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The map label for this gene is gst [C]

Identifier: 218532282

GI number: 218532282

Start: 4643424

End: 4644065

Strand: Reverse

Name: gst [C]

Synonym: Mchl_4394

Alternate gene names: 218532282

Gene position: 4644065-4643424 (Counterclockwise)

Preceding gene: 218532283

Following gene: 218532281

Centisome position: 80.38

GC content: 70.87

Gene sequence:

>642_bases
ATGTCCGACGATCTCGTCTTCTACACCAACCCGATGTCCCGCGGCCGGATCGTCCGCTGGATGCTGGAAGAGGTCGGCGC
GCCCTACCGCACCGAGATCCTCGGCTACGGCAGCTCTATGAAGGCGCCGGCATACCGGGCGATCAACCCGATGGGGAAGG
TGCCGGCGCTGCGCCACGGCGAGACGGTGGTGACCGAGTGCCCCGCGATCCTGGCCTATCTCGCCGACGCCTTCCCGCAG
GCCGGGCTCGCCCCCGCGCCGGGCCACCACGACCGCGGCCCCTATTATCGCTGGCTGTTCTTCTGCGCCGGGCCGCTCGA
GGCGGCGGTCACGAACGGCGTGCTCAAGGTGAGCGTCCCCGACGACCCGCGCATGCAGGGCATGGTCGGCTACGGCAGCC
TGGAGATGGCCCTCGACACGCTTGAAGGCGCCGTCTCCGGGGTGGAGTTCGTGGCAGGCGACCGGTTCAGCGCCGCCGAC
CTCTACGTCGCCGCACATCTCGGCTGGGGCATGCAGTTCGGTACGATCCCGAAGCGCCCGGCCTTCGAGGCCTATGCCGG
GCGCCACCTCGCCCGCGAGGCGGCCGCGCGGGCGCGGGCGATCGATGACGCTTTTCTCGCCGAGGCGCAGGCGGCGTCAT
AG

Upstream 100 bases:

>100_bases
GGTTCTGACCCGCGAGGGCGCCCGAGGCTTCCGCGCCCGCGCGCCCTCCCCTAACACCGGGGCGACGCCCGCCCTGCGGG
CGCCTCGCCCCGGAGCCCCC

Downstream 100 bases:

>100_bases
TCGCCGACCGACGGAACGGCCCCGCCCGCCCCGCGTTCGCCCCGCGAAGTCGCACGAGCGTCGAGAAGGAGTGCGTTGAC
CGTGAACGAGATGATCGAGG

Product: glutathione S-transferase domain

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase Domain-Containing Protein; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase-Like; Glutathione S-Transferase Family Protein; Glutathione S-Transferase Protein; Glutathione Transferase; Glutathione S-Transferase Domain; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione S-Transferase N-Terminal Domain-Containing; Transcriptional Regulator; Glutathione S Transferase; GSH-Dependent Dehydroascorbate Reductase; Gluthione S-Transferase

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSDDLVFYTNPMSRGRIVRWMLEEVGAPYRTEILGYGSSMKAPAYRAINPMGKVPALRHGETVVTECPAILAYLADAFPQ
AGLAPAPGHHDRGPYYRWLFFCAGPLEAAVTNGVLKVSVPDDPRMQGMVGYGSLEMALDTLEGAVSGVEFVAGDRFSAAD
LYVAAHLGWGMQFGTIPKRPAFEAYAGRHLAREAAARARAIDDAFLAEAQAAS

Sequences:

>Translated_213_residues
MSDDLVFYTNPMSRGRIVRWMLEEVGAPYRTEILGYGSSMKAPAYRAINPMGKVPALRHGETVVTECPAILAYLADAFPQ
AGLAPAPGHHDRGPYYRWLFFCAGPLEAAVTNGVLKVSVPDDPRMQGMVGYGSLEMALDTLEGAVSGVEFVAGDRFSAAD
LYVAAHLGWGMQFGTIPKRPAFEAYAGRHLAREAAARARAIDDAFLAEAQAAS
>Mature_212_residues
SDDLVFYTNPMSRGRIVRWMLEEVGAPYRTEILGYGSSMKAPAYRAINPMGKVPALRHGETVVTECPAILAYLADAFPQA
GLAPAPGHHDRGPYYRWLFFCAGPLEAAVTNGVLKVSVPDDPRMQGMVGYGSLEMALDTLEGAVSGVEFVAGDRFSAADL
YVAAHLGWGMQFGTIPKRPAFEAYAGRHLAREAAARARAIDDAFLAEAQAAS

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 22926; Mature: 22795

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDLVFYTNPMSRGRIVRWMLEEVGAPYRTEILGYGSSMKAPAYRAINPMGKVPALRHG
CCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHEEECCCCCCCCCHHHCCCCCCCCCCCCC
ETVVTECPAILAYLADAFPQAGLAPAPGHHDRGPYYRWLFFCAGPLEAAVTNGVLKVSVP
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHCCEEEEECC
DDPRMQGMVGYGSLEMALDTLEGAVSGVEFVAGDRFSAADLYVAAHLGWGMQFGTIPKRP
CCCCCCCEECCCHHHHHHHHHHHHHHCHHHCCCCCCCHHHEEEEEHHCCCCEECCCCCCC
AFEAYAGRHLAREAAARARAIDDAFLAEAQAAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDDLVFYTNPMSRGRIVRWMLEEVGAPYRTEILGYGSSMKAPAYRAINPMGKVPALRHG
CCCEEEEECCCCCCHHHHHHHHHHCCCHHHHEEECCCCCCCCCHHHCCCCCCCCCCCCC
ETVVTECPAILAYLADAFPQAGLAPAPGHHDRGPYYRWLFFCAGPLEAAVTNGVLKVSVP
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHCCEEEEECC
DDPRMQGMVGYGSLEMALDTLEGAVSGVEFVAGDRFSAADLYVAAHLGWGMQFGTIPKRP
CCCCCCCEECCCHHHHHHHHHHHHHHCHHHCCCCCCCHHHEEEEEHHCCCCEECCCCCCC
AFEAYAGRHLAREAAARARAIDDAFLAEAQAAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA