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The map label for this gene is ygdL [H]

Identifier: 218547676

GI number: 218547676

Start: 270819

End: 271625

Strand: Direct

Name: ygdL [H]

Synonym: EFER_0255

Alternate gene names: 218547676

Gene position: 270819-271625 (Clockwise)

Preceding gene: 218547675

Following gene: 218547679

Centisome position: 5.9

GC content: 55.27

Gene sequence:

>807_bases
ATGTCTGTGGTAATTAGTGATGCCTGGCGTCAGCGTTTTGGTGGCACAGCGCGTCTGTATGGTGAAAAAGCGTTGCAACT
GTTTGCTGATGCACATATTTGTGTGGTCGGTATTGGCGGTGTCGGCTCCTGGGCGGCGGAAGCGCTGGCGCGTACGGGGA
TTGGCGCAATCACGCTTATCGATATGGATGATGTGTGCGTCACCAATACCAATCGGCAAATTCACGCGCTGCGAGATAAC
GTCGGGCTGGCCAAAGCGGAAGTAATGGCGGAGCGTATTCGCCAGATTAACCCGGAGTGCCGTGTAACGGTGGTGGATGA
CTTCGTGACGCCGGATAACGTAGCGCAATATATGAGTGCCGGTTATTCGTACGTGATTGATGCCATTGATAGTGTGCGAC
CCAAAGCGGCGCTGATTGCTCATTGTCGGCGCAACAAAATCCCTCTGGTCACGACTGGTGGTGCTGGTGGGCAGATTGAT
CCGACGCAGATTCAGGTTACCGATCTGGCTAAAACGATTCAGGACCCGCTGGCGGCGAAGTTGCGCGAGCGCCTGAAAAG
CGATTTTGGCGTAGTGAAAAACAGCAAAGGTAAGCTCGGCGTGGATTGCGTGTTCTCTACCGAAGCGCTGGTGTACCCGC
AGTCAGACGGTACGGTGTGCGCGATGAAAGCCACGGCAGAAGGGCCGAAGCGGATGGATTGTGCATCTGGATTTGGGGCG
GCGACGATGGTGACCGCCACCTTTGGTTTTGTTGCGGTTTCTCATGCGCTGAAGAAGATGATGGTGAAAGCGGCGCGTCA
GGGGTAA

Upstream 100 bases:

>100_bases
GCAGGTAACGTCTTTAGCGGCTGATGTGATATTCTGTATACCGTTTTGACGGATATGACAGGGTGAGGGATAACCTCACC
CTTTTTAATTCTGAGGTGCT

Downstream 100 bases:

>100_bases
ACAATCAGGTCGGATGCGACGTGAACGTCTTATCCGACCTGGTTTTGTGCTTAACCCTGCTTCGCCGCCGCGATAATCGC
CTCACTTAACGCATTCAACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDN
VGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSAGYSYVIDAIDSVRPKAALIAHCRRNKIPLVTTGGAGGQID
PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGA
ATMVTATFGFVAVSHALKKMMVKAARQG

Sequences:

>Translated_268_residues
MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDN
VGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSAGYSYVIDAIDSVRPKAALIAHCRRNKIPLVTTGGAGGQID
PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGA
ATMVTATFGFVAVSHALKKMMVKAARQG
>Mature_267_residues
SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNV
GLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSAGYSYVIDAIDSVRPKAALIAHCRRNKIPLVTTGGAGGQIDP
TQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGAA
TMVTATFGFVAVSHALKKMMVKAARQG

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=143, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789177, Length=268, Percent_Identity=98.8805970149254, Blast_Score=544, Evalue=1e-156,
Organism=Escherichia coli, GI1787048, Length=131, Percent_Identity=33.587786259542, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082356, Length=136, Percent_Identity=30.8823529411765, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321790, Length=205, Percent_Identity=24.8780487804878, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6322825, Length=202, Percent_Identity=31.1881188118812, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24582879, Length=132, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24660640, Length=137, Percent_Identity=29.9270072992701, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28536; Mature: 28405

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLI
CEEEECHHHHHHHCCEEEHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSA
ECCCEEEECCCCEEEEHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHC
GYSYVIDAIDSVRPKAALIAHCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAK
CHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHH
LRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGA
HHHHHHHHHCCEECCCCCEEEEEEEECCEEEEECCCCCEEEEEECCCCCCCCHHHCCCCH
ATMVTATFGFVAVSHALKKMMVKAARQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLI
EEEECHHHHHHHCCEEEHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSA
ECCCEEEECCCCEEEEHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHC
GYSYVIDAIDSVRPKAALIAHCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAK
CHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHH
LRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGA
HHHHHHHHHCCEECCCCCEEEEEEEECCEEEEECCCCCEEEEEECCCCCCCCHHHCCCCH
ATMVTATFGFVAVSHALKKMMVKAARQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]