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The map label for this gene is yaaU [H]

Identifier: 218547492

GI number: 218547492

Start: 54979

End: 56310

Strand: Direct

Name: yaaU [H]

Synonym: EFER_0053

Alternate gene names: 218547492

Gene position: 54979-56310 (Clockwise)

Preceding gene: 218547491

Following gene: 218547493

Centisome position: 1.2

GC content: 53.83

Gene sequence:

>1332_bases
ATGCAACCGTCCAGAAACTTTGACGATCTCAAATTCTCCTCAATTCACCGCCGCATTTTGCTGTGGGGAAGCGGTGGCCC
GTTTCTGGATGGTTATGTACTGGTAATGATTGGCGTGGCGCTGGAGCAACTGACTCCTGCGCTGAAGCTGGACGCAGACT
GGATTGGCTTGCTGGGGGCGGGAACGCTCGCCGGGCTGTTTGTCGGTACATCGCTGTTTGGCTATATCTCCGATAAGGTC
GGACGGCGCAAAATGTTCCTCATTGATATCATCGCCATCGGTGTGATATCGGTAGCAACGATGTTTGTCTCATCCCCCAT
CGAACTACTGGTGATGCGGGTACTCATCGGCATTGTCATCGGTGCGGATTATCCCATCGCGACTTCGATGATCACCGAGT
TCTCCAGCACCCGTCAGCGGGCGTTTTCCATCAGCTTTATCGCCGCTATGTGGTATGTCGGCGCGACCTGTGCCGATCTG
GTCGGCTACTGGCTTTATGATGTGGAAGGCGGCTGGCGCTGGATGCTGGGTAGCGCGGCGATCCCCTGTTTGTTGATTTT
GATTGGTCGATTCGAACTGCCAGAATCTCCCCGCTGGTTATTACGCAAGGGGCGAGTGAAAGAGTGCGAAGAGATGATGA
TCAAACTGTTTGGTGAGCCGGTGGCTTTCGACGAAGAGCCGCCGCAGCAAGCCCGTTTTCGCGATCTGTTTAATCGCCGC
CATTTTCCTTTTGTTCTGTTTGTTGCCGCCATCTGGACCTGCCAGGTGATCCCGATGTTCGCTATTTACACCTTTGGCCC
GCAAATTGTTGGTTTGTTGGGATTGGGGGTTGGCAAAAACGCGGCGCTGGGGAACGTGGTGATTAGCCTGTTCTTTATGC
TCGGCTGTATTCCGCCGATGCTGTGGCTAAACACTGCCGGACGGCGTCCGTTGTTGATTGGCAGCTTTGCCATGATGACG
CTGGCGTTGGCGGTTTTGGGGCTGATCCCGGATATGGGGATCTGGCTGGTAGTGATGGCATTTGCGGTGTATGCCTTTTT
CTCTGGTGGGCCGGGTAATTTGCAGTGGCTCTATCCTAATGAACTCTTCCCGACGGATATCCGCGCCTCTGCTGTGGGCG
TTATTATGTCCTTAAGCCGTATTGGCACCATTGTTTCAACCTGGGCGCTGCCGATCTTTATCAATAATTACGGCATCAGT
AACACGATGCTGATGGGAGCAGGTATCTCGCTGTTTGGTTTGTTGATTTCCATTGCGTTTGCGCCAGAGACACGGGGGAT
GTCGCTGGCCCAGACCAGCAATATGACGATTCGCAGGCAACGAATGGGGTAA

Upstream 100 bases:

>100_bases
TACCCGCGCGGCACCTTTGGTGTGGAGTTTCGTTACGGTTGATGTTGGTTTGATACGTAACGCCGTACTGACTCTCATTG
TAAAAAAACAGGAATAACCC

Downstream 100 bases:

>100_bases
TTTATTCAGATTTCTGCCTTTTTTGAATCAATATTATTGACTATTAGCTGCGTGAATATGTGACTACACTTTGTGGGAAA
ACAAAGGCGTAAACACGCGA

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPIELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEPPQQARFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISIAFAPETRGMSLAQTSNMTIRRQRMG

Sequences:

>Translated_443_residues
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPIELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEPPQQARFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISIAFAPETRGMSLAQTSNMTIRRQRMG
>Mature_443_residues
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPIELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEPPQQARFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISIAFAPETRGMSLAQTSNMTIRRQRMG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24497497, Length=387, Percent_Identity=26.8733850129199, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI90669191, Length=387, Percent_Identity=26.8733850129199, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI24308167, Length=440, Percent_Identity=22.0454545454545, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI31542327, Length=434, Percent_Identity=25.1152073732719, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI24497490, Length=391, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI166064021, Length=382, Percent_Identity=24.3455497382199, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4507005, Length=408, Percent_Identity=22.7941176470588, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI166197673, Length=366, Percent_Identity=24.5901639344262, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI302148518, Length=425, Percent_Identity=23.0588235294118, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4506999, Length=439, Percent_Identity=23.9179954441913, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI203098995, Length=223, Percent_Identity=28.2511210762332, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI216548223, Length=166, Percent_Identity=29.5180722891566, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI21553331, Length=313, Percent_Identity=21.7252396166134, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI7662270, Length=192, Percent_Identity=25.5208333333333, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI23510410, Length=189, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI73695465, Length=166, Percent_Identity=29.5180722891566, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786229, Length=443, Percent_Identity=98.8713318284424, Blast_Score=875, Evalue=0.0,
Organism=Escherichia coli, GI87082159, Length=431, Percent_Identity=34.338747099768, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789312, Length=402, Percent_Identity=25.3731343283582, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789207, Length=392, Percent_Identity=25.765306122449, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790463, Length=425, Percent_Identity=24, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788074, Length=427, Percent_Identity=24.3559718969555, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788068, Length=462, Percent_Identity=24.8917748917749, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17565976, Length=332, Percent_Identity=26.2048192771084, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17565978, Length=332, Percent_Identity=24.0963855421687, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32564663, Length=406, Percent_Identity=22.4137931034483, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71986689, Length=442, Percent_Identity=24.6606334841629, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193202825, Length=442, Percent_Identity=24.6606334841629, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71980582, Length=426, Percent_Identity=23.943661971831, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71980584, Length=426, Percent_Identity=23.943661971831, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17543784, Length=394, Percent_Identity=26.1421319796954, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193209824, Length=400, Percent_Identity=23, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71986504, Length=427, Percent_Identity=23.1850117096019, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323512, Length=458, Percent_Identity=22.9257641921397, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321068, Length=429, Percent_Identity=22.3776223776224, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573193, Length=368, Percent_Identity=26.9021739130435, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24644782, Length=368, Percent_Identity=26.6304347826087, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI62484254, Length=375, Percent_Identity=24, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24668456, Length=397, Percent_Identity=21.9143576826196, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19922616, Length=389, Percent_Identity=24.4215938303342, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644778, Length=450, Percent_Identity=24.2222222222222, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221330907, Length=341, Percent_Identity=24.9266862170088, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24668440, Length=399, Percent_Identity=23.5588972431078, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24652795, Length=423, Percent_Identity=23.8770685579196, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649616, Length=355, Percent_Identity=23.943661971831, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652793, Length=423, Percent_Identity=23.8770685579196, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649618, Length=354, Percent_Identity=22.316384180791, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24658792, Length=400, Percent_Identity=24, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221457681, Length=431, Percent_Identity=23.8979118329466, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640198, Length=171, Percent_Identity=28.0701754385965, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640196, Length=171, Percent_Identity=28.0701754385965, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640200, Length=171, Percent_Identity=28.0701754385965, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161078612, Length=436, Percent_Identity=22.4770642201835, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 48734; Mature: 48734

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGA
CCCCCCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHH
GTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPIELLVMRVLIGIVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHH
IPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEPPQQARFRDLFNRR
HHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPM
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPN
HHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
ELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISIAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCHHHHHHHHHHHC
APETRGMSLAQTSNMTIRRQRMG
CCCCCCCEEEECCCCEEEHHCCC
>Mature Secondary Structure
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGA
CCCCCCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHH
GTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPIELLVMRVLIGIVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHH
IPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEPPQQARFRDLFNRR
HHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPM
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPN
HHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
ELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISIAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCHHHHHHHHHHHC
APETRGMSLAQTSNMTIRRQRMG
CCCCCCCEEEECCCCEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]