| Definition | Escherichia fergusonii ATCC 35469 chromosome, complete genome. |
|---|---|
| Accession | NC_011740 |
| Length | 4,588,711 |
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The map label for this gene is gcd [H]
Identifier: 218547580
GI number: 218547580
Start: 160496
End: 162886
Strand: Reverse
Name: gcd [H]
Synonym: EFER_0145
Alternate gene names: 218547580
Gene position: 162886-160496 (Counterclockwise)
Preceding gene: 218547582
Following gene: 218547578
Centisome position: 3.55
GC content: 54.71
Gene sequence:
>2391_bases ATGGCAATTAACAATACCGGCTCGCGACGATTACTCGTCACGCTAACAGCCCTATTTGCAGCGCTTTGCGGGCTGTATCT TCTCATTGGCGGAGGCTGGTTGGTCGCGATCGGCGGCTCCTGGTACTACCCTATCGCTGGCCTTATGATGCTCGGCGTCG CCTGGATGCTGTGGCGCAGCAAACGCGCCGCACTTTGGCTTTACGCGGCATTGCTGCTTGGCACCATGATTTGGGGCGTC TGGGAAGTGGGTTTCGATTTCTGGGCGCTGACGCCGCGTAGCGACATTCTGGTCTTCTTTGGTATCTGGCTGATCCTGCC GTTTGTCTGGCGTCGCCTGGTCATTCCTGCCAGCGGCGCAGTTGCCGCGTTGGTGGTCGCGCTGTTGATTAGCGGTGGTA TCCTCACCTGGGCCGGATTTAACGATCCACAGGAAATCAACGGCACCTTAAGCGCTGATGCTACACCTGCCGAAGCTATC TCCCCCGTTGCCGATCAAGACTGGCCTGCCTATGGTCGCAATCAGGAAGGTCAACGCTTTTCACCACTGAAACAAATTAA CGCTGATAACGTCCACAAGCTGAAAGAAGCCTGGGTGTTCCGTACAGGCGATGTGAAACAGCCGAACGATCCGGGCGAAA TCACCAATGAAGTGACGCCGATTAAAGTAGGCGACACGCTTTACCTGTGTACCGCTCACCAGCGTTTGTTTGCGCTCGAT GCCGCCAGCGGCAAAGAGAAATGGCATTACGATCCTGAGCTGAAAACCAACGAGTCTTTCCAGCATGTAACCTGCCGTGG TGTCTCTTATCATGAAGCCAAAGCAGAAACTGCTTCGCCGGAAGTGATGGCGGATTGCCCGCGTCGTATCATTCTCCCAG TCAATGATGGCCGCCTGATTGCGATTAACGCTGAAAACGGCAAGCTGTGCGAAACCTTCGCCAATAAAGGCGTGCTCAAC CTGCAAAGCAACATGCCGGACACCAAACCGGGCCTGTATGAGCCGACTTCACCACCGATTATCACTGATAAAACCATCGT GATGGCGGGTTCCGTCACTGATAACTTCTCAACCCGCGAAACGTCTGGCGTGATCCGTGGTTTTGATGTCAATACCGGGG AGCTGTTGTGGGCCTTTGATCCAGGCGCGAAAGATCCGAACGCGATCCCGTCTGACGAACACACCTTTACCTTTAACTCG CCAAACTCGTGGGCACCTGCGGCCTATGACGCGAAGCTGGATCTGGTGTATCTGCCGATGGGCGTTACCACGCCAGATAT CTGGGGCGGTAACCGCACCCCAGAACAGGAACGTTATGCCAGCTCGATTCTGGCGCTGAATGCCACTACCGGGAAACTGG CGTGGAGCTATCAGACCGTTCACCACGACCTGTGGGATATGGATCTTCCGGCACAGCCAACGCTGGCAGATATCACCGTT AATGGTCAAAAAGTTCCGGTTATTTACGCTCCAGCGAAAACCGGCAACATTTTTGTGCTTGATCGCCGCAATGGTGAACT GGTGGTTCCGGCCCCGGAAAAACCAGTTCCCCAAGGCGCAGCGAAAGGTGATTACGTTACCCCTACTCAACCGTTCTCTG AACTGAGCTTCCGTCCGAAGAAAGATTTGAGCGGTGCGGATATGTGGGGCGCCACCATGTTTGACCAACTGGTGTGCCGC GTGATGTTCCACCAGATGCGCTATGAAGGTATTTTCACGCCGCCATCTGAACAGGGTACGCTGGTCTTCCCGGGTAACCT GGGGATGTTCGAATGGGGCGGGATTTCCGTTGATCCGAATCGTGAAGTGGCAATTGCCAACCCAATGGCACTGCCGTTTG TTTCGAAACTGATCCCTCGCGGTCCTGGCAACCCGATGGAACAGCCAAAAGATGCCAAAGGCACCGGTACGGAATCCGGC ATTCAGCCGCAGTACGGCGTACCGTATGGCGTTACGCTTAACCCGTTCCTTTCACCATTTGGTCTGCCATGTAAACAGCC AGCATGGGGTTATATTTCGGCGCTGGATCTGAAAACCAATGAAGTGGTGTGGAAGAAACGCATTGGTACGCCGCAGGACA GCATGCCGTTCCCGATGCCGGTTCCTGTGCCGTTCAATATGGGTATGCCGATGCTGGGCGGGCCAATCTCCACGGCGGGT AACGTGCTGTTTATCGCCGCTACGGCAGATAACTACCTGCGCGCTTACAACATGAGCAACGGTGAAAAACTGTGGCAGGG CCGTTTACCGGCGGGTGGTCAGGCAACACCGATGACCTATGAAGTGAATGGCAAGCAATATGTGGTGATATCCGCAGGCG GTCACGGTTCATTTGGTACGAAGATGGGCGACTATATTGTGGCTTATGCGTTGCCGGATGATGTGAAATAA
Upstream 100 bases:
>100_bases GAATCTGTTAATAAAGCTCGAATTGTGATGACGATCACACATGTTAAAACCTATAATTAATTGCTACTAAAATATTAATG AATTGAAATGGTGTCTCTTT
Downstream 100 bases:
>100_bases CCATAATGCCCGGAGAGATCCGGGCATATTTCCAAATACGGTCTTTTTATACCGTAAACCCTAACATCATCCCCGTATCT TCATGCTCCAGCAGATGGCA
Product: glucose dehydrogenase
Products: NA
Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]
Number of amino acids: Translated: 796; Mature: 795
Protein sequence:
>796_residues MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLMMLGVAWMLWRSKRAALWLYAALLLGTMIWGV WEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAI SPVADQDWPAYGRNQEGQRFSPLKQINADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLN LQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNS PNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV NGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPKKDLSGADMWGATMFDQLVCR VMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESG IQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
Sequences:
>Translated_796_residues MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLMMLGVAWMLWRSKRAALWLYAALLLGTMIWGV WEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAI SPVADQDWPAYGRNQEGQRFSPLKQINADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLN LQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNS PNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV NGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPKKDLSGADMWGATMFDQLVCR VMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESG IQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK >Mature_795_residues AINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLMMLGVAWMLWRSKRAALWLYAALLLGTMIWGVW EVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAIS PVADQDWPAYGRNQEGQRFSPLKQINADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALDA ASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNL QSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSP NSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITVN GQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPKKDLSGADMWGATMFDQLVCRV MFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGI QPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGN VLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
Specific function: GDH is probably involved in energy conservation rather than in sugar metabolism [H]
COG id: COG4993
COG function: function code G; Glucose dehydrogenase
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]
Homologues:
Organism=Escherichia coli, GI1786316, Length=796, Percent_Identity=99.6231155778894, Blast_Score=1626, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017511 - InterPro: IPR019556 - InterPro: IPR019551 - InterPro: IPR018391 - InterPro: IPR002372 - InterPro: IPR011047 - InterPro: IPR001479 [H]
Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]
EC number: =1.1.5.2 [H]
Molecular weight: Translated: 86821; Mature: 86690
Theoretical pI: Translated: 5.55; Mature: 5.55
Prosite motif: PS00363 BACTERIAL_PQQ_1 ; PS00364 BACTERIAL_PQQ_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLMMLGVAWMLWRS CCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC KRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGA CCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCH VAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAISPVADQDWPAYGRNQEGQRF HHHHHHHHHHCCCEEEECCCCCHHHCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCC SPLKQINADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD CHHHHCCCCHHHHHHHHHEEECCCCCCCCCCCHHCCCCCEEEECCEEEEEECCCEEEEEE AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLI CCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCCCCCHHHHCCCCEEEEEECCCEEE AINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRE EEECCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCCCCC TSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPM CCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEECCEEEEEEEEC GVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV CCCCCCCCCCCCCCHHHHHHHEEEEEECCCCCEEEEEEHHHHHHHCCCCCCCCCEEEEEE NGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPK CCCEEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCC KDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPN CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEECCCCCEEECCCEEECCC REVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPF CCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG CCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGT CEEEEEECCCCEEEEECCCCCHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCC KMGDYIVAYALPDDVK CCCCEEEEEECCCCCC >Mature Secondary Structure AINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLMMLGVAWMLWRS CCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC KRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGA CCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCH VAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAISPVADQDWPAYGRNQEGQRF HHHHHHHHHHCCCEEEECCCCCHHHCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCC SPLKQINADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD CHHHHCCCCHHHHHHHHHEEECCCCCCCCCCCHHCCCCCEEEECCEEEEEECCCEEEEEE AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLI CCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCCCCCHHHHCCCCEEEEEECCCEEE AINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRE EEECCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCCCCC TSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPM CCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEECCEEEEEEEEC GVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV CCCCCCCCCCCCCCHHHHHHHEEEEEECCCCCEEEEEEHHHHHHHCCCCCCCCCEEEEEE NGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPK CCCEEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCC KDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPN CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEECCCCCEEECCCEEECCC REVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPF CCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG CCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGT CEEEEEECCCCEEEEECCCCCHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCC KMGDYIVAYALPDDVK CCCCEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 2228962; 8419307; 8202364; 9278503; 8509415; 8554505 [H]