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The map label for this gene is sgrR [H]

Identifier: 218547522

GI number: 218547522

Start: 89974

End: 91629

Strand: Reverse

Name: sgrR [H]

Synonym: EFER_0083

Alternate gene names: 218547522

Gene position: 91629-89974 (Counterclockwise)

Preceding gene: 218547525

Following gene: 218547521

Centisome position: 2.0

GC content: 55.31

Gene sequence:

>1656_bases
ATGCCTTCCTCTCGTTTGCAACAGCAGTTCATCCGTTTGTGGCAATGCTGCGACGGTAAATCTCAGGAGACCACGCTGAA
CGAACTGGCGGAGTTGCTCAACTGTTCCCGTCGCCATATGCGCACGCTCCTGAATACCATGCAGGAGCGTGGCTGGTTGA
CGTGGGAAGCGGAAGTCGGTCGCGGTAAGCGTTCACGCCTGACATTCCTCTATACCGGGCTGGCGCTCCAGCAACAACGT
GCGGAAGATTTACTTGAGCAGGACCATATAGACCAACTGGTGCAGTTGGTTGGCGACAAAGCAGCTGTGCGGAAAATGCT
GGTTTCTCATCTGGGGCGTAGCTTCCGCCAGGGGCGACATATCCTGCGCGTGCTCTACTATCGTCCGTTGCGTAATCTGC
TGCCCGGCAGCGCATTGCGCCGTTCCGAAACGCATATTGCCCGGCAAATTTTCAGTTCGCTAACGCGCGTAAATGAGGAA
AATGGGGAACTGGAGGCGGACATCGCCCACCACTGGCAGCAAATTTCACCGCTTCACTGGCGCTTCTTTTTACGTCCAGG
AGTCCATTTTCATCATGGTCGTGAACTGGAAATGGACGACGTGATAGCCTCTTTGAAACGGATCAATACGCTGCCGCTCT
ATTCGCATATTGCTGAAATTGTGTCGCCGACGCCCTGGACGCTGGACATCCATCTCACGCAGCCAGACCGCTGGTTGCCG
TTACTGCTGGGGCAAGTTCCGGCGATGATCCTGCCGCGCGAATGGGAAACCCTCAGTAACTTTGCCAGCCATCCCATCGG
CACCGGTCCGTATGCGGTGCTCCGCAACAGCAGCAATCAACTGAAAATTCAGGCATTCGATGACTTCTTCGGTTATCGCG
CATTAATCGACGAAGTAAACGTCTGGGTTCTGCCGGAAAGTGCCGACGAGCCAGCCTGTGGACTGATGCTTGAAGGGCCT
CAGGGCGAGGAAAAAGAGATTGAAAGCCGCCTGGAGGAAGGTTGCTATTATTTACTGTTCGACAGCCGCACCCATCGTGG
GGCGAATCAGGCGGTAAGAGACTGGGTAAGCTATGTTCTCTCCCCCACCAACCTGGTCTATTTTGCCGAAGAGCAGTACC
AGCAACTGTGGTTTCCGGCCTACGGTCTGCTGCCGCGCTGGCACCATGCCCATATCCTACAGAGCGAAAAACCTGCCGGA
CTGGAAAGCCTCACCCTGACCTTTTATCAGGATCATAGTGAGCATCGGGTGATTGCCAGGATCATGCAGCAGATTCTGGC
AAGTCACCAGGTCACGCTGGAAATCAAAGAGATCAGCTACGATCAGTGGCACGAAGGAGAGATCGAAAGCGACATCTGGC
TTAACAGCGCCAACTTTACGCTGCCGCTGGATTTTTCGCTGTTCGCGCATTTGTGCGAAGTGCCGCTGCTACAACACTGT
ATTCCGATCGACTGGCAAGCCGACGCCGCCCGCTGGCGCAATGGCGAAATGAACCTGGCGAACTGGTGCCAGCAACTGGT
CGCCAGCAAAGCAATGGTGCCGCTCATCCACCACTGGCTGATCATTCAGGGGCAACGCAGTATGCGCGGCCTGCGCATGA
ACACTCTCGGCTGGTTCGATTTTAAATCCGCGTGGTTTGCACCACCGGATCCATGA

Upstream 100 bases:

>100_bases
AAACTGATGCATATCCCACCTCCTCGCTTCATCGACAGTGATTATTGGCCTAATATAGGGATTATTAAATTGCTGGATTT
TCCCCAGGAGTTCCCCTTTT

Downstream 100 bases:

>100_bases
TTGCTGGTTGATAACAAAATCACTACACTAACGCCGTTCTCAACGGGGTGCCACGCAGACGCGTGCGCTGAGAAAATACC
CGTCGAACCTGATCCGGATA

Product: transcriptional regulator SgrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MPSSRLQQQFIRLWQCCDGKSQETTLNELAELLNCSRRHMRTLLNTMQERGWLTWEAEVGRGKRSRLTFLYTGLALQQQR
AEDLLEQDHIDQLVQLVGDKAAVRKMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRVNEE
NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLP
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVLRNSSNQLKIQAFDDFFGYRALIDEVNVWVLPESADEPACGLMLEGP
QGEEKEIESRLEEGCYYLLFDSRTHRGANQAVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHAHILQSEKPAG
LESLTLTFYQDHSEHRVIARIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
IPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP

Sequences:

>Translated_551_residues
MPSSRLQQQFIRLWQCCDGKSQETTLNELAELLNCSRRHMRTLLNTMQERGWLTWEAEVGRGKRSRLTFLYTGLALQQQR
AEDLLEQDHIDQLVQLVGDKAAVRKMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRVNEE
NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLP
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVLRNSSNQLKIQAFDDFFGYRALIDEVNVWVLPESADEPACGLMLEGP
QGEEKEIESRLEEGCYYLLFDSRTHRGANQAVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHAHILQSEKPAG
LESLTLTFYQDHSEHRVIARIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
IPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP
>Mature_550_residues
PSSRLQQQFIRLWQCCDGKSQETTLNELAELLNCSRRHMRTLLNTMQERGWLTWEAEVGRGKRSRLTFLYTGLALQQQRA
EDLLEQDHIDQLVQLVGDKAAVRKMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRVNEEN
GELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLPL
LLGQVPAMILPREWETLSNFASHPIGTGPYAVLRNSSNQLKIQAFDDFFGYRALIDEVNVWVLPESADEPACGLMLEGPQ
GEEKEIESRLEEGCYYLLFDSRTHRGANQAVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHAHILQSEKPAGL
ESLTLTFYQDHSEHRVIARIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCI
PIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=551, Percent_Identity=95.0998185117967, Blast_Score=1092, Evalue=0.0,
Organism=Escherichia coli, GI1786650, Length=591, Percent_Identity=27.580372250423, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64099; Mature: 63968

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSRLQQQFIRLWQCCDGKSQETTLNELAELLNCSRRHMRTLLNTMQERGWLTWEAEVG
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RGKRSRLTFLYTGLALQQQRAEDLLEQDHIDQLVQLVGDKAAVRKMLVSHLGRSFRQGRH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRVNEENGELEADIAHHWQQISPLHW
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEE
RFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLP
EEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHH
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVLRNSSNQLKIQAFDDFFGYRALIDEVN
HHHHCCCHHCCCCHHHHHHHHHCCCCCCCCHHEEECCCCEEEEEEEHHHHHHHHHHHCCC
VWVLPESADEPACGLMLEGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQAVRDWVSYVL
EEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
SPTNLVYFAEEQYQQLWFPAYGLLPRWHHAHILQSEKPAGLESLTLTFYQDHSEHRVIAR
CCCCEEEEEHHHHHHHHCCHHHCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
IMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHC
IPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFD
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEECCCCCCC
FKSAWFAPPDP
CCCCCCCCCCC
>Mature Secondary Structure 
PSSRLQQQFIRLWQCCDGKSQETTLNELAELLNCSRRHMRTLLNTMQERGWLTWEAEVG
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RGKRSRLTFLYTGLALQQQRAEDLLEQDHIDQLVQLVGDKAAVRKMLVSHLGRSFRQGRH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRVNEENGELEADIAHHWQQISPLHW
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEE
RFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLP
EEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHH
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVLRNSSNQLKIQAFDDFFGYRALIDEVN
HHHHCCCHHCCCCHHHHHHHHHCCCCCCCCHHEEECCCCEEEEEEEHHHHHHHHHHHCCC
VWVLPESADEPACGLMLEGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQAVRDWVSYVL
EEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
SPTNLVYFAEEQYQQLWFPAYGLLPRWHHAHILQSEKPAGLESLTLTFYQDHSEHRVIAR
CCCCEEEEEHHHHHHHHCCHHHCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
IMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHC
IPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFD
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEECCCCCCC
FKSAWFAPPDP
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]