Click here to switch to the map view.

The map label for this gene is higB-1 [H]

Identifier: 218547934

GI number: 218547934

Start: 537785

End: 538087

Strand: Direct

Name: higB-1 [H]

Synonym: EFER_0537

Alternate gene names: 218547934

Gene position: 537785-538087 (Clockwise)

Preceding gene: 218547929

Following gene: 218547935

Centisome position: 11.72

GC content: 40.92

Gene sequence:

>303_bases
ATGGCTCAAAAGAATAATATAAGGAGTTTTCGTGATGCCTGGCTGGCTGATTTTTTTGTCCACTCAACGCCACATAGAAA
GATTCCTGCTGAAATCCATACCACATTATCAAGAAAATTGGACATCATTAATGCTGCCACTTCTCATCGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATATTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTATTTAGATCCACACAACTACTAA

Upstream 100 bases:

>100_bases
CGCAGGGAGGGATGGCGCAAATGGAGTTGATTATTGCACTTGCGCACAGTGCTTGTGTGCATTAAAATGATTAAATAATG
GACAAAGAGATGACAATGGA

Downstream 100 bases:

>100_bases
AACATAGCTGTCGTATTGACGAGAAAGGTAAAACCATGAAACAGGCAACAAGAAAACCGACGACACCCGGAGATATTCTT
CTCTATGAATATCTGGAGCC

Product: RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 100; Mature: 99

Protein sequence:

>100_residues
MAQKNNIRSFRDAWLADFFVHSTPHRKIPAEIHTTLSRKLDIINAATSHRDLRSPPGNRYEELSGKLQEYSSIRVNKQYR
LIFKWVNGKAEELYLDPHNY

Sequences:

>Translated_100_residues
MAQKNNIRSFRDAWLADFFVHSTPHRKIPAEIHTTLSRKLDIINAATSHRDLRSPPGNRYEELSGKLQEYSSIRVNKQYR
LIFKWVNGKAEELYLDPHNY
>Mature_99_residues
AQKNNIRSFRDAWLADFFVHSTPHRKIPAEIHTTLSRKLDIINAATSHRDLRSPPGNRYEELSGKLQEYSSIRVNKQYRL
IFKWVNGKAEELYLDPHNY

Specific function: Inhibits translation by cleavage of mRNA [H]

COG id: COG3549

COG function: function code R; Plasmid maintenance system killer protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007711 [H]

Pfam domain/function: PF05015 Plasmid_killer [H]

EC number: NA

Molecular weight: Translated: 11811; Mature: 11680

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKNNIRSFRDAWLADFFVHSTPHRKIPAEIHTTLSRKLDIINAATSHRDLRSPPGNRY
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EELSGKLQEYSSIRVNKQYRLIFKWVNGKAEELYLDPHNY
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCC
>Mature Secondary Structure 
AQKNNIRSFRDAWLADFFVHSTPHRKIPAEIHTTLSRKLDIINAATSHRDLRSPPGNRY
CCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EELSGKLQEYSSIRVNKQYRLIFKWVNGKAEELYLDPHNY
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]