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The map label for this gene is hycA [H]

Identifier: 218547767

GI number: 218547767

Start: 363617

End: 364078

Strand: Direct

Name: hycA [H]

Synonym: EFER_0352

Alternate gene names: 218547767

Gene position: 363617-364078 (Clockwise)

Preceding gene: 218547759

Following gene: 218547768

Centisome position: 7.92

GC content: 48.48

Gene sequence:

>462_bases
ATGACTATTTGGGAAATAAGCGAAAAAGCCGATTACATCGCGCAGCGGCACCGTCGCCTACAGGACCAGTGGCATATTTA
CTGCAACTCACTGGTCCAGGGGATCACGCTATCAAAAGCACATTTGCATCACGGAATGAGTTGTGCGGCAGAAAAAGACC
TCTGCTTCGTTCTCTTCGAACACTTCCGTATCTACGTCACCCTGGCGGATGGTTTTAATAATCACATCATTGAGTATTAC
ATCGAATCCAAAGAGCCCAACAGTAAACAACTGATTGGGCGAGCAGAGTTGTCAATAGACGGCAAGATAGACGGTGAGAT
CAGCAACCGTGATCGCGAGCAAGTGCTTGAACACTATCTCGGCAAAATCGCCCGCGTCTATGACGGCCTGTATGCCGCTG
TAGAAAGTAATGCGCCAGTGGATCTGGGCTTACTGATTGATGAGCAAAACCCGGTCGTATAA

Upstream 100 bases:

>100_bases
AATCACAGTGATTCAGGTGATTTACTGATAAAACAATGAGTTAAAAAATGGCATGAAAAATGCTTATAGCTGGTCGTCTC
TGTTAACCGGGTAACCTGAC

Downstream 100 bases:

>100_bases
GCCGCCGTTTTGTCCGTATAGCGCCGTCACGGGCGTTGTACTGCATCACAACTAACTGGAAATGGGCGTGTCGAGGGATG
TCAAAAATGACATCTCATCG

Product: formate hydrogenlyase regulatory protein HycA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKAHLHHGMSCAAEKDLCFVLFEHFRIYVTLADGFNNHIIEYY
IESKEPNSKQLIGRAELSIDGKIDGEISNRDREQVLEHYLGKIARVYDGLYAAVESNAPVDLGLLIDEQNPVV

Sequences:

>Translated_153_residues
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKAHLHHGMSCAAEKDLCFVLFEHFRIYVTLADGFNNHIIEYY
IESKEPNSKQLIGRAELSIDGKIDGEISNRDREQVLEHYLGKIARVYDGLYAAVESNAPVDLGLLIDEQNPVV
>Mature_152_residues
TIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKAHLHHGMSCAAEKDLCFVLFEHFRIYVTLADGFNNHIIEYYI
ESKEPNSKQLIGRAELSIDGKIDGEISNRDREQVLEHYLGKIARVYDGLYAAVESNAPVDLGLLIDEQNPVV

Specific function: Regulatory protein for the formate hydrogenlyase system. Could act by directly interacting with fhlA or by preventing the binding of fhlA to the upstream activatory sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789080, Length=151, Percent_Identity=76.158940397351, Blast_Score=247, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021285 [H]

Pfam domain/function: PF11046 HycA_repressor [H]

EC number: NA

Molecular weight: Translated: 17586; Mature: 17455

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKAHLHHGMSCAAEKDLCFVLFE
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHH
HFRIYVTLADGFNNHIIEYYIESKEPNSKQLIGRAELSIDGKIDGEISNRDREQVLEHYL
HHEEEEEEECCCCCCEEEEEEECCCCCHHHEEEEEEEEECCEECCCCCCCCHHHHHHHHH
GKIARVYDGLYAAVESNAPVDLGLLIDEQNPVV
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
TIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKAHLHHGMSCAAEKDLCFVLFE
CEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHH
HFRIYVTLADGFNNHIIEYYIESKEPNSKQLIGRAELSIDGKIDGEISNRDREQVLEHYL
HHEEEEEEECCCCCCEEEEEEECCCCCHHHEEEEEEEEECCEECCCCCCCCHHHHHHHHH
GKIARVYDGLYAAVESNAPVDLGLLIDEQNPVV
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]