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The map label for this gene is fhuA [H]

Identifier: 218547606

GI number: 218547606

Start: 189368

End: 191557

Strand: Direct

Name: fhuA [H]

Synonym: EFER_0173

Alternate gene names: 218547606

Gene position: 189368-191557 (Clockwise)

Preceding gene: 218547605

Following gene: 218547607

Centisome position: 4.13

GC content: 45.62

Gene sequence:

>2190_bases
ATGGCGCGTTCCAAAACTGCTCAGCCAAAACACTCACTGCGTAAAATTGCAGTTGTAGTAGCCACAGCGGTTAGCGGCAT
GTCTGTTTATGCACAGGCAGCGGTTGAACCGAAAGAAGACACTATCACCGTTACCGCTGCACCAGCGCCGCAAGAAAGCG
CATGGGGGCCGGCTGCAACTATTGCGGCGAAGCACTCTGCTACTGCGACTAAAACGGATACACCAATTGAAAAAACGCCG
CAGTCCATTTCGGTTGTGACAAATGAAGAGATGCAGATGCATCAATTTCAGTCTGTAAAAGAAGCATTAGGTTATACACC
TGGTGTTACGGTTAGCAGTCGTGGTGCTTCTAATACATATGATTTTGTTATCATTCGTGGTTTCTCATCTGTTGGTCTGA
ATCAAAATAACTACCTTGATGGGCTAAAACTTCAGGGCAACTTTTATAACGATGCTGTGATTGATCCTTACATGCTCGAG
AGGGTTGAACTGATGCGTGGTCCGACGTCTGTTCTCTATGGGAAAAGTAATCCTGGTGGGATTATTTCTATGGTGAGTAA
GCGTCCGACAACTGAACCCCTGAAAGAAATTCAGTTTAAAATGGGGACGGATAATCTGTTTCAGACCGGATTCGATTTCA
GTGATGCACTGGATGATAACGGTGAGTTCTCCTACCGTTTGACTGGCCTCGCACGCTCAACAAACGAACAGCAGAAAAAC
TCTGAATCTCAGCGTTATACCATTGCTCCATCATTCTCATGGCGTCCGGACAACAAAACTAATTTTACTTTCCTGTCCTA
TTTCCAGAATGAACCTGAAACGGGTTATTACGGTTGGTTGCCGAAAGAGGGGACCGTTGAGCCATTGCCTAATGGTAAGC
GTCTACCGACTGACTTCAATGAAGGTGCGTCGAATAATACATACTCCCGTAACCAGAAAATGGTGGGATATAGTTTTGAA
CATGGTTTTAATGACACCTTCACCGTGCGTCAGAATCTGCGTTTCAGTGAAATGAAAACCTCACAGAAAAGTGTTTATGG
CACAGGGATCGCCGCCGATGGTCATACCCTAAACCGCGGGACAGTGGTGGATAATGAGCGTCTGCAAAACTTTAGCGTTG
ATACCCAACTTGAAAGTAAATTTGCTACAGGTGAAGTCGAGCATACTTTGCTGACAGGGGTTGACTTCATGCGTATGCGC
AATGATATCAATGCCAGCTTTGGATCCGCACCATCCATCGATCTTTATAACAAATATTCTCCTGAATACTTTGCATTTGG
TAGCGCAGAGCCATACCAGATGAATGAAAGCAAACAAACAGGTATTTATGTTCAGGATCAGGCGGAATGGAATAAATGGG
TATTCACTCTAGGGGGACGTTACGATTGGTCTAAGCAAGCGACTACTGTTCGTGAAAACTCTTATACGCCGACTGAAGGT
TATATTGAGCGCAATGATCATCAGTTCACCTGGCGCGGTGGTGTAAATTACTTATTCGATAATGGTATTTCACCTTACTT
TAGCTATAGCCAGTCCTTTGAACCGAGTGCTTTCGATCTATGGAGCAACCCGCGCGTTTCCTATAAGCCATCGAAAGGTG
AACAGTATGAAGCTGGCGTAAAATATGTTCCGAATGATATGCCGGTCGTTGTTACGGGCGCAGTCTATCAATTGACGAAA
ACAAATAACCTGACAGCAGACCCAACAAACCCGTTAGCGCAAGTCCCAGCAGGTGAGATTCGCGCTCGTGGTGTGGAACT
TGAAGCAAAAGCCGCGTTAAATGCCAATATTAACTTGACGGCTTCTTATACTTACACCGATGCGGAATACACCAAAGATA
CTAATCTCAAAGGTAAAACTCCAGAACAAGTACCGGAGCATATGGCATCTCTCTGGGGGGATTATACCTTCAATGAAGGG
CCGCTTTCTGGTTTAACATTGGGAACAGGTGGTCGTTTTATTGGTTCCAGCTATGGTGATCCGACAAACACTTTTAAAGT
GGGTAGCGCAGCTGTAATGGATGCTGTTGTAAAATATGATCTGGCACGCTTTGGTATGGCGGGATCCAGCCTTGCTGTTA
ACGTCAACAATTTGCTCGATCGTGAGTATGTTGCCAGTTGCTTCCAGACCTATGGCTGCTTCTGGGGCGCAGAACGTCAG
GTCGTTGCAACCGCAACCTTCCGTTTCTAA

Upstream 100 bases:

>100_bases
CGTACCGCTTGCGAACCCGCCAGCGTTTCGAATATTATCTCATCTTTATAATAATCATTCTCGTTTACGTTATCATTCAC
TTTACATCAGAGATATACCA

Downstream 100 bases:

>100_bases
TTTCTCTTTTGGGGCACGGATTTCCGTGCCCGTTTCACAAGTTGGCTGTTATGCAGGAATACACGAATCATTCCGATACC
ACTTTTGCACTGCGTAATAT

Product: ferrichrome outer membrane transporter

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAATIAAKHSATATKTDTPIEKTP
QSISVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTYDFVIIRGFSSVGLNQNNYLDGLKLQGNFYNDAVIDPYMLE
RVELMRGPTSVLYGKSNPGGIISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDALDDNGEFSYRLTGLARSTNEQQKN
SESQRYTIAPSFSWRPDNKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGASNNTYSRNQKMVGYSFE
HGFNDTFTVRQNLRFSEMKTSQKSVYGTGIAADGHTLNRGTVVDNERLQNFSVDTQLESKFATGEVEHTLLTGVDFMRMR
NDINASFGSAPSIDLYNKYSPEYFAFGSAEPYQMNESKQTGIYVQDQAEWNKWVFTLGGRYDWSKQATTVRENSYTPTEG
YIERNDHQFTWRGGVNYLFDNGISPYFSYSQSFEPSAFDLWSNPRVSYKPSKGEQYEAGVKYVPNDMPVVVTGAVYQLTK
TNNLTADPTNPLAQVPAGEIRARGVELEAKAALNANINLTASYTYTDAEYTKDTNLKGKTPEQVPEHMASLWGDYTFNEG
PLSGLTLGTGGRFIGSSYGDPTNTFKVGSAAVMDAVVKYDLARFGMAGSSLAVNVNNLLDREYVASCFQTYGCFWGAERQ
VVATATFRF

Sequences:

>Translated_729_residues
MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAATIAAKHSATATKTDTPIEKTP
QSISVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTYDFVIIRGFSSVGLNQNNYLDGLKLQGNFYNDAVIDPYMLE
RVELMRGPTSVLYGKSNPGGIISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDALDDNGEFSYRLTGLARSTNEQQKN
SESQRYTIAPSFSWRPDNKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGASNNTYSRNQKMVGYSFE
HGFNDTFTVRQNLRFSEMKTSQKSVYGTGIAADGHTLNRGTVVDNERLQNFSVDTQLESKFATGEVEHTLLTGVDFMRMR
NDINASFGSAPSIDLYNKYSPEYFAFGSAEPYQMNESKQTGIYVQDQAEWNKWVFTLGGRYDWSKQATTVRENSYTPTEG
YIERNDHQFTWRGGVNYLFDNGISPYFSYSQSFEPSAFDLWSNPRVSYKPSKGEQYEAGVKYVPNDMPVVVTGAVYQLTK
TNNLTADPTNPLAQVPAGEIRARGVELEAKAALNANINLTASYTYTDAEYTKDTNLKGKTPEQVPEHMASLWGDYTFNEG
PLSGLTLGTGGRFIGSSYGDPTNTFKVGSAAVMDAVVKYDLARFGMAGSSLAVNVNNLLDREYVASCFQTYGCFWGAERQ
VVATATFRF
>Mature_728_residues
ARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAATIAAKHSATATKTDTPIEKTPQ
SISVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTYDFVIIRGFSSVGLNQNNYLDGLKLQGNFYNDAVIDPYMLER
VELMRGPTSVLYGKSNPGGIISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDALDDNGEFSYRLTGLARSTNEQQKNS
ESQRYTIAPSFSWRPDNKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGASNNTYSRNQKMVGYSFEH
GFNDTFTVRQNLRFSEMKTSQKSVYGTGIAADGHTLNRGTVVDNERLQNFSVDTQLESKFATGEVEHTLLTGVDFMRMRN
DINASFGSAPSIDLYNKYSPEYFAFGSAEPYQMNESKQTGIYVQDQAEWNKWVFTLGGRYDWSKQATTVRENSYTPTEGY
IERNDHQFTWRGGVNYLFDNGISPYFSYSQSFEPSAFDLWSNPRVSYKPSKGEQYEAGVKYVPNDMPVVVTGAVYQLTKT
NNLTADPTNPLAQVPAGEIRARGVELEAKAALNANINLTASYTYTDAEYTKDTNLKGKTPEQVPEHMASLWGDYTFNEGP
LSGLTLGTGGRFIGSSYGDPTNTFKVGSAAVMDAVVKYDLARFGMAGSSLAVNVNNLLDREYVASCFQTYGCFWGAERQV
VATATFRF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=754, Percent_Identity=73.6074270557029, Blast_Score=1112, Evalue=0.0,
Organism=Escherichia coli, GI1787024, Length=806, Percent_Identity=24.317617866005, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1787344, Length=792, Percent_Identity=22.6010101010101, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787723, Length=729, Percent_Identity=22.3593964334705, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788478, Length=132, Percent_Identity=29.5454545454545, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80768; Mature: 80637

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAAT
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEHCCCCCCCCEEEEEECCCCCCCCCCCCEE
IAAKHSATATKTDTPIEKTPQSISVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTY
EEECCCCCCCCCCCCHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCE
DFVIIRGFSSVGLNQNNYLDGLKLQGNFYNDAVIDPYMLERVELMRGPTSVLYGKSNPGG
EEEEEECCHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
IISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDALDDNGEFSYRLTGLARSTNEQQKN
EEEEECCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHCCCCCCEEEEEEEEHHCCCHHHHC
SESQRYTIAPSFSWRPDNKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFN
CCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
EGASNNTYSRNQKMVGYSFEHGFNDTFTVRQNLRFSEMKTSQKSVYGTGIAADGHTLNRG
CCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHCCHHHHEECEEECCCCCCCCC
TVVDNERLQNFSVDTQLESKFATGEVEHTLLTGVDFMRMRNDINASFGSAPSIDLYNKYS
EEECCHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCC
PEYFAFGSAEPYQMNESKQTGIYVQDQAEWNKWVFTLGGRYDWSKQATTVRENSYTPTEG
CCEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCC
YIERNDHQFTWRGGVNYLFDNGISPYFSYSQSFEPSAFDLWSNPRVSYKPSKGEQYEAGV
CEECCCCEEEEECCCCEEECCCCCHHHCCCCCCCCCCEECCCCCCEEECCCCCCCCCCCC
KYVPNDMPVVVTGAVYQLTKTNNLTADPTNPLAQVPAGEIRARGVELEAKAALNANINLT
EECCCCCCEEEECEEEEEEECCCCCCCCCCCHHHCCCCHHEECCEEEEEEEEECCCEEEE
ASYTYTDAEYTKDTNLKGKTPEQVPEHMASLWGDYTFNEGPLSGLTLGTGGRFIGSSYGD
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCC
PTNTFKVGSAAVMDAVVKYDLARFGMAGSSLAVNVNNLLDREYVASCFQTYGCFWGAERQ
CCCEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCE
VVATATFRF
EEEEEEECC
>Mature Secondary Structure 
ARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAAT
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEHCCCCCCCCEEEEEECCCCCCCCCCCCEE
IAAKHSATATKTDTPIEKTPQSISVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTY
EEECCCCCCCCCCCCHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCE
DFVIIRGFSSVGLNQNNYLDGLKLQGNFYNDAVIDPYMLERVELMRGPTSVLYGKSNPGG
EEEEEECCHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
IISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDALDDNGEFSYRLTGLARSTNEQQKN
EEEEECCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHCCCCCCEEEEEEEEHHCCCHHHHC
SESQRYTIAPSFSWRPDNKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFN
CCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
EGASNNTYSRNQKMVGYSFEHGFNDTFTVRQNLRFSEMKTSQKSVYGTGIAADGHTLNRG
CCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHCCHHHHEECEEECCCCCCCCC
TVVDNERLQNFSVDTQLESKFATGEVEHTLLTGVDFMRMRNDINASFGSAPSIDLYNKYS
EEECCHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCC
PEYFAFGSAEPYQMNESKQTGIYVQDQAEWNKWVFTLGGRYDWSKQATTVRENSYTPTEG
CCEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCC
YIERNDHQFTWRGGVNYLFDNGISPYFSYSQSFEPSAFDLWSNPRVSYKPSKGEQYEAGV
CEECCCCEEEEECCCCEEECCCCCHHHCCCCCCCCCCEECCCCCCEEECCCCCCCCCCCC
KYVPNDMPVVVTGAVYQLTKTNNLTADPTNPLAQVPAGEIRARGVELEAKAALNANINLT
EECCCCCCEEEECEEEEEEECCCCCCCCCCCHHHCCCCHHEECCEEEEEEEEECCCEEEE
ASYTYTDAEYTKDTNLKGKTPEQVPEHMASLWGDYTFNEGPLSGLTLGTGGRFIGSSYGD
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCC
PTNTFKVGSAAVMDAVVKYDLARFGMAGSSLAVNVNNLLDREYVASCFQTYGCFWGAERQ
CCCEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCE
VVATATFRF
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]