Click here to switch to the map view.

The map label for this gene is dnaJ2 [H]

Identifier: 218532548

GI number: 218532548

Start: 4944211

End: 4945161

Strand: Reverse

Name: dnaJ2 [H]

Synonym: Mchl_4662

Alternate gene names: 218532548

Gene position: 4945161-4944211 (Counterclockwise)

Preceding gene: 218532549

Following gene: 218532547

Centisome position: 85.59

GC content: 71.92

Gene sequence:

>951_bases
ATGCCGATGCGAAACCCCTACGACGTTCTGGGTGTCCCCAAGGGCGCGAGCGAGGCCGAAATCAAGAAGGCCTTCCGCAA
GCTCGCCAAGGCGTACCACCCCGACAGCAACAAAGAGCCGAAGGCCGCCGAGCGCTTCTCGGAGGCGAACACCGCCTATG
AGATCCTCGGCGACAAGGAGAAGCGCGCGCAGTTCGACCGCGGCGAGATCGACGCCGAAGGCAAGCCGCGCGCGACCGGC
TTCGAGGGCTTTTCCGGGTTCGGCGGCGGACGCGGCGGCGGTGGCGGCGGCTTCGACTTCGAAGGCTTTACGCAGCGCCG
CGGCGGCGCTGGCGGGGCCGGGCCGGGCGGCGTCGGAGAGGACTTCATCAGCCACATCTTCGGTGAGGCGTTCCGCGCGG
GCGGCGCCGGGCCGGGTGGGCGCGGCGGGCCGATCCGCGGCGAAGATGTCGCGGCCGAACTCAGCGTGACGCTCGAACAG
GTCGCGGGCGAGGACAAGATGCGCATCGGCCTGCCGGGCGGGCGCGATGTCGACGTGATGATCCCCAAGGGCGTCGTCGA
TGGCCAGACCATCCGCCTGCGGGGTCTCGGCGGCGCGGGCGGTCCCCGCGGCGAGCCCGGCGACGCGCTGCTGACCATCC
GCATCCAGCCCCACCCGGTGTTCAAGGTGGACGGCGCGGACCTGCGCGCCACCGTCGATCTGCCGCTGGAGGACGCGGTG
CTCGGCGGCGCCTTGCGTGTGCCGAGCCTGACCGGCGCGGTCGAGATGAAGGTGCCGGCGATGACGAGTTCCGGCCGCAC
TTTCCGCCTGCGCGGAAAGGGCCTGCCGAAGAAGGACGGCAGCCGCGGCGACCTGTTCGCGACCACCGCCATCGTCCTGC
CGGCCAGCGACGACGCTGCCCTGACCGAATATGCCCGCCGCCGCCGCGAGGCCAAGGCCGGGACGGCGTAA

Upstream 100 bases:

>100_bases
ACGGGGCCTCATCGGCTGTTGCAGAGCCGCAACGCCCTTCCCACGTTGAACCCGTGCGGCAGAGGCCGTATCCCTATTCG
GTTGCGACCCCCTCAAAAGA

Downstream 100 bases:

>100_bases
AGGACGCCGTGCCGGAGGGCAGGCCTCGGCTTCTGCCGAGGCGTCGAGCGGAGCGAATCCTAAGGGTTAGCACTATTCGC
GGATGGGCGGAGGGTCATCG

Product: heat shock protein DnaJ domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPMRNPYDVLGVPKGASEAEIKKAFRKLAKAYHPDSNKEPKAAERFSEANTAYEILGDKEKRAQFDRGEIDAEGKPRATG
FEGFSGFGGGRGGGGGGFDFEGFTQRRGGAGGAGPGGVGEDFISHIFGEAFRAGGAGPGGRGGPIRGEDVAAELSVTLEQ
VAGEDKMRIGLPGGRDVDVMIPKGVVDGQTIRLRGLGGAGGPRGEPGDALLTIRIQPHPVFKVDGADLRATVDLPLEDAV
LGGALRVPSLTGAVEMKVPAMTSSGRTFRLRGKGLPKKDGSRGDLFATTAIVLPASDDAALTEYARRRREAKAGTA

Sequences:

>Translated_316_residues
MPMRNPYDVLGVPKGASEAEIKKAFRKLAKAYHPDSNKEPKAAERFSEANTAYEILGDKEKRAQFDRGEIDAEGKPRATG
FEGFSGFGGGRGGGGGGFDFEGFTQRRGGAGGAGPGGVGEDFISHIFGEAFRAGGAGPGGRGGPIRGEDVAAELSVTLEQ
VAGEDKMRIGLPGGRDVDVMIPKGVVDGQTIRLRGLGGAGGPRGEPGDALLTIRIQPHPVFKVDGADLRATVDLPLEDAV
LGGALRVPSLTGAVEMKVPAMTSSGRTFRLRGKGLPKKDGSRGDLFATTAIVLPASDDAALTEYARRRREAKAGTA
>Mature_315_residues
PMRNPYDVLGVPKGASEAEIKKAFRKLAKAYHPDSNKEPKAAERFSEANTAYEILGDKEKRAQFDRGEIDAEGKPRATGF
EGFSGFGGGRGGGGGGFDFEGFTQRRGGAGGAGPGGVGEDFISHIFGEAFRAGGAGPGGRGGPIRGEDVAAELSVTLEQV
AGEDKMRIGLPGGRDVDVMIPKGVVDGQTIRLRGLGGAGGPRGEPGDALLTIRIQPHPVFKVDGADLRATVDLPLEDAVL
GGALRVPSLTGAVEMKVPAMTSSGRTFRLRGKGLPKKDGSRGDLFATTAIVLPASDDAALTEYARRRREAKAGTA

Specific function: Does not influence ATP binding or hydrolysis nor ADP release. Exerts influence on the interaction of dnaK with substrates; in the presence of dafA, dnaJ inhibits substrate binding, and substrate already bound to dnaK is displaced by dnaJ and dafA [H]

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=344, Percent_Identity=29.6511627906977, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI205360840, Length=344, Percent_Identity=29.6511627906977, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI6631085, Length=349, Percent_Identity=30.3724928366762, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI201862587, Length=332, Percent_Identity=29.5180722891566, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI201862518, Length=332, Percent_Identity=29.5180722891566, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI56549115, Length=332, Percent_Identity=29.5180722891566, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI5453690, Length=335, Percent_Identity=29.2537313432836, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI7706495, Length=332, Percent_Identity=30.1204819277108, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI194328760, Length=343, Percent_Identity=26.530612244898, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI194328758, Length=343, Percent_Identity=26.530612244898, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4504511, Length=281, Percent_Identity=29.1814946619217, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI9558755, Length=101, Percent_Identity=43.5643564356436, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5031741, Length=61, Percent_Identity=60.655737704918, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI56687498, Length=63, Percent_Identity=52.3809523809524, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI194306642, Length=65, Percent_Identity=46.1538461538462, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI194306640, Length=65, Percent_Identity=46.1538461538462, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI29126218, Length=62, Percent_Identity=51.6129032258064, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI27151736, Length=105, Percent_Identity=40.9523809523809, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI88501736, Length=105, Percent_Identity=40.9523809523809, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI47777312, Length=75, Percent_Identity=52, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI23503241, Length=72, Percent_Identity=47.2222222222222, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI72534740, Length=64, Percent_Identity=46.875, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787235, Length=319, Percent_Identity=32.9153605015674, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786197, Length=122, Percent_Identity=37.7049180327869, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534355, Length=339, Percent_Identity=31.858407079646, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI212645553, Length=65, Percent_Identity=53.8461538461538, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17507263, Length=61, Percent_Identity=50.8196721311475, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554644, Length=74, Percent_Identity=48.6486486486487, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17553096, Length=60, Percent_Identity=48.3333333333333, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17553098, Length=60, Percent_Identity=48.3333333333333, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324321, Length=342, Percent_Identity=26.6081871345029, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324265, Length=155, Percent_Identity=38.0645161290323, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323813, Length=134, Percent_Identity=41.044776119403, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321094, Length=114, Percent_Identity=44.7368421052632, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322194, Length=62, Percent_Identity=50, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658562, Length=330, Percent_Identity=32.7272727272727, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24658555, Length=330, Percent_Identity=32.7272727272727, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI85726398, Length=353, Percent_Identity=30.5949008498584, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI18858081, Length=339, Percent_Identity=30.0884955752212, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19920464, Length=324, Percent_Identity=30.5555555555556, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI20129487, Length=355, Percent_Identity=27.887323943662, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24584014, Length=355, Percent_Identity=27.887323943662, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355911, Length=103, Percent_Identity=43.6893203883495, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45549272, Length=64, Percent_Identity=50, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45552813, Length=64, Percent_Identity=50, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45552811, Length=64, Percent_Identity=50, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24668492, Length=79, Percent_Identity=41.7721518987342, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17648033, Length=109, Percent_Identity=37.6146788990826, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24584630, Length=109, Percent_Identity=37.6146788990826, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646562, Length=62, Percent_Identity=50, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646560, Length=62, Percent_Identity=50, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646558, Length=62, Percent_Identity=50, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646556, Length=62, Percent_Identity=50, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357547, Length=62, Percent_Identity=50, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C [H]

EC number: NA

Molecular weight: Translated: 32771; Mature: 32640

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMRNPYDVLGVPKGASEAEIKKAFRKLAKAYHPDSNKEPKAAERFSEANTAYEILGDKE
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEHHCCHH
KRAQFDRGEIDAEGKPRATGFEGFSGFGGGRGGGGGGFDFEGFTQRRGGAGGAGPGGVGE
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHH
DFISHIFGEAFRAGGAGPGGRGGPIRGEDVAAELSVTLEQVAGEDKMRIGLPGGRDVDVM
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEE
IPKGVVDGQTIRLRGLGGAGGPRGEPGDALLTIRIQPHPVFKVDGADLRATVDLPLEDAV
ECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEECCCCEEEEECCCHHHHH
LGGALRVPSLTGAVEMKVPAMTSSGRTFRLRGKGLPKKDGSRGDLFATTAIVLPASDDAA
HCCEEECCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCHH
LTEYARRRREAKAGTA
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PMRNPYDVLGVPKGASEAEIKKAFRKLAKAYHPDSNKEPKAAERFSEANTAYEILGDKE
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEHHCCHH
KRAQFDRGEIDAEGKPRATGFEGFSGFGGGRGGGGGGFDFEGFTQRRGGAGGAGPGGVGE
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHH
DFISHIFGEAFRAGGAGPGGRGGPIRGEDVAAELSVTLEQVAGEDKMRIGLPGGRDVDVM
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEE
IPKGVVDGQTIRLRGLGGAGGPRGEPGDALLTIRIQPHPVFKVDGADLRATVDLPLEDAV
ECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEECCCCEEEEECCCHHHHH
LGGALRVPSLTGAVEMKVPAMTSSGRTFRLRGKGLPKKDGSRGDLFATTAIVLPASDDAA
HCCEEECCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCHH
LTEYARRRREAKAGTA
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9349721; 9276481; 10092456 [H]