Click here to switch to the map view.

The map label for this gene is recG [H]

Identifier: 218532418

GI number: 218532418

Start: 4797411

End: 4799600

Strand: Reverse

Name: recG [H]

Synonym: Mchl_4530

Alternate gene names: 218532418

Gene position: 4799600-4797411 (Counterclockwise)

Preceding gene: 218532424

Following gene: 218532417

Centisome position: 83.07

GC content: 72.6

Gene sequence:

>2190_bases
ATGACCTCGGATACCAGCCAGACCCTCGGGCACCCTGCTGATGCGGCCCCTCCCCGCTCCGGCGGGGACGTCGCCCCCGG
CCTTCGCCCCAGCCTCCTCGACCCGCTCTTCGCCCCCGCCCGCGGTCTGCCCGGCGTCGGGCCGAAGATCGCGCCGCTCA
TCGAAAAGCTGCTCGGCTCCGAGGAGCGGCCGGCCCGCGTCGCCGACCTGCTGTTCCACCTGCCTCAAAGCGGGGTCGCC
CGGCCGCTCTGCGGCTCGATCCGCGATGCGCCGACGGGTGAGCCCATCACGCTGGGCGTCACTGTGGTGGCCCACCGGCC
GCCGATGCTCGGCAAGCGGGCCTTCCGGGTGCTGGTCGAGGACGGGACTGGCGACATCAGCCTTGTCTTCTTCGGCATGC
CGCGGGGCCGCATCGAGAAGATGCTGCCGCTCGGCAGCCACCGCTACGTCTCAGGGAGGATCGACCTGTGGGACGGCACG
CGGCAGATGGTGCATCCCTCGCGCATCCTCGACCAGGAGGGGTTGGCCAGCCTGCCCGCCGTCGAGCCGATCTACGGCGC
GACCGAGGGGCTGACCTCGCGGGTCATCAGCCGGATCGTCCACGGCGCGCTCGACCGGCTTCCGGTGCTGCCCGAGTGGC
AGGATGCGTCCTATCTCGCCCGCAACCGCTTTCCCCCCTTCGCCGAGGCTCTGCGCATCGAGCACCGGCCCGAGGAGGCG
CCCCCGCCCCCGGTCGAGGGGCAGGCGCCGCCCACGAGCCCCGCACGCAAGCGCCTCGCCTACGACGAGCTGCTCGCCTC
GCAGCTTGCGCTCGCCCTGGTACGCGCCCGGCAGCGGCGGAAGCCCGGCCGGGTCAATGCCGGCGACGGGCATCTGAAAG
AGCGCGTCGAGGCAGCACTTCCCTTCGCGCTGACCGGCGCGCAGGCGCGGGCGGTCGACGAAATCCGCGCCGACATGGCC
GCCGAGCGGCGGATGCTGCGCCTGCTCCAGGGCGATGTCGGCTCCGGCAAGACGGCGGTGGCGTTGCTCGCGATGGCCTC
GGCGGTGGAGGCCGGGCGGCAGGCGGCGCTGATGGCGCCAACCGAGATTCTGGCGCGCCAACATTACGAGCGACTGGTGC
CGCTGGCCGGCGCCATGCGCCTGCGGCTGCTGACCGGCCGCGACCGGGCCGCCGAGCGTCGCGCGACGCTGGCGGATCTC
GCGGCGGGCGAGATCGACATCGTGGTCGGCACCCACGCTCTGTTCCAGGAGTCGGTGGCGTTCCGCGATCTCGGCCTCGC
AGTGGTGGACGAGCAGCACCGCTTCGGCGTGCATCAGCGCCTCGCGCTCGGCGCCAAGGGCGAGGCGGTGGACATCCTCG
TGATGACCGCCACCCCGATCCCGCGCACGCTGGCACTCACCTTCTTCGGCGACATGGACGTCTCGGTGCTCGACGAGAAG
CCGGCCGGGCGCCAGCCGATCAAGACCATCACCGTGCCGGTGGAGCGCATCGACGAGGTGGTGGGCGGCCTGCACCGGGC
CCTGGCCGCGGGCGACCGGGTCTATTGGATCTGCCCGCTGGTCGCCGAATCGGAATATGTCGACCTCGCCGCCGCCGCCG
AGCGGTTCGAGGATCTGCAGAAGCATTTCGGCGACGCGGTCGGCCTGATCCATGGCAAGATGCCGGGGCCGGAGAAGGAC
GCGGCGATGGAGGCCTTCGCCGCCGGCCGCACCCGCGTGCTGGTCTCGACCACCGTCGTGGAGGTCGGCGTCGATGTGCC
GGAGGCCACCATCATGGTGATCGAGCATGCCGAGCGCTTCGGGCTGGCCCAGCTTCACCAGCTCCGCGGCCGGGTCGGGC
GCGGCTCGAAGGCCTCCTCCTGCCTGCTGCTCTATCGCGGGCCCCTCGGCCAGGTCGCCAAGGCGCGCCTGGAGATGATG
CGAGGCAGCGAGGACGGTTTTCGCATCGCCGAGGAAGACCTGCGCCTGCGCGGCGAGGGCGAGGTGCTCGGCACCCGCCA
ATCCGGCGCCGCCGCCTTCCGCCTTGCCCGGCTCGAGACCGACGGCGACCTGTTGGAGGCCGCCCGCGACGACGCCCGGC
TGATCGTGGAGCGCGACCCGCGCCTCGCGAGCGAGCGCGGCCGGGCGCTCAGGGTGCTGCTCTACCTGTTCGAGCGCGAA
GCGGCGATCCGGCTGATCGGGGCAGGCTAA

Upstream 100 bases:

>100_bases
ACGCGCATGATGTCATATGCCCAGATGCGACGGAGGCAGGAAGCAGGGTATACGGAGCCCGAGCATCGCCCACGTTTCAA
AGGCCCAAGCCTCCGGTCAC

Downstream 100 bases:

>100_bases
CGGAGCGTTCGCGCGGCGATCGGGCAAAGCCCTTTTCCGCCATAGGAGGGAGCGCCTCGGACGCCGAATATGATCGCCCG
TTCAGAAACCCGTTCAGAAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MTSDTSQTLGHPADAAPPRSGGDVAPGLRPSLLDPLFAPARGLPGVGPKIAPLIEKLLGSEERPARVADLLFHLPQSGVA
RPLCGSIRDAPTGEPITLGVTVVAHRPPMLGKRAFRVLVEDGTGDISLVFFGMPRGRIEKMLPLGSHRYVSGRIDLWDGT
RQMVHPSRILDQEGLASLPAVEPIYGATEGLTSRVISRIVHGALDRLPVLPEWQDASYLARNRFPPFAEALRIEHRPEEA
PPPPVEGQAPPTSPARKRLAYDELLASQLALALVRARQRRKPGRVNAGDGHLKERVEAALPFALTGAQARAVDEIRADMA
AERRMLRLLQGDVGSGKTAVALLAMASAVEAGRQAALMAPTEILARQHYERLVPLAGAMRLRLLTGRDRAAERRATLADL
AAGEIDIVVGTHALFQESVAFRDLGLAVVDEQHRFGVHQRLALGAKGEAVDILVMTATPIPRTLALTFFGDMDVSVLDEK
PAGRQPIKTITVPVERIDEVVGGLHRALAAGDRVYWICPLVAESEYVDLAAAAERFEDLQKHFGDAVGLIHGKMPGPEKD
AAMEAFAAGRTRVLVSTTVVEVGVDVPEATIMVIEHAERFGLAQLHQLRGRVGRGSKASSCLLLYRGPLGQVAKARLEMM
RGSEDGFRIAEEDLRLRGEGEVLGTRQSGAAAFRLARLETDGDLLEAARDDARLIVERDPRLASERGRALRVLLYLFERE
AAIRLIGAG

Sequences:

>Translated_729_residues
MTSDTSQTLGHPADAAPPRSGGDVAPGLRPSLLDPLFAPARGLPGVGPKIAPLIEKLLGSEERPARVADLLFHLPQSGVA
RPLCGSIRDAPTGEPITLGVTVVAHRPPMLGKRAFRVLVEDGTGDISLVFFGMPRGRIEKMLPLGSHRYVSGRIDLWDGT
RQMVHPSRILDQEGLASLPAVEPIYGATEGLTSRVISRIVHGALDRLPVLPEWQDASYLARNRFPPFAEALRIEHRPEEA
PPPPVEGQAPPTSPARKRLAYDELLASQLALALVRARQRRKPGRVNAGDGHLKERVEAALPFALTGAQARAVDEIRADMA
AERRMLRLLQGDVGSGKTAVALLAMASAVEAGRQAALMAPTEILARQHYERLVPLAGAMRLRLLTGRDRAAERRATLADL
AAGEIDIVVGTHALFQESVAFRDLGLAVVDEQHRFGVHQRLALGAKGEAVDILVMTATPIPRTLALTFFGDMDVSVLDEK
PAGRQPIKTITVPVERIDEVVGGLHRALAAGDRVYWICPLVAESEYVDLAAAAERFEDLQKHFGDAVGLIHGKMPGPEKD
AAMEAFAAGRTRVLVSTTVVEVGVDVPEATIMVIEHAERFGLAQLHQLRGRVGRGSKASSCLLLYRGPLGQVAKARLEMM
RGSEDGFRIAEEDLRLRGEGEVLGTRQSGAAAFRLARLETDGDLLEAARDDARLIVERDPRLASERGRALRVLLYLFERE
AAIRLIGAG
>Mature_728_residues
TSDTSQTLGHPADAAPPRSGGDVAPGLRPSLLDPLFAPARGLPGVGPKIAPLIEKLLGSEERPARVADLLFHLPQSGVAR
PLCGSIRDAPTGEPITLGVTVVAHRPPMLGKRAFRVLVEDGTGDISLVFFGMPRGRIEKMLPLGSHRYVSGRIDLWDGTR
QMVHPSRILDQEGLASLPAVEPIYGATEGLTSRVISRIVHGALDRLPVLPEWQDASYLARNRFPPFAEALRIEHRPEEAP
PPPVEGQAPPTSPARKRLAYDELLASQLALALVRARQRRKPGRVNAGDGHLKERVEAALPFALTGAQARAVDEIRADMAA
ERRMLRLLQGDVGSGKTAVALLAMASAVEAGRQAALMAPTEILARQHYERLVPLAGAMRLRLLTGRDRAAERRATLADLA
AGEIDIVVGTHALFQESVAFRDLGLAVVDEQHRFGVHQRLALGAKGEAVDILVMTATPIPRTLALTFFGDMDVSVLDEKP
AGRQPIKTITVPVERIDEVVGGLHRALAAGDRVYWICPLVAESEYVDLAAAAERFEDLQKHFGDAVGLIHGKMPGPEKDA
AMEAFAAGRTRVLVSTTVVEVGVDVPEATIMVIEHAERFGLAQLHQLRGRVGRGSKASSCLLLYRGPLGQVAKARLEMMR
GSEDGFRIAEEDLRLRGEGEVLGTRQSGAAAFRLARLETDGDLLEAARDDARLIVERDPRLASERGRALRVLLYLFEREA
AIRLIGAG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=701, Percent_Identity=40.3708987161198, Blast_Score=437, Evalue=1e-123,
Organism=Escherichia coli, GI1787357, Length=406, Percent_Identity=39.6551724137931, Blast_Score=255, Evalue=6e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78725; Mature: 78594

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDTSQTLGHPADAAPPRSGGDVAPGLRPSLLDPLFAPARGLPGVGPKIAPLIEKLLGS
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
EERPARVADLLFHLPQSGVARPLCGSIRDAPTGEPITLGVTVVAHRPPMLGKRAFRVLVE
CCCCHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHEEEEEEE
DGTGDISLVFFGMPRGRIEKMLPLGSHRYVSGRIDLWDGTRQMVHPSRILDQEGLASLPA
CCCCCEEEEEEECCHHHHHHHCCCCCCEEEECEEEECCCCHHHCCHHHHHCCCCCCCCCC
VEPIYGATEGLTSRVISRIVHGALDRLPVLPEWQDASYLARNRFPPFAEALRIEHRPEEA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCC
PPPPVEGQAPPTSPARKRLAYDELLASQLALALVRARQRRKPGRVNAGDGHLKERVEAAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
PFALTGAQARAVDEIRADMAAERRMLRLLQGDVGSGKTAVALLAMASAVEAGRQAALMAP
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEECCCH
TEILARQHYERLVPLAGAMRLRLLTGRDRAAERRATLADLAAGEIDIVVGTHALFQESVA
HHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
FRDLGLAVVDEQHRFGVHQRLALGAKGEAVDILVMTATPIPRTLALTFFGDMDVSVLDEK
HHHCCCCEECCHHHCCHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEECCCCEEEECCC
PAGRQPIKTITVPVERIDEVVGGLHRALAAGDRVYWICPLVAESEYVDLAAAAERFEDLQ
CCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
KHFGDAVGLIHGKMPGPEKDAAMEAFAAGRTRVLVSTTVVEVGVDVPEATIMVIEHAERF
HHHCHHEEEHCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEEEHHHHHH
GLAQLHQLRGRVGRGSKASSCLLLYRGPLGQVAKARLEMMRGSEDGFRIAEEDLRLRGEG
HHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEHHHHEECCCC
EVLGTRQSGAAAFRLARLETDGDLLEAARDDARLIVERDPRLASERGRALRVLLYLFERE
CEEECCCCCCHHEEEEEECCCHHHHHHCCCCCEEEEECCCCCHHHHCHHHHHHHHHHHCC
AAIRLIGAG
CEEEEEECC
>Mature Secondary Structure 
TSDTSQTLGHPADAAPPRSGGDVAPGLRPSLLDPLFAPARGLPGVGPKIAPLIEKLLGS
CCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
EERPARVADLLFHLPQSGVARPLCGSIRDAPTGEPITLGVTVVAHRPPMLGKRAFRVLVE
CCCCHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHEEEEEEE
DGTGDISLVFFGMPRGRIEKMLPLGSHRYVSGRIDLWDGTRQMVHPSRILDQEGLASLPA
CCCCCEEEEEEECCHHHHHHHCCCCCCEEEECEEEECCCCHHHCCHHHHHCCCCCCCCCC
VEPIYGATEGLTSRVISRIVHGALDRLPVLPEWQDASYLARNRFPPFAEALRIEHRPEEA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCC
PPPPVEGQAPPTSPARKRLAYDELLASQLALALVRARQRRKPGRVNAGDGHLKERVEAAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
PFALTGAQARAVDEIRADMAAERRMLRLLQGDVGSGKTAVALLAMASAVEAGRQAALMAP
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEECCCH
TEILARQHYERLVPLAGAMRLRLLTGRDRAAERRATLADLAAGEIDIVVGTHALFQESVA
HHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
FRDLGLAVVDEQHRFGVHQRLALGAKGEAVDILVMTATPIPRTLALTFFGDMDVSVLDEK
HHHCCCCEECCHHHCCHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEECCCCEEEECCC
PAGRQPIKTITVPVERIDEVVGGLHRALAAGDRVYWICPLVAESEYVDLAAAAERFEDLQ
CCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
KHFGDAVGLIHGKMPGPEKDAAMEAFAAGRTRVLVSTTVVEVGVDVPEATIMVIEHAERF
HHHCHHEEEHCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEEEHHHHHH
GLAQLHQLRGRVGRGSKASSCLLLYRGPLGQVAKARLEMMRGSEDGFRIAEEDLRLRGEG
HHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEHHHHEECCCC
EVLGTRQSGAAAFRLARLETDGDLLEAARDDARLIVERDPRLASERGRALRVLLYLFERE
CEEECCCCCCHHEEEEEECCCHHHHHHCCCCCEEEEECCCCCHHHHCHHHHHHHHHHHCC
AAIRLIGAG
CEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]