Click here to switch to the map view.

The map label for this gene is ttuB [H]

Identifier: 218533218

GI number: 218533218

Start: 5729567

End: 5730901

Strand: Reverse

Name: ttuB [H]

Synonym: Mchl_5346

Alternate gene names: 218533218

Gene position: 5730901-5729567 (Counterclockwise)

Preceding gene: 218533222

Following gene: 218533217

Centisome position: 99.19

GC content: 70.11

Gene sequence:

>1335_bases
ATGGCGGATGCGCTCACGAGCAAGGTGGCGCGGCGCCTGCTGCCCTTCCTGATGCTGTGCTACTTCTTCGCCTATCTCGA
CCGGGTGAATGTCGGCTTCGCCGCACTCACCATGAACCGGGATCTCGGCCTGTCGGCGACGGCCTACGGGTTCGGGGCGG
GTCTGTTCTTTCTCGGCTACGTCGCCTTCGAGGTGCCGAGCAACCTGATCCTGGAGCGGGTCGGGGCGCGGCTCTGGATC
GCGCGGATCATGGTGACCTGGTCGCTGGTTTCGGCCTCGACTGCGCTCGTCGTCGGCGAATGGTCGTTCTACCTCGTGCG
CATCGGGCTCGGGCTCGCCGAAGCCGGCTTCTTCCCCGGCATCATCCTCTATCTCACCTACTGGTTTCCCGCCCGGCAGC
GCGCCGGCATCGTCGGCACCTTCATGATGGCGGTGCCGCTCTCGGCAGCGATCGGTGCGCCGCTCTCGGGCCTCGTCATG
AGCCTCACCGACGGCTGGCTCGGGCTCGCGGGCTGGCAGTGGCTTTACCTGCTGGAAGCCGCACCCAGCCTGCTTCTCGG
CATCGCGACCCTGTTCGTGCTGACCGACCGGCCGGAACGCGCCTCGTGGCTGACCGCCGAGGAGCGGGCGAGCCTCGTGG
CGCGGATGGCGGAGGATCGCCGGCTCAGCCCGAACCGGACGGCGCATCTGGGTGCAGCCCTGCTCGACCCGCGGGTGCTC
GGGCTCGGGCTGGTCTATTTCGGGCTCAGCACCGGACTCTACGCCGTCGGCCTGTGGTTACCGCAGATCGTGAGCGGCTT
CGGCTTCACGACGACGGCGACGGGGTTCGTGACCGCCGTGCCCTACATCGTCTCCGCTGCGGGCATGCTGCTCTGGACGC
GCCATTCCGACCGCACGGGTGAGCGCACCCGCCATGTCGCGATCCCGACGGTGGCCGCCGGCCTCGCCCTCTTCGCCGCG
AGCCGGGCCGGCACACCGCTCCTGACCATCGCCGCGCTCAGTGCGGTGGCGCTCGGCGTTTTCGCGGCTCTGCCGACCTT
CTGGACATTGCCCACCCGCCTCCTCACGGGCAGCGCGGCCGCGGGCGGCATCGCCCTGATCAACGCGCTCGGAAGCCTCG
GCGGATTTGCCGGACCCGCCCTCATGGGCTGGATCCGCGATGCGACCGGCCGCTTCGACGACGCGTTGGCGGCGGTGGCC
GCCGTGCTGGTTGTGGCAGGGCTCGCGGTTCTTCGTCTCGGCCGGGACATCGCGCGGGATACGGGCGCGAGCGCGGATGC
CGGACCGGCCCGAAGCCCCGAGGGAGACGCTCGACCGGCGCCAAATCAGCAATGA

Upstream 100 bases:

>100_bases
CCGTGGCGGGGCCTGAAGCCGCTTCTATCCGGCCCTCGGCAAGTCCGTTACGAGATCCCCACGCACGGCATGCGGCAAGG
CAATTGGACGAGGTGACGGC

Downstream 100 bases:

>100_bases
TACCGACGGATACTGCGCGGCGATCCGCCAGATGGGCGTCGAGCCCCCAAAGGGTGGCGGACAGGCGGCGCTGACCCTGT
CGCCGAGGACCGAACCGAAA

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MADALTSKVARRLLPFLMLCYFFAYLDRVNVGFAALTMNRDLGLSATAYGFGAGLFFLGYVAFEVPSNLILERVGARLWI
ARIMVTWSLVSASTALVVGEWSFYLVRIGLGLAEAGFFPGIILYLTYWFPARQRAGIVGTFMMAVPLSAAIGAPLSGLVM
SLTDGWLGLAGWQWLYLLEAAPSLLLGIATLFVLTDRPERASWLTAEERASLVARMAEDRRLSPNRTAHLGAALLDPRVL
GLGLVYFGLSTGLYAVGLWLPQIVSGFGFTTTATGFVTAVPYIVSAAGMLLWTRHSDRTGERTRHVAIPTVAAGLALFAA
SRAGTPLLTIAALSAVALGVFAALPTFWTLPTRLLTGSAAAGGIALINALGSLGGFAGPALMGWIRDATGRFDDALAAVA
AVLVVAGLAVLRLGRDIARDTGASADAGPARSPEGDARPAPNQQ

Sequences:

>Translated_444_residues
MADALTSKVARRLLPFLMLCYFFAYLDRVNVGFAALTMNRDLGLSATAYGFGAGLFFLGYVAFEVPSNLILERVGARLWI
ARIMVTWSLVSASTALVVGEWSFYLVRIGLGLAEAGFFPGIILYLTYWFPARQRAGIVGTFMMAVPLSAAIGAPLSGLVM
SLTDGWLGLAGWQWLYLLEAAPSLLLGIATLFVLTDRPERASWLTAEERASLVARMAEDRRLSPNRTAHLGAALLDPRVL
GLGLVYFGLSTGLYAVGLWLPQIVSGFGFTTTATGFVTAVPYIVSAAGMLLWTRHSDRTGERTRHVAIPTVAAGLALFAA
SRAGTPLLTIAALSAVALGVFAALPTFWTLPTRLLTGSAAAGGIALINALGSLGGFAGPALMGWIRDATGRFDDALAAVA
AVLVVAGLAVLRLGRDIARDTGASADAGPARSPEGDARPAPNQQ
>Mature_443_residues
ADALTSKVARRLLPFLMLCYFFAYLDRVNVGFAALTMNRDLGLSATAYGFGAGLFFLGYVAFEVPSNLILERVGARLWIA
RIMVTWSLVSASTALVVGEWSFYLVRIGLGLAEAGFFPGIILYLTYWFPARQRAGIVGTFMMAVPLSAAIGAPLSGLVMS
LTDGWLGLAGWQWLYLLEAAPSLLLGIATLFVLTDRPERASWLTAEERASLVARMAEDRRLSPNRTAHLGAALLDPRVLG
LGLVYFGLSTGLYAVGLWLPQIVSGFGFTTTATGFVTAVPYIVSAAGMLLWTRHSDRTGERTRHVAIPTVAAGLALFAAS
RAGTPLLTIAALSAVALGVFAALPTFWTLPTRLLTGSAAAGGIALINALGSLGGFAGPALMGWIRDATGRFDDALAAVAA
VLVVAGLAVLRLGRDIARDTGASADAGPARSPEGDARPAPNQQ

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=426, Percent_Identity=38.4976525821596, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI2367379, Length=438, Percent_Identity=27.3972602739726, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI87082320, Length=431, Percent_Identity=23.2018561484919, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789152, Length=427, Percent_Identity=24.5901639344262, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI2367193, Length=269, Percent_Identity=24.1635687732342, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789515, Length=425, Percent_Identity=24.4705882352941, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=227, Percent_Identity=27.7533039647577, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=331, Percent_Identity=24.773413897281, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324410, Length=158, Percent_Identity=27.8481012658228, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=203, Percent_Identity=25.615763546798, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584153, Length=358, Percent_Identity=23.463687150838, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46766; Mature: 46635

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADALTSKVARRLLPFLMLCYFFAYLDRVNVGFAALTMNRDLGLSATAYGFGAGLFFLGY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
VAFEVPSNLILERVGARLWIARIMVTWSLVSASTALVVGEWSFYLVRIGLGLAEAGFFPG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHCHHHH
IILYLTYWFPARQRAGIVGTFMMAVPLSAAIGAPLSGLVMSLTDGWLGLAGWQWLYLLEA
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
APSLLLGIATLFVLTDRPERASWLTAEERASLVARMAEDRRLSPNRTAHLGAALLDPRVL
HHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHH
GLGLVYFGLSTGLYAVGLWLPQIVSGFGFTTTATGFVTAVPYIVSAAGMLLWTRHSDRTG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
ERTRHVAIPTVAAGLALFAASRAGTPLLTIAALSAVALGVFAALPTFWTLPTRLLTGSAA
CCCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGGIALINALGSLGGFAGPALMGWIRDATGRFDDALAAVAAVLVVAGLAVLRLGRDIARD
CCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGASADAGPARSPEGDARPAPNQQ
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADALTSKVARRLLPFLMLCYFFAYLDRVNVGFAALTMNRDLGLSATAYGFGAGLFFLGY
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
VAFEVPSNLILERVGARLWIARIMVTWSLVSASTALVVGEWSFYLVRIGLGLAEAGFFPG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHCHHHH
IILYLTYWFPARQRAGIVGTFMMAVPLSAAIGAPLSGLVMSLTDGWLGLAGWQWLYLLEA
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
APSLLLGIATLFVLTDRPERASWLTAEERASLVARMAEDRRLSPNRTAHLGAALLDPRVL
HHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHH
GLGLVYFGLSTGLYAVGLWLPQIVSGFGFTTTATGFVTAVPYIVSAAGMLLWTRHSDRTG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
ERTRHVAIPTVAAGLALFAASRAGTPLLTIAALSAVALGVFAALPTFWTLPTRLLTGSAA
CCCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGGIALINALGSLGGFAGPALMGWIRDATGRFDDALAAVAAVLVVAGLAVLRLGRDIARD
CCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGASADAGPARSPEGDARPAPNQQ
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]