSGRLDNNVSYGITLTQLV
CCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
YDFGKTDNDIKLQTAARDSYRFKLMATLTDVAEKTATTYMEVSRYQALCDAAQRNINSLE
HHHCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVYNMAALRANAGLNSSSDELQAQTRIAAMRSTLEQYQAQMASAKAQLAVLTGVQPERIA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHCC
APPAELAEQPVSLKNIDYQSIPLVLAAENLRQSAQYGVEKTKSQYWPTLSIQGGKTRYQT
CCCHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEC
SDRSYWDDQLQLNVNAPLYQGGAVSAQVQQAEGQQKISASQVEQAKLDVMQRASVAYANW
CCCCCCCCEEEEEECCCEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECC
TGARGREEAGLAQSESAHRTRDVYQNEYKLGNRSLNDLLTVEQDVFQAQSAEINANYDGW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCH
VAAVNYAAAVNNLIPLAGIKQGLYNDLPDLK
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALLHIKNRKNKGLIFLMGCIVMGKNTLAAPLPQWANAPAVTPVASLSLQESILRAFARN
EEEEECCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
PDVTQQAAQIGIGEAQIDEAKSAWYPHVGLTGNAGPSRQTDSSGRLDNNVSYGITLTQLV
CCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
YDFGKTDNDIKLQTAARDSYRFKLMATLTDVAEKTATTYMEVSRYQALCDAAQRNINSLE
HHHCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVYNMAALRANAGLNSSSDELQAQTRIAAMRSTLEQYQAQMASAKAQLAVLTGVQPERIA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHCC
APPAELAEQPVSLKNIDYQSIPLVLAAENLRQSAQYGVEKTKSQYWPTLSIQGGKTRYQT
CCCHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEC
SDRSYWDDQLQLNVNAPLYQGGAVSAQVQQAEGQQKISASQVEQAKLDVMQRASVAYANW
CCCCCCCCEEEEEECCCEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECC
TGARGREEAGLAQSESAHRTRDVYQNEYKLGNRSLNDLLTVEQDVFQAQSAEINANYDGW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCH
VAAVNYAAAVNNLIPLAGIKQGLYNDLPDLK
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]