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The map label for this gene is glmM

Identifier: 218533180

GI number: 218533180

Start: 5683971

End: 5685311

Strand: Reverse

Name: glmM

Synonym: Mchl_5306

Alternate gene names: 218533180

Gene position: 5685311-5683971 (Counterclockwise)

Preceding gene: 218533181

Following gene: 218533179

Centisome position: 98.4

GC content: 66.22

Gene sequence:

>1341_bases
TTGCGCAAACACTTCGGAACCGACGGCATCCGTGGACGGGCCAACGTCGTCATCACGCCGGAACTTGCTCTCAAGGTCGG
GCAGGCCGCGGGCGTGATCTTCCAACGTGGCGACCACCGCCACCGCGTCGTGATCGGCAAGGATACCCGGCTCTCGGGAT
ATATGATCGAGACCGCGCTCGTCGCCGGCTTCACCTCCGTCGGCATGGACGTGCTGCTGCTCGGGCCGATGCCGACCCCC
GCCGTCGCCATGCTGACCCGCTCGATGCGCGCCGATATCGGCGTGATGATCTCGGCCTCGCACAACCCATACGAGGATAA
CGGCATCAAGCTGTTCGGCCCCGATGGCTTCAAGCTCAACGACGATCTCGAACTCGAGATCGAAAGCCTGATCGACGGCG
ACATGCGCAACCGCCTCTCCGCTTCGCGCGACCTCGGTCGCGCCAAGCGGATCGAGAGCGTGCATGCCCGCTACATCGAG
TTTGCCAAGCGCACCCTGCCGCGCCACGTCACCCTGGACGGTTTGCGGGTCGTCGTCGATTGCGCCAACGGGGCGGCCTA
CCGCGTCGCGCCGGAAACCCTTTGGGAACTGGGCGCCGAAGTGATTTCCATCGGCGTTGAGCCGGACGGGTTCAACATCA
ACCACGATGTCGGCTCGACCGCGCCCGAGACCCTCGTACAGAAGGTGCGGGAGTTGCGGGCCGATGTTGGGATCGCCCTC
GATGGCGACGCCGACCGTGTGCTGATCGTCGACGAGAAGGGCCAGAAGGTCGATGGCGACCAGCTCATGGCGGCCGTGGC
CCGCTCGTGGCAGGAAGACGAGCGCCTGACCCAGCCGGGACTGGTCGCGACGATCATGTCGAATCTCGGACTCGAACGCT
ACATCAACAGCATCGGTCTCACGCTCGCCCGCACGGCCGTCGGCGATCGCTACGTGCTCGAACATATGCGCCAGCACGGC
TACAATCTCGGCGGCGAACAGTCCGGCCACATCATCATGTCGGATTACGCGACCACGGGCGACGGGCTGGTGGCCGCGCT
TCAGCTCCTCAGCGTCGTCAAGCGCCGCAACCTGCCGGTGAGCGAGGTGTGCCACTGCTTCGAGCCCCTGCCGCAGATCC
TCAAGAACGTCCGCTTCCGTTCCGGTGAGCCCCTGCGCGCGGATTCGGTCGTCACCGCGATCGCCCATGCGAAGGACCGG
CTCGGCCAGTCGGGCCGCCTTGTGATCCGCCCCTCCGGCACCGAGCCTGTGATCCGGGTGATGGCCGAGGGGGACGACCG
TGATCTCGTCGCCGAGGTCGTGGACGAAGTCGTGGACGCCGTCACCCGCGCAGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGAGCAACCGATTCACGATACCCGAGATCCGTTCTGCCGGCCGGGTGCCATTCTGATAATCTGGTCGGTGCGAACCACG
CCGAGCGCGGAGAAGCGACG

Downstream 100 bases:

>100_bases
AGCAATGGGGCCGGAAACGGCCCCAGACCGGGTATCGGATCGGCGACGCAAAGGGCGGGACCGATCCGCCGCCGGGGCAT
CACCGGCGGAAAGCACAAGC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MRKHFGTDGIRGRANVVITPELALKVGQAAGVIFQRGDHRHRVVIGKDTRLSGYMIETALVAGFTSVGMDVLLLGPMPTP
AVAMLTRSMRADIGVMISASHNPYEDNGIKLFGPDGFKLNDDLELEIESLIDGDMRNRLSASRDLGRAKRIESVHARYIE
FAKRTLPRHVTLDGLRVVVDCANGAAYRVAPETLWELGAEVISIGVEPDGFNINHDVGSTAPETLVQKVRELRADVGIAL
DGDADRVLIVDEKGQKVDGDQLMAAVARSWQEDERLTQPGLVATIMSNLGLERYINSIGLTLARTAVGDRYVLEHMRQHG
YNLGGEQSGHIIMSDYATTGDGLVAALQLLSVVKRRNLPVSEVCHCFEPLPQILKNVRFRSGEPLRADSVVTAIAHAKDR
LGQSGRLVIRPSGTEPVIRVMAEGDDRDLVAEVVDEVVDAVTRAAA

Sequences:

>Translated_446_residues
MRKHFGTDGIRGRANVVITPELALKVGQAAGVIFQRGDHRHRVVIGKDTRLSGYMIETALVAGFTSVGMDVLLLGPMPTP
AVAMLTRSMRADIGVMISASHNPYEDNGIKLFGPDGFKLNDDLELEIESLIDGDMRNRLSASRDLGRAKRIESVHARYIE
FAKRTLPRHVTLDGLRVVVDCANGAAYRVAPETLWELGAEVISIGVEPDGFNINHDVGSTAPETLVQKVRELRADVGIAL
DGDADRVLIVDEKGQKVDGDQLMAAVARSWQEDERLTQPGLVATIMSNLGLERYINSIGLTLARTAVGDRYVLEHMRQHG
YNLGGEQSGHIIMSDYATTGDGLVAALQLLSVVKRRNLPVSEVCHCFEPLPQILKNVRFRSGEPLRADSVVTAIAHAKDR
LGQSGRLVIRPSGTEPVIRVMAEGDDRDLVAEVVDEVVDAVTRAAA
>Mature_446_residues
MRKHFGTDGIRGRANVVITPELALKVGQAAGVIFQRGDHRHRVVIGKDTRLSGYMIETALVAGFTSVGMDVLLLGPMPTP
AVAMLTRSMRADIGVMISASHNPYEDNGIKLFGPDGFKLNDDLELEIESLIDGDMRNRLSASRDLGRAKRIESVHARYIE
FAKRTLPRHVTLDGLRVVVDCANGAAYRVAPETLWELGAEVISIGVEPDGFNINHDVGSTAPETLVQKVRELRADVGIAL
DGDADRVLIVDEKGQKVDGDQLMAAVARSWQEDERLTQPGLVATIMSNLGLERYINSIGLTLARTAVGDRYVLEHMRQHG
YNLGGEQSGHIIMSDYATTGDGLVAALQLLSVVKRRNLPVSEVCHCFEPLPQILKNVRFRSGEPLRADSVVTAIAHAKDR
LGQSGRLVIRPSGTEPVIRVMAEGDDRDLVAEVVDEVVDAVTRAAA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=445, Percent_Identity=50.561797752809, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1788361, Length=450, Percent_Identity=26.6666666666667, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_METC4 (B7KWJ1)

Other databases:

- EMBL:   CP001298
- RefSeq:   YP_002423996.1
- ProteinModelPortal:   B7KWJ1
- SMR:   B7KWJ1
- GeneID:   7118407
- GenomeReviews:   CP001298_GR
- KEGG:   mch:Mchl_5306
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- ProtClustDB:   PRK14315
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48511; Mature: 48511

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 100-100

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKHFGTDGIRGRANVVITPELALKVGQAAGVIFQRGDHRHRVVIGKDTRLSGYMIETAL
CCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCHHHHHHH
VAGFTSVGMDVLLLGPMPTPAVAMLTRSMRADIGVMISASHNPYEDNGIKLFGPDGFKLN
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCEEC
DDLELEIESLIDGDMRNRLSASRDLGRAKRIESVHARYIEFAKRTLPRHVTLDGLRVVVD
CCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEE
CANGAAYRVAPETLWELGAEVISIGVEPDGFNINHDVGSTAPETLVQKVRELRADVGIAL
CCCCCEEEECHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEE
DGDADRVLIVDEKGQKVDGDQLMAAVARSWQEDERLTQPGLVATIMSNLGLERYINSIGL
ECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHH
TLARTAVGDRYVLEHMRQHGYNLGGEQSGHIIMSDYATTGDGLVAALQLLSVVKRRNLPV
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCH
SEVCHCFEPLPQILKNVRFRSGEPLRADSVVTAIAHAKDRLGQSGRLVIRPSGTEPVIRV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEE
MAEGDDRDLVAEVVDEVVDAVTRAAA
EECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKHFGTDGIRGRANVVITPELALKVGQAAGVIFQRGDHRHRVVIGKDTRLSGYMIETAL
CCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCHHHHHHH
VAGFTSVGMDVLLLGPMPTPAVAMLTRSMRADIGVMISASHNPYEDNGIKLFGPDGFKLN
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCEEC
DDLELEIESLIDGDMRNRLSASRDLGRAKRIESVHARYIEFAKRTLPRHVTLDGLRVVVD
CCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEE
CANGAAYRVAPETLWELGAEVISIGVEPDGFNINHDVGSTAPETLVQKVRELRADVGIAL
CCCCCEEEECHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEE
DGDADRVLIVDEKGQKVDGDQLMAAVARSWQEDERLTQPGLVATIMSNLGLERYINSIGL
ECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHH
TLARTAVGDRYVLEHMRQHGYNLGGEQSGHIIMSDYATTGDGLVAALQLLSVVKRRNLPV
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCH
SEVCHCFEPLPQILKNVRFRSGEPLRADSVVTAIAHAKDRLGQSGRLVIRPSGTEPVIRV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEE
MAEGDDRDLVAEVVDEVVDAVTRAAA
EECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA